Results 11 to 20 of about 16,562 (192)
Journal of Orthopaedic Surgery and Research, 2021 Background This study was aimed to discover more biomarkers associated with spinal cord injury (SCI) by constructing a competing endogenous RNA (ceRNA) network.
Chongcheng Gong, Lin Liu, Yang Shen
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Interactions between Distant ceRNAs in Regulatory Networks [PDF]
Biophysical Journal, 2014 Competing endogenous RNAs (ceRNAs) were recently introduced as RNA transcripts that affect each other's expression level through competition for their microRNA (miRNA) coregulators. This stems from the bidirectional effects between miRNAs and their target RNAs, where a change in the expression level of one target affects the level of the miRNA ...
Mor Nitzan +4 more
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Development of Ferroptosis-Associated ceRNA Network in Periodontitis
International Dental Journal, 2023 Periodontitis is a chronic inflammatory illness that may lead to tooth loosening and even loss, and its pathogenesis is not fully understood. Ferroptosis is an iron-dependent, regulated cell death. The present study aims to find the key ferroptosis-related genes (FRGs) in periodontitis and develop an mRNA-miRNA-lncRNA network to deeply explore the ...
Churen Zhang +3 more
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Heliyon, 2023 Accumulating evidence showed that competing endogenous RNA (ceRNA) mechanism plays a pivotal role in salt sensitivity of blood pressure (SSBP). We constructed a ceRNA network based on SSBP-related differently expressed lncRNAs (2), mRNAs (73) and miRNAs (
Wenjuan Peng +8 more
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Comprehensive analysis of the ceRNA network in coronary artery disease [PDF]
Scientific Reports, 2021 AbstractWith the rapid aging of the population, coronary artery disease (CAD) has become one of the most fatal chronic diseases. However, the genetic mechanism of CAD is still unclear. The purpose of this study is to construct the lncRNA-miRNA-mRNA regulatory network for CAD diseases and systematically identify differentially expressed genes in ...
Weikang Bian +8 more
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Frontiers in Oncology, 2022 Stomach adenocarcinoma (STAD) is one of the most malignant cancers that endanger human health. There is growing evidence that competitive endogenous RNA (ceRNA) regulatory networks play an important role in various human tumors.
Zhihong Huang +12 more
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ceRNAs in Cancer: Mechanism and Functions in a Comprehensive Regulatory Network [PDF]
Journal of Oncology, 2021 Noncoding RNAs have been shown with powerful ability in post-transcriptional regulation, enabling intertwined RNA crosstalk and global molecular interaction in a large amount of dysfunctional conditions including cancer. Competing endogenous RNAs (ceRNAs) are those competitively binding with shared microRNAs (miRNAs), freeing their counterparts from ...
Ni Yang +3 more
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Frontiers in Neurology, 2020 Parkinson's disease (PD) is the second commonest progressive neurodegenerative disease worldwide. Increasing evidence reveals that non-coding RNAs play roles in the pathophysiological process of PD.
Xi Zhang +8 more
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Cancer Cell International, 2020 Background Glioblastoma multiforme (GBM) is the most seriously brain tumor with extremely poor prognosis. Recent research has demonstrated that competitive endogenous RNA (ceRNA) network which long noncoding RNAs (lncRNAs) act as microRNA (miRNA) sponges
Xiaolong Zhu +5 more
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Prognostic Roles of ceRNA Network-Based Signatures in Gastrointestinal Cancers
Frontiers in Oncology, 2022 Gastrointestinal cancers (GICs) are high-incidence malignant tumors that seriously threaten human health around the world. Their complexity and heterogeneity make the classic staging system insufficient to guide patient management.
Xin Qi +6 more
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