Results 11 to 20 of about 4,440,633 (238)

Prognostic Roles of ceRNA Network-Based Signatures in Gastrointestinal Cancers [PDF]

open access: yesFrontiers in Oncology, 2022
Gastrointestinal cancers (GICs) are high-incidence malignant tumors that seriously threaten human health around the world. Their complexity and heterogeneity make the classic staging system insufficient to guide patient management.
Xin Qi   +6 more
doaj   +4 more sources

Construction of a ceRNA Network Related to Rheumatoid Arthritis

open access: yesGenes, 2022
(1) Background: Rheumatoid arthritis (RA) is a common systemic autoimmune disease affecting many people and has an unclear and complicated physiological mechanism.
Nanzhen Kuang, Zhanya Huang
core   +3 more sources

The immune-related ceRNA network in prognosis of cervical cancer [PDF]

open access: yesAsian Pacific Journal of Cancer Prevention, 2022
Background: Immunotherapy is gaining attention and it is being included as one of the treatment strategies for cancer patients. However, the molecular mechanisms of immune-related genes and their affinity for cervical cancer progression remain unclear ...
Bose, Mayilvahanan   +2 more
core   +3 more sources

Uncovering the ceRNA network and DNA methylation associated with gene expression in nasopharyngeal carcinoma

open access: yesBMC Medical Genomics, 2023
Objective This study aimed to uncover abnormally expressed genes regulated by competitive endogenous RNA (ceRNA) and DNA methylation nasopharyngeal carcinoma and to validate the role of lncRNAs in the ceRNA network on nasopharyngeal carcinoma progression.
Ting Zhang   +5 more
doaj   +2 more sources

Identifying a Comprehensive ceRNA Network to Reveal Novel Targets for the Pathogenesis of Parkinson's Disease

open access: yesFrontiers in Neurology, 2020
Parkinson's disease (PD) is the second commonest progressive neurodegenerative disease worldwide. Increasing evidence reveals that non-coding RNAs play roles in the pathophysiological process of PD.
Xi Zhang   +8 more
doaj   +3 more sources

Systematic Characterization of Circular RNA-Associated CeRNA Network Identified Novel circRNA Biomarkers in Alzheimer's Disease

open access: yesFrontiers in Bioengineering and Biotechnology, 2019
Alzheimer's disease (AD), a degenerative disease of the central nervous system, is the most common form of dementia in old age. The complexity and behavior of circular RNA (circRNA)-associated competing endogenous RNA (ceRNA) network remained poorly ...
Yan Zhang, Fulong Yu, Siqi Bao, Jie Sun
doaj   +3 more sources

Comprehensive analysis of lncRNA-miRNA-mRNA ceRNA network in ischemic stroke

open access: yesHeliyon
Objective: Competitive endogenous RNA (ceRNA) networks have uncovered a novel mode of RNA interaction, and are implicated in various biological processes and the pathogenesis of IS.
Lin Cheng, Yun Zhao, Hong Ke
doaj   +3 more sources

Identification and validation of a novel glycolysis-related ceRNA network for sepsis-induced cardiomyopathy [PDF]

open access: yesFrontiers in Medicine
PurposeSepsis-induced cardiomyopathy (SIC) is a major life-threatening condition in critically infected patients. Early diagnosis and intervention are important to improve patient prognosis.
Lulu Cheng   +7 more
doaj   +2 more sources

Deciphering the rules of ceRNA networks [PDF]

open access: yesProceedings of the National Academy of Sciences, 2013
Recent theoretical and experimental studies have shed light on the complex network of interactions among the multiple classes of RNA within the cell. Although much of the focus over the past decade has been on the mechanisms by which microRNAs (miRNA) regulate the stability and translation of messenger RNAs (mRNAs), more recently it has come to light ...
Marcella, Cesana, George Q, Daley
openaire   +4 more sources

Construction of ceRNA regulatory networks for osteoporosis

open access: yesMolecular Medicine Reports, 2023
Osteoporosis increases the risk of fracture. Improving the diagnosis and treatment of osteoporosis has clinical applications. The differentially expressed genes (DEcircRs, DEmRs, DEmiRs) of osteoporotic patients and controls were analyzed using the GEO database, and enrichment analysis of DEmRs was performed. circRNAs and mRNAs, which were predicted to
Chen, Hongtao   +5 more
openaire   +2 more sources

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