Results 31 to 40 of about 19,790 (218)

ceRNAs in Cancer: Mechanism and Functions in a Comprehensive Regulatory Network [PDF]

Journal of Oncology, 2021
Noncoding RNAs have been shown with powerful ability in post-transcriptional regulation, enabling intertwined RNA crosstalk and global molecular interaction in a large amount of dysfunctional conditions including cancer. Competing endogenous RNAs (ceRNAs) are those competitively binding with shared microRNAs (miRNAs), freeing their counterparts from ...
Ni Yang, Kuo Liu, Mengxuan Yang, Xiang Gao   +3 more
openaire   +2 more sources

Image1_Integrated analysis of circRNA-associated ceRNA network in ischemic stroke.JPEG [PDF]

, 2023
Introduction: Stroke, of which ischemic stroke (IS) is the major type, is the second leading cause of disability and death worldwide. Circular RNAs (circRNAs) are reported to play important role in the physiology and pathology of IS.
Maiqiu Wang (11821886), Lei Zhang (38117), Die Hu (160944), Yifeng Zhou (129920), Rongli Fan (2367391), Huilin Zheng (1774843)   +5 more
core   +1 more source

Comprehensive ceRNA network for MACF1 regulates osteoblast proliferation

BMC Genomics, 2022
Abstract Background Previous studies have shown that microtubule actin crosslinking factor 1 (MACF1) can regulate osteoblast proliferation and differentiation through non-coding RNA (ncRNA) in bone-forming osteoblasts.
Shanfeng Jiang, Chong Yin, Kai Dang, Wenjuan Zhang, Ying Huai, Airong Qian   +5 more
openaire   +3 more sources

PPI network and visualization of ceRNA network. [PDF]

, 2021
(A) STRING database was used to analyze the PPI network of 193 prognostic genes, and each node represented a distinct gene. (B) MCC algorithm was used to recognize hub-genes from PPI network, red and yellow nodes represented 8 hub-genes; (C, D) The ...
Zeng Fen (11250416), Jingrong Lin (180903), Yingming Chu (11250413), Qianyi Chen (6725840), Yuankuan Jiang (11250419), Nan Yang (305078), Shifeng Fang (3707584), Xueying Shi (11250410), Shilin Xia (250469), Jingyuan Zheng (7022564)   +9 more
core   +1 more source

Competing Endogenous RNA Network Analysis Reveals Pivotal ceRNAs in Adrenocortical Carcinoma

Frontiers in Endocrinology, 2019
Objective: To construct ceRNA network and identify pivotal competing endogenous RNAs (ceRNAs) in adrenocortical carcinoma (ACC) using ceRNA network analysis.Methods: The RNA sequencing expression data of 77 ACCs in TCGA were obtained from GEPIA.
Weiwei Liang, Fangfang Sun
doaj   +1 more source

ceRNAshiny: An Interactive R/Shiny App for Identification and Analysis of ceRNA Regulation

Frontiers in Molecular Biosciences, 2022
The competing endogenous RNA (ceRNA) network is a newly discovered post-transcriptional regulation that controls both physiological and pathological progresses. Increasing research studies have been pivoted on this theory to explore the function of novel
Yueqiang Song, Jia Li, Yiming Mao, Xi Zhang, Xi Zhang   +4 more
doaj   +1 more source

Age-related ceRNA networks in adult Drosophila ageing

Frontiers in Genetics, 2023
As Drosophila is an extensively used genetic model system, understanding of its regulatory networks has great significance in revealing the genetic mechanisms of ageing and human diseases. Competing endogenous RNA (ceRNA)-mediated regulation is an important mechanism by which circular RNAs (circRNAs) and long non-coding RNAs (lncRNAs) regulate ageing ...
Deying Yang, Deying Yang, Feng Xiao, Jiamei Li, Siqi Wang, Xiaolan Fan, Xiaolan Fan, Qingyong Ni, Qingyong Ni, Yan Li, Yan Li, Mingwang Zhang, Mingwang Zhang, Taiming Yan, Mingyao Yang, Mingyao Yang, Zhi He   +16 more
openaire   +3 more sources

Table1_Integrated analysis of circRNA-associated ceRNA network in ischemic stroke.XLSX [PDF]

, 2023
Introduction: Stroke, of which ischemic stroke (IS) is the major type, is the second leading cause of disability and death worldwide. Circular RNAs (circRNAs) are reported to play important role in the physiology and pathology of IS.
Maiqiu Wang (11821886), Die Hu, Lei Zhang (38117), Huilin Zheng, Yifeng Zhou, Die Hu (160944), Yifeng Zhou (129920), Lei Zhang, Rongli Fan (2367391), Huilin Zheng (1774843), Rongli Fan, Maiqiu Wang   +11 more
core   +1 more source

STARD13-correlated ceRNA network-directed inhibition on YAP/TAZ activity suppresses stemness of breast cancer via co-regulating Hippo and Rho-GTPase/F-actin signaling

Journal of Hematology & Oncology, 2018
Background Targeting cancer stem cells is critical for suppressing cancer progression and recurrence. Finding novel markers or related pathways could help eradicate or diagnose cancer in clinic.
Lufeng Zheng, Chenxi Xiang, Xiaoman Li, Qianqian Guo, Lanlan Gao, Haiwei Ni, Yufeng Xia, Tao Xi   +7 more
doaj   +1 more source

Construction and function analysis of the LncRNA-miRNA-mRNA competing endogenous RNA network in autoimmune hepatitis

BMC Medical Genomics, 2022
Research Highlights It was the first time to explore the disorder of ceRNA network involved in the pathogenesis of AIH. The co-expression relationship between the differentially expressed lncRNAs, miRNAs and mRNAs were predicted. The potential biological
Zhencheng Li, Ying Liu, Yiwen Hou, Zhurong Li, Chen Chen, Huiqin Hao, Yang Liu   +6 more
doaj   +1 more source