Results 61 to 70 of about 4,440,633 (238)
BMC Medical Genomics, 2022 Background Being the most common arrhythmia in clinic, atrial fibrillation (AF) causes various comorbidities to patients such as heart failure and stroke.
Xi Chen, Xiang-Yu He, Qing Dan, Yang Li
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Frontiers in Genetics, 2021 AimsActivation of cardiac fibroblasts (CF) is crucial to cardiac fibrosis. We constructed a cardiac fibroblast-related competing endogenous RNA (ceRNA) network.
Qing-Yuan Gao +19 more
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CeRNA regulatory network in alcohol-related EC progression.
, 2022 The lncRNA–miRNA interactions, and miRNA-target gene interactions were integrated as lncRNA-miRNA-target genes interactions, and ceRNA network was visualized based on lncRNA-miRNA-target genes interactions. A. The ceRNA network constructed by the DEGs in
Ren-Dong Xiao (12878506) +5 more
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Cupid: simultaneous reconstruction of microRNA-target and ceRNA networks [PDF]
Genome Research, 2014 We introduce a method for simultaneous prediction of microRNA–target interactions and their mediated competitive endogenous RNA (ceRNA) interactions. Using high-throughput validation assays in breast cancer cell lines, we show that our integrative approach significantly improves on microRNA–target prediction accuracy as assessed by both mRNA and ...
Chiu HS +16 more
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The Functional Characterization of Epigenetically Related lncRNAs Involved in Dysregulated CeRNA–CeRNA Networks Across Eight Cancer Types [PDF]
Frontiers in Cell and Developmental Biology, 2021 Numerous studies have demonstrated that lncRNAs could compete with other RNAs to bind miRNAs, as competing endogenous RNAs (ceRNAs), to regulate each other. On the other hand, ceRNAs were found to be recurrently dysregulated in cancer status. However, limited studies considered the upstream epigenetic regulatory factors that disrupted the normal ...
Dahua Xu +11 more
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Tamoxifen resistance-related ceRNA network for breast cancer
Frontiers in Cell and Developmental Biology, 2022 Background: Tamoxifen (TMX) is one of the most widely used drugs to treat breast cancer (BC). However, acquired drug resistance is still a major obstacle to its application, rendering it crucial to explore the mechanisms of TMX resistance in BC. This aims of this study were to identify the mechanisms of TMX resistance and construct ceRNA regulatory ...
Zipeng Qiao +11 more
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Venn diagram and ceRNA network.
, 2023 A, Intersection of predicted miRNA and DEmiRNA; B, Intersection of predicted mRNA and DEmRNA; C, ceRNA network. The expression levels of these RNA molecules were indicated by different colors, with blue representing low expression and red representing ...
Qin Wu (139038) +13 more
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A Potential ceRNA Network for Neurological Damage in Preterm Infants
BioMed Research International, 2021 Objective. This study is aimed at identifying key genes involved in neurological damage in preterm infants and at determining their potential circRNA‐miRNA‐mRNA regulatory mechanisms. Methods. Differentially expressed miRNAs, mRNAs, and circRNAs were downloaded from the GEO database.
Jin Huang, Xuejing Liang, Zhenyu Cai
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Construction and Analysis of the Tumor-Specific mRNA–miRNA–lncRNA Network in Gastric Cancer
Frontiers in Pharmacology, 2020 Weighted correlation network analysis (WGCNA) is a statistical method that has been widely used in recent years to explore gene co-expression modules.
Xiaohao Zheng +8 more
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Translational Oncology, 2022 Background: Increasing numbers of studies have elucidated the role of competitive endogenous RNA (ceRNA) networks in carcinogenesis. However, the potential role of the paclitaxel-related ceRNA network in the innate mechanism and prognosis of pancreatic ...
Si Yuan Lu +9 more
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