Results 151 to 160 of about 4,440,633 (238)
Alzheimer's disease (AD), a degenerative disease of the central nervous system, is the most common form of dementia in old age. The complexity and behavior of circular RNA (circRNA)-associated competing endogenous RNA (ceRNA) network remained poorly ...
Fulong Yu (3398372) +3 more
core +1 more source
Molecular insights and translational opportunities to enhance heat tolerance in rice
Abstract Heat stress is an increasingly serious threat to rice (Oryza sativa L.) productivity, yet the genetic and regulatory architecture underlying thermotolerance remain poorly resolved and fragmented across studies. Earlier research focused on individual pathways or specific developmental stages; however, recent advances now support an integrated ...
Prabhat Rana +7 more
wiley +1 more source
Alzheimer's disease (AD), a degenerative disease of the central nervous system, is the most common form of dementia in old age. The complexity and behavior of circular RNA (circRNA)-associated competing endogenous RNA (ceRNA) network remained poorly ...
Fulong Yu (3398372) +3 more
core +1 more source
The lncRNA CROCCP2 upregulates HOXD11 by competitively adsorbing miR‐5584‐5p, thereby promoting glioma cell proliferation, migration, and invasion by inhibiting autophagy. It significantly enhances tumor growth in vivo, suggesting it may be a potential therapeutic target for gliomas.
Feng Wang +8 more
wiley +1 more source
ceRNA networks in ischemic stroke: a bibliometric analysis
Abstract Background and method Ischemic stroke, a leading cause of death and disability worldwide, has been increasingly linked to ceRNA networks, which regulate neuronal damage and recovery. Despite growing interest, a comprehensive bibliometric analysis of ceRNA’s role in stroke remains limited.
Loo Keat Wei +2 more
openaire +2 more sources
circMAN1A2 as an Isoform‐Resolved Circular RNA Hub in Cancer
circMAN1A2 as an isoform‐resolved circular RNA hub in cancer. circMAN1A2 is generated by back‐splicing of MAN1A2 pre‐mRNA, with alternative circularization producing multiple isoforms, including the predominant circMAN1A2(2–5). Its mechanistic interfaces include miRNA‐associated regulation, RBP binding/proteostasis control, BSJ‐mediated RNA–RNA pairing,
Hanyu Shang +4 more
wiley +1 more source
Targeting m6A Modifications Regulating Ferroptosis Offers Novel Therapy in Diseases
m6A RNA modification regulates ferroptosis by balancing iron metabolism, lipid peroxidation, and antioxidant defenses. Dysregulated m6A signaling disrupts pro‐ and anti‐ferroptotic factors, leading to excess ROS, Fe3+ accumulation, and lipid peroxidation–driven cell death. Targeting m6A‐mediated ferroptotic regulation represents a promising therapeutic
Lida Du +7 more
wiley +1 more source
Prostate cancer (PCa) ranks among the most prevalent malignant tumors worldwide. The pivotal role of competitive endogenous RNA (ceRNA) regulatory networks in numerous cancer types has been underscored.
Zhi Shang +7 more
doaj +1 more source
Navigating Bicultural Ecologies: Schooling and Life Chances in Roma Communities
ABSTRACT This longitudinal study examines 30 years in the lives of two segregated Roma communities in Hungary by tracing educational trajectories and adult life chances. It analyses acculturation processes, exploring how educational experiences intersect with bicultural home and community socialisation to shape the accumulation and transformation of ...
Aranka Varga, Ábel Bereményi
wiley +1 more source
ABSTRACT Apoptosis and functional loss of articular chondrocytes serve as initiating events in temporomandibular joint osteoarthritis (TMJOA), and FoxO3 represents a critical molecule for sustaining chondrocyte homeostasis. This study investigates the regulatory mechanism of the lncRNA‐OIP5‐AS1/hsa‐miRNA‐223‐3p/FoxO3 axis in TMJOA, aiming to identify ...
Xuesong Xu, Shichong Qiao
wiley +1 more source

