Results 111 to 120 of about 4,583,316 (255)

AI Public Value Creation: Data Encoding, Aggregation, and Algorithmic Computation

Public Administration, EarlyView.
ABSTRACT AI systems in public administration challenge the premise that value creation arises from managers' strategic mediation among the vertices of Moore's strategic triangle: Public value, legitimacy, and operational capacity. AI imposes new logics that reshape vertices and their interaction dynamics.
Antonio Cordella, Francesco Gualdi
wiley   +1 more source

Understanding exosomes in regenerative dentistry

Periodontology 2000, EarlyView.
Abstract Background Regenerative dentistry is shifting from cell‐based strategies to cell‐free biologics capable of orchestrating intricate tissue repair. Exosomes, nanosized extracellular vesicles carrying bioactive molecular payloads, have emerged as central modulators of intercellular communication.
Paras Ahmad, Anton Sculean, Richard J. Miron   +2 more
wiley   +1 more source

Mapping the omics landscape for peri‐implant diseases: A scoping review

Periodontology 2000, EarlyView.
Abstract Objectives To map omics evidence across peri‐implant health, peri‐implant mucositis, and peri‐implantitis, and to identify recurring molecular patterns and candidate biomarker signals relevant to diagnosis, monitoring, and treatment. Materials and Methods This scoping review included human studies using genomics, DNA methylation–based ...
Ethan Ng, Ioannis Fragkioudakis, Jeniffer Perussolo, John Rong Hao Tay, Elena Calciolari, Nikos Donos   +5 more
wiley   +1 more source

Unveiling the immune-related ceRNA network in osteoarthritis: key biomarkers and therapeutic targets

Introduction The aim of this study was to explore the immune-related competitive endogenous RNA (ceRNA) network in osteoarthritis (OA), focusing on identifying differentially expressed long non-coding RNAs (lncRNAs), constructing a classification model ...
Xu Wang, Xin Ma, Wang, Xu, Ma, Xin, Jia-qi Shi, Li Chen, Shi, Jia-qi, Chen, Li   +7 more
core   +1 more source

Twenty eight cancer specific lncRNAs in ceRNA network construction.

, 2015
This table showed 28 cancer specific lncRNAs for ceRNA network construction with absolute fold change ≥ 3.0, P < 0.01 and included in GENCODE.
Paul B. S. Lai (317945), George G. Chen (750164), Dahua Fan (817119), Zhixiang Jian (455888), Jian Zhang (1682)   +4 more
core   +1 more source

Periodontitis and metabolic dysfunction‐associated steatotic liver disease

Periodontology 2000, EarlyView.
Abstract Objective Periodontitis is a chronic inflammatory disease with systemic effects that extend beyond the oral cavity and contribute to systemic immune and metabolic dysregulation. Chronic liver diseases, particularly metabolic dysfunction‐associated steatotic liver disease (MASLD) and its progressive phenotypes, have emerged as major global ...
Rafael Scaf de Molon, Erica Dorigatti de Avila, Davi da Silva Barbirato, Mariana Fampa Fogacci, Jamil Awad Shibli, Anton Sculean, Alpdogan Kantarci   +6 more
wiley   +1 more source

Role of the long non-coding RNA PVT1 in the dysregulation of the ceRNA-ceRNA network in human breast cancer

PLOS ONE, 2017
Recent findings have identified competing endogenous RNAs (ceRNAs) as the drivers in many disease conditions, including cancers. The ceRNAs indirectly regulate each other by reducing the amount of microRNAs (miRNAs) available to target messenger RNAs (mRNAs). The ceRNA interactions mediated by miRNAs are modulated by a titration mechanism, i.e.
Conte F, Fiscon G, Chiara M, Colombo T, Farina L, Paci P   +5 more
openaire   +8 more sources

Supplementary Figure S4 from Comprehensive Analysis of Tumor Microenvironment Reveals Prognostic ceRNA Network Related to Immune Infiltration in Sarcoma

, 2023
Supplementary Figure S4. Construction of global ceRNA network between low and high TIILs SARC subtypes.
Dongliang Leng (17079663), Ka U. Ip (17079678), Qi Zhao (10053729), Heng Sun (17079669), Guokai Chen (14963870), Ziyi Yang (17079666), Xiaohua Douglas Zhang (9398052), Chengcheng Song (17079672), Chen Huang (17079675), Chu-Xia Deng (16721652)   +9 more
core   +1 more source

Identification of a Circular RNA as a Potential Diagnostic and Prognostic Biomarker in Breast Cancer Through Integrated Bioinformatic and Experimental Analyses

Analytical Science Advances, Volume 7, Issue 2, December 2026.
Forty circular RNAs were found to be significantly dysregulated in microarray datasets. Expression levels of hsa_circ_0000231 were significantly upregulated in breast cancer (BC) tissues, while hsa_circ_0011385 exhibited no significant difference in expression levels. This study also revealed that hsa_circ_0000231/hsa‐miR‐5683/CCNB1 regulatory axis may
MohamadReza Hashemi, Pejman Morovat, Azin Khoshghiafeh, Novin Nikbakhsh, Mohamadreza Ahmadifard   +4 more
wiley   +1 more source

Research Ethics in Machine Learning

, 2018
Members of the Machine Learning working group : Laurence Devillers, Professeur Paris-Sorbonne 4, LIMSI-CNRS, CERNA, animatrice du groupe Serge Abiteboul, Directeur de recherche Inria, ENS-Paris, Membre de l’Académie des sciences Danièle Bourcier ...
Collectif, Cerna
core   +2 more sources