Results 151 to 160 of about 167,695 (329)

Cryo‐EM Structures Reveal the Molecular Basis of Asymmetric Allosteric Activation by MMOB in the Hydroxylase of Soluble Methane Monooxygenase

open access: yesAdvanced Science, EarlyView.
Cryo‐EM analysis reveals an asymmetric MMOH–MMOB complex with distinct protomers, where MMOB binding triggers structural rearrangements from the surface to the active site. This conformational asymmetry shortens the Fe···Fe distance to 2.7 Å in one protomer, forming a geometry suitable for O2 activation and supporting a sequential catalytic mechanism ...
Yunha Hwang   +9 more
wiley   +1 more source

Chromatographic Enantiomer Separation, Circular Dichroism Spectrum, and Absolute Configuration of the 7-Methoxycoumarin syn Head-to-Tail Dimer. [PDF]

open access: bronze, 1991
Tihamér Hargitai   +7 more
openalex   +1 more source

A Mini‐Spidroin Forms High‐Performance Artificial Spider Silk via Edge‐Cysteine–Locked β‐Sheet Assembly

open access: yesAdvanced Science, EarlyView.
Cysteine‐engineered mini‐spidroins (∼33 kDa) undergo phosphate‐induced liquid–liquid phase separation (LLPS), where disulfide bonds lock partially aligned polyA segments. Subsequent microfluidic spinning promotes directional β‐sheet crystallization, producing fibers with 531 MPa strength and 182 MJ/m3 toughness.
Min Li   +10 more
wiley   +1 more source

AI‐Based D‐Amino Acid Substitution for Optimizing Antimicrobial Peptides to Treat Multidrug‐Resistant Bacterial Infection

open access: yesAdvanced Science, EarlyView.
This study constructed the first D‐amino acid antimicrobial peptide dataset and developed an AI model for efficient screening of substitution sites, with 80% of candidate peptides showing enhanced activity. The lead peptide dR2‐1 demonstrated potent antimicrobial activity in vitro and in vivo, high stability, and low toxicity.
Yinuo Zhao   +14 more
wiley   +1 more source

Distinct spectral response in M-edge magnetic circular dichroism [PDF]

open access: green, 2020
Kelvin Yao   +10 more
openalex   +1 more source

Substituent‐Based Modulation of Self‐Assembly and Immunogenicity of Amphipathic Peptides

open access: yesAdvanced Science, EarlyView.
This study systematically investigates how positional and subtle changes, such as substituents on the phenyl ring attached to short amphipathic peptides, influence their self‐assembly, fibril morphology, and immunogenic responses. ABSTRACT Self‐assembled peptide‐based biomaterials provide versatile platforms for biomedical uses, featuring customizable ...
Anirban Das   +13 more
wiley   +1 more source

Optical circular dichroism of single-wall carbon nanotubes [PDF]

open access: green, 2006
A. Sánchez-Castillo   +2 more
openalex   +1 more source

Local‐to‐Nonlocal Second‐Harmonic Generation from Electrically Tunable Intersubband Polaritonic Metasurfaces

open access: yesAdvanced Science, EarlyView.
A local‐to‐nonlocal SHG process is demonstrated on an electrically tunable metasurface, combining an LSPR at the FF with a TM‐GMR at the SH to achieve independent dual tunability. Through modal‐overlap engineering of the proposed scheme, a high‐χ(2) MQW meta‐atom delivers strong nonlinearity while achieving 2‐DoF SH control with minimal trade‐offs ...
Jaesung Kim   +5 more
wiley   +1 more source

Home - About - Disclaimer - Privacy