Results 31 to 40 of about 4,440,633 (238)
lncRNA-mediated ceRNA network in bladder cancer
Non-coding RNA Research, 2023 Bladder cancer is a common disease associated with high rates of morbidity and mortality. Although immunotherapy approaches such as adoptive T-cell therapy and immune checkpoint blockade have been investigated for the treatment of bladder cancer, their off-target effects and ability to affect only single targets have led to clinical outcomes that are ...
Kun Li, Tongyue Yao, Ziqiang Wang
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ceRNAs in Cancer: Mechanism and Functions in a Comprehensive Regulatory Network [PDF]
Journal of Oncology, 2021 Noncoding RNAs have been shown with powerful ability in post-transcriptional regulation, enabling intertwined RNA crosstalk and global molecular interaction in a large amount of dysfunctional conditions including cancer. Competing endogenous RNAs (ceRNAs) are those competitively binding with shared microRNAs (miRNAs), freeing their counterparts from ...
Ni Yang +3 more
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Cancer Cell International, 2020 Background Glioblastoma multiforme (GBM) is the most seriously brain tumor with extremely poor prognosis. Recent research has demonstrated that competitive endogenous RNA (ceRNA) network which long noncoding RNAs (lncRNAs) act as microRNA (miRNA) sponges
Xiaolong Zhu +5 more
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Regulation of Long Non-coding RNA KCNQ1OT1 Network in Colorectal Cancer Immunity
Frontiers in Genetics, 2021 Over the past few decades, researchers have become aware of the importance of non-coding RNA, which makes up the vast majority of the transcriptome.
Junjie Liu +3 more
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Scientific Reports, 2021 To identify the prognostic biomarker of the competitive endogenous RNA (ceRNA) and explore the tumor infiltrating immune cells (TIICs) which might be the potential prognostic factors in lung adenocarcinoma.
Wenjie Chen +7 more
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Comprehensive analysis of ceRNA network of ERCC4 in colorectal cancer
PeerJ, 2021 Objective ERCC4 is one of the most significant molecules of Nucleotide Excision Repair (NER), which has been researched due to its high expression in colorectal cancer (CRC). This study aimed to find out the ceRNA (competitive endogenous RNA) network of ERCC4 in CRC.
Hu, Huixin +5 more
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Competing Endogenous RNA Network Analysis Reveals Pivotal ceRNAs in Adrenocortical Carcinoma
Frontiers in Endocrinology, 2019 Objective: To construct ceRNA network and identify pivotal competing endogenous RNAs (ceRNAs) in adrenocortical carcinoma (ACC) using ceRNA network analysis.Methods: The RNA sequencing expression data of 77 ACCs in TCGA were obtained from GEPIA.
Weiwei Liang, Fangfang Sun
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ceRNAshiny: An Interactive R/Shiny App for Identification and Analysis of ceRNA Regulation
Frontiers in Molecular Biosciences, 2022 The competing endogenous RNA (ceRNA) network is a newly discovered post-transcriptional regulation that controls both physiological and pathological progresses. Increasing research studies have been pivoted on this theory to explore the function of novel
Yueqiang Song +4 more
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The regulatory mechanism of LncRNA-mediated ceRNA network in osteosarcoma
Scientific Reports, 2022 AbstractAberrantly expressed lncRNAs have been reported to be closely related to the oncogenesis and development of osteosarcoma. However, the role of a dysregulated lncRNA-miRNA-mRNA network in osteosarcoma in the same individual needs to be further investigated. Whole transcriptome sequencing was performed on the tumour tissues and matched paratumour
Chengsen Lin +10 more
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Journal of Hematology & Oncology, 2018 Background Targeting cancer stem cells is critical for suppressing cancer progression and recurrence. Finding novel markers or related pathways could help eradicate or diagnose cancer in clinic.
Lufeng Zheng +7 more
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