Results 241 to 250 of about 28,713 (267)

The new function of circRNA: translation

Clinical and Translational Oncology, 2020
Circular RNAs (circRNAs) have been considered a special class of non-coding RNAs without 5' caps and 3' tails which are covalently closed RNA molecules generated by back splicing of mRNA. For a long time, circRNAs have been considered to be directly involved in various biological processes as functional RNA.
Y. Shi, X. Jia, J. Xu
openaire   +2 more sources

Role of lncRNAs and circRNAs in epilepsy

Ageing Research Reviews, 2022
Epilepsy is a chronic disorder of with a high prevalence and extensive health burden in almost all age groups of the population. This condition is resulted from disturbance in the balance between excitatory and inhibitory factors in the brain. Genetic elements that affect synaptic connectivity, receptors functions or ion channels have been shown to ...
Soudeh Ghafouri-Fard, Bashdar Mahmud Hussen, Elena Jamali, Wojciech Branicki, Mohammad Taheri, Nader Akbari Dilmaghani   +5 more
openaire   +2 more sources

PWCDA: Path Weighted Method for Predicting circRNA-Disease Associations

International Journal of Molecular Sciences, 2018
CircRNAs have particular biological structure and have proven to play important roles in diseases. It is time-consuming and costly to identify circRNA-disease associations by biological experiments.
Xiujuan Lei, Luonan Chen, Fang-Xiang Wu   +2 more
exaly   +2 more sources

CircRNA Synthesis and Applications

Circular RNA (circRNA) is becoming an increasingly popular field of study and topic of interest. With that, there is a renewed and heightened interest in generating circular RNA for both research and clinical use. CircRNA generation began in the 1990s using in vitro chemical ligation and has since expanded out to include in vitro enzymatic synthesis ...
Adam, Greasley, Shuailong, Li, KeXiang, Liu, Xiufen, Zheng   +3 more
openaire   +2 more sources

CRISPR–Cas13 targets circRNAs

Nature Reviews Genetics, 2020
The CRISPR–Cas13 system can be used to knock down circular RNAs (circRNAs) without any impact on related mRNAs, reports a study in Nature Methods.
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Circular RNAs (circRNAs) in cancer

Cancer Letters, 2018
Circular RNAs (circRNAs) are a class of non-coding RNAs that do not have 5' end caps or 3' end poly (A) tails. There are more than one hundred thousand genes that encode circRNAs. Clinical data show that there are differences in the expression of circRNAs in a variety of diseases, including cancer, suggesting that circRNA has a regulatory effect on ...
Ruoyu Zhou, Yuwei Wu, Wenxi Wang, Wenjia Su, Yicong Liu, Yumin Wang, Chunmei Fan, Xiaoling Li, Guiyuan Li, Yong Li, Wei Xiong, Zhaoyang Zeng   +11 more
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CircRNAs in cancer therapy tolerance

Clinica Chimica Acta
The rapidly expanding field of circular RNA (circ-RNA) research has opened new avenues in cancer diagnostics and treatment, highlighting the role of serum circRNAs as potential biomarkers for assessing tumor therapy resistance. This review comprehensively compiles existing knowledge regarding the biogenesis, function, and clinical relevance of circRNAs,
Miao He, Yunyan Pan, Chongge You, Hongwei Gao   +3 more
openaire   +2 more sources

Exosome‐Based Mitochondrial Delivery of circRNA mSCAR Alleviates Sepsis by Orchestrating Macrophage Activation

Advanced Science, 2023
Xuekang Yang
exaly  

CircRNA: a rising star in plant biology

Journal of Genetics and Genomics, 2022
Mingqiu Dai
exaly  

iCircDA-MF: identification of circRNA-disease associations based on matrix factorization

Briefings in Bioinformatics, 2020
Hang Wei
exaly