Results 91 to 100 of about 16,562 (192)

Evaluating putative lncRNA‐mediated ceRNA regulatory network involving miR396 and miR319 in maize leaf growth under Fusarium verticillioides infection

Annals of Applied Biology, Volume 189, Issue 1, July 2026.
The final leaf length of maize (Zea mays) was reduced due to the pathogenic fungus Fusarium verticillioides infection as a result of increased expression of miR396 in the elongation zone and decreased expression of miR319 in the mature zone of maize leaves, leading to antagonistic regulation of the expression of the GRF15 and TCP38, respectively ...
Erdem Emre Deligoz, Fatma Aydinoglu
wiley   +1 more source

Dynamic Landscapes of Long Noncoding RNAs During Early Root Development and Differentiation in Glycine max and Glycine soja

Plant, Cell &Environment, Volume 49, Issue 7, Page 3612-3625, July 2026.
ABSTRACT Soybean (Glycine max) is an important crop for its nutritional value. Its wild relative, Glycine soja, provides a valuable genetic resource for improving soybean productivity. Root development and differentiation are essential for soybean plants to take up water and nutrients, store energy and anchor themselves.
Qiaoxia Liang, Hafiz M. Rehman, Jizhou Zhang, Hon‐Ming Lam, Ting‐Fung Chan   +4 more
wiley   +1 more source

Identification of prognostic factors for intrahepatic cholangiocarcinoma using long non-coding RNAs-associated ceRNA network

Cancer Cell International, 2020
Background Accumulating amount of evidence has highlighted the important roles of long non-coding RNAs (lncRNAs) acting as competing endogenous RNAs (ceRNAs) in tumor pathogenesis.
Zhichen Kang, Lixin Guo, Zhuo Zhu, Rongfeng Qu   +3 more
doaj   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

Molecular Oncology, Volume 20, Issue 6, Page 1643-1660, June 2026.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra, Lucca Paolo Hsu Helmich, Daniel Rodrigues de Bastos, Laura Sichero, Patrícia Savio de Araujo‐Souza, Fabio Passetti, Luisa Lina Villa   +6 more
wiley   +1 more source

Whole transcriptome sequencing identifies a competitive endogenous RNA network that regulates the immunity of bladder cancer

Heliyon
Several types of non-coding RNAs such as circRNAs, lncRNAs, and miRNAs have been identified to regulate mRNAs through the mechanism known as the competitive endogenous RNA (ceRNA) network. To explore the role of the ceRNA regulatory network in the immune
Sanhe Liu, Yiqi Wang, Liqun Duan, Diansheng Cui, Kangli Deng, Zhiqiang Dong, Shaozhong Wei   +6 more
doaj   +1 more source

The hsa_circ_0070354/miR‐4322/RAB3B Axis Facilitates the Carcinogenesis and Development of Non‐Small Cell Lung Cancer (NSCLC)

Cancer Medicine, Volume 15, Issue 6, June 2026.
ABSTRACT Background Circular RNA (hsa_circ_0070354), also known as circPTPN13, was demonstrated in our previous study that it can be used as a biomarker for diagnosing non‐small cell lung cancer (NSCLC). However, the mechanism of its role in the occurrence and development of NSCLC has not been investigated.
Yuejiao Huang, Shiyi Qin, Yu Zhang, Xinliang Gu, Ming Zheng, Guojie Ling, Lei Yang, Shaoqing Ju   +7 more
wiley   +1 more source

Construction of ceRNA regulatory networks for active pulmonary tuberculosis

Scientific Reports
AbstractDelayed diagnosis in patients with pulmonary tuberculosis (PTB) often leads to serious public health problems. High throughput sequencing was used to determine the expression levels of lncRNAs, mRNAs, and miRNAs in the lesions and adjacent health lung tissues of patients with PTB.
Qifeng Li, Tao Xin, Zhigang Liu, Quan Wang, Lanhong Ma   +4 more
openaire   +3 more sources

LncRNA MIR503HG serves as a diagnostic biomarker in patients with sepsis and regulates sepsis‐induced inflammation and cardiac dysfunction

Journal of Cell Communication and Signaling, Volume 20, Issue 2, June 2026.
MIR503HG was downregulated in sepsis and sepsis‐induced cardiac dysfunction (SICD) and served as a diagnostic biomarker. Overexpression of MIR503HG attenuated myocardial injury and systemic inflammation in a septic rat model. Mechanistically, MIR503HG acted as a ceRNA by sponging miR‐497‐5p to upregulate BDNF, revealing a protective MIR503HG/miR‐497‐5p/
Pingping Qi, Minghe Jiang, Minsheng Wu, Shengkui Chen, Qile Ye, Rong Tang   +5 more
wiley   +1 more source

Synergistic Interaction Between MALAT1/miR‐30b‐5p/BAFF Axis and Inflammatory Cytokines Underlies Rituximab‐Refractory NMOSD

CNS Neuroscience &Therapeutics, Volume 32, Issue 6, June 2026.
The MALAT1/miR‐30b‐5p/BAFF axis is activated in monocytes during NMOSD onset and relapse. The MALAT1/miR‐30b‐5p/BAFF axis is activated in monocytes, thereby facilitating the release of BAFF and inflammatory cytokines (including IL‐1, IL‐6, IL‐8, and TNF‐α).
Meiqun Deng, Keyi Zeng, Wei Chen, Jing Chen, Xiaoting Lin, Lei Chen, Yuxin Yao, Hanfei Chen, Aiyu Lin   +8 more
wiley   +1 more source

Roles of long non‐coding RNAs in gestational diabetes mellitus: Mechanisms and biomarker potential

Clinical and Translational Discovery, Volume 6, Issue 3, June 2026.
Upregulated lncRNAs in GDM Some key lncRNAs (MALAT1, MEG8, SOX2OT and …) show higher expression in GDM. Downregulated lncRNAs in GDM Some key lncRNAs (HCG27, GASS, Pax AS1 and …) show lower expression in GDM. Mechanistic roles lncRNAs regulate trophoblast proliferation, insulin signalling, neonatal and offspring health and other complications related ...
Reza Kouchaki, Fateme Karimi Dermani, Ishwaree Datta, Sahar Moghbelinejad, Nematollah Gheibi, Farideh Movahed, Fatemeh Samieerad, Saeideh Gholamzadeh Khoei, Hamid Sadeghi   +8 more
wiley   +1 more source