Results 91 to 100 of about 19,790 (218)

HumanViCe: host ceRNA network in virus infected cells in human [PDF]

Frontiers in Genetics, 2014
Host-virus interaction via host cellular components has been an important field of research in recent times. RNA interference mediated by short interfering RNAs and microRNAs (miRNA), is a widespread anti-viral defense strategy. Importantly, viruses also encode their own miRNAs.
Suman eGhosal, Shaoli eDas, Rituparno eSen, Jayprokas eChakrabarti, Jayprokas eChakrabarti   +4 more
openaire   +3 more sources

The role of lncRNA-mediated ceRNA regulatory networks in pancreatic cancer

Cell Death Discovery, 2022
AbstractNon-coding RNAs (ncRNAs), which occupy the vast majority of human transcripts are known for their inability to encode proteins. NcRNAs consist of a diverse range of RNA species, including long non-coding RNAs (lncRNAs), which have significant meaning for epigenetic modification, post-transcriptional regulation of target genes, molecular ...
Jichuan Xu, Jian Xu, Xinyuan Liu, Jianxin Jiang   +3 more
openaire   +3 more sources

Table_3_Systematic Characterization of Circular RNA-Associated CeRNA Network Identified Novel circRNA Biomarkers in Alzheimer's Disease.XLSX [PDF]

, 2019
Alzheimer's disease (AD), a degenerative disease of the central nervous system, is the most common form of dementia in old age. The complexity and behavior of circular RNA (circRNA)-associated competing endogenous RNA (ceRNA) network remained poorly ...
Fulong Yu (3398372), Yan Zhang (8098), Siqi Bao (3765430), Jie Sun (74648)   +3 more
core   +1 more source

Table_2_Systematic Characterization of Circular RNA-Associated CeRNA Network Identified Novel circRNA Biomarkers in Alzheimer's Disease.XLSX [PDF]

, 2019
Alzheimer's disease (AD), a degenerative disease of the central nervous system, is the most common form of dementia in old age. The complexity and behavior of circular RNA (circRNA)-associated competing endogenous RNA (ceRNA) network remained poorly ...
Fulong Yu (3398372), Yan Zhang (8098), Siqi Bao (3765430), Jie Sun (74648)   +3 more
core   +1 more source

Study of Neuronal Apoptosis ceRNA Network in Hippocampal Sclerosis of Human Temporal Lobe Epilepsy by RNA-Seq

Frontiers in Neuroscience, 2021
Hippocampal sclerosis (HS) is one of the most common pathological type of intractable temporal lobe epilepsy (TLE), often characterized by hippocampal atrophy, neuronal apoptosis, and gliogenesis.
Shengkun Yu, Yifei Gu, Tianyu Wang, Long Mu, Haiyang Wang, Shi Yan, Aoweng Wang, Jiabin Wang, Li Liu, Hong Shen, Meng Na, Zhiguo Lin   +11 more
doaj   +1 more source

The regulation of stem cell fate and its application in neural regeneration

Interdisciplinary Medicine, EarlyView.
Regulating stem cell fate is crucial for neural regeneration. This review summarizes key physical, biological, and chemical strategies and their applications in repairing nerve injuries, providing new insights for regenerative medicine. Abstract Regulating the fate of stem cells (SCs) is a key technical problem in the field of regenerative medicine and
Yuexin He, Xingyu Chen, Minghong He, Zhe Li   +3 more
wiley   +1 more source

LnCeVar: a comprehensive database of genomic variations that disturb ceRNA network regulation [PDF]

, 2020
LnCeVar (http://www.bio-bigdata.net/LnCeVar/) is a comprehensive database that aims to provide genomic variations that disturb lncRNA-associated competing endogenous RNA (ceRNA) network regulation curated from the published literature and high-throughput
Wang, Yanxia, Ning, Shangwei, Li, Xia, Guo, Qiuyan, Fang, Ying, Zhang, Yunpeng, Shen, Weitao, Wang, Junwei, Gao, Yue, Li, Xin, Zhang, Guangmei, Wang, Peng, Shang, Shipeng, Zhi, Hui, Chen, Steven Xi   +14 more
core   +1 more source

LINC01605 Predicts the Poor Prognosis of Non‐Small Cell Lung Cancer and Promotes Chemotherapy Resistance by Regulating miR‐7111‐5p/ELK1

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Non‐small cell lung cancer (NSCLC) is characterized by high incidence, mortality, and poor patient prognosis, with chemotherapy resistance being a common challenge. This research intends to identify key molecules involved in NSCLC and elucidate the regulatory role of the LINC01605/miR‐7111‐5p/ELK1 axis in chemotherapy resistance. LINC01605 and
Fang Zhang, Zhi‐Liang Yang, Tian‐Tian Qin, Guo‐Jun Zhang, Xiang Li   +4 more
wiley   +1 more source

ceRNA network analysis reveals prognostic markers for glioblastoma

Oncology Letters, 2019
Glioblastoma (GBM) is a common aggressive cancer that originates in the brain, which has a poor prognosis. It is therefore crucial to understand its underlying genetic mechanisms in order to develop novel therapies. The present study aimed to identify some prognostic markers and candidate therapeutic targets for GBM.
Wang, Hao, Zhang, Heying, Zeng, Juan, Tan, Yonggang   +3 more
openaire   +3 more sources

Creation of the competitive endogenous RNA (ceRNA) regulatory network. [PDF]

(A) The ceRNA regulatory network included 18 DEmRNAs, 13 DEmiRNAs, and 29 DElncRNAs in PCOS and control group. DEmRNAs, DEmiRNAs, and DElncRNAs are denoted as green triangles, pink circles, and blue diamonds, respectively.
Fan Qu (4763652), Ningning Xie (12054996), Jue Zhou (11515984), Jian Xu (31545), Danqing Chen (822647), Fangfang Wang (330843)   +5 more
core   +1 more source