Results 31 to 40 of about 251,975 (292)

In vitro study of drug-protein interaction using electronic absorption, fluorescence, and circular dichroism spectroscopy [PDF]

Archives of Razi Institute, 2016
In the near future, design of a new generation of drugs targeting proteins will be required. Considering the complex bond between the drug and protein, the structure and stability of the target protein should be considered.
F. Attar, S. Khavari-Nejad
doaj   +1 more source

Presenilin-1-Derived Circular RNAs: Neglected Epigenetic Regulators with Various Functions in Alzheimer’s Disease

Biomolecules, 2023
The presenilin-1 (PSEN1) gene is crucial in developing Alzheimer’s disease (AD), a progressive neurodegenerative disorder and the most common cause of dementia.
Nima Sanadgol, Javad Amini, Cordian Beyer, Adib Zendedel   +3 more
doaj   +1 more source

CPDB: a database of circular permutation in proteins [PDF]

Nucleic Acids Research, 2008
Circular permutation (CP) in a protein can be considered as if its sequence were circularized followed by a creation of termini at a new location. Since the first observation of CP in 1979, a substantial number of studies have concluded that circular permutants (CPs) usually retain native structures and functions, sometimes with increased stability or ...
Wei-Cheng Lo, Chi-Ching Lee, Che-Yu Lee, Ping-Chiang Lyu   +3 more
openaire   +2 more sources

Identification of compounds with regenerative effects in the mucus of the garden snail Cornu aspersum

Biotechnology & Biotechnological Equipment
Snail mucus is a complex multicomponent mixture of proteoglycans, glycosaminoglycans, enzymes, hyaluronic acid, proteins, antimicrobial peptides, amino acids and metal ions.
Momchil Kermedchiev, Maya Guncheva, Angelina Kosateva, Maria Todorova, Valentina Lyubomirova, Lyudmila Velkova, Pavlina Dolashka, Aleksandаr Dolashki   +7 more
doaj   +1 more source

CircRNAs: role in human diseases and potential use as biomarkers

Cell Death and Disease, 2021
Circular RNAs (circRNAs) are a class of endogenous RNAs characterized by a covalent loop structure. In comparison to other types of RNAs, the abundance of circRNAs is relatively low but due to the circular configuration, their stability is very high.
Lorena Verduci, Emilio Tarcitano, Sabrina Strano, Yosef Yarden, Giovanni Blandino   +4 more
doaj   +1 more source

DichroMatch: a website for similarity searching of circular dichroism spectra

, 2012
Circular dichroism (CD) spectroscopy is a widely used method for examining the structure, folding and conformational changes of proteins. A new online CD analysis server (DichroMatch) has been developed for identifying proteins with similar spectral ...
Klose, D.P., B. A. Wallace, Wallace, Bonnie A., Janes, R.W., Robert W. Janes, D. P. Klose   +5 more
core   +1 more source

Recent development of urinary biomarkers for bladder cancer diagnosis and monitoring

Clinical and Translational Discovery, 2023
Urine‐based liquid biopsy has emerged as a non‐invasive and effective tool for early screening and diagnosis of bladder cancer. This review provides a comprehensive overview of the current urine‐based biomarkers and methods for the detection and ...
Yuchen Zeng, Anqi Wang, Wei Lv, Qingqing Wang, Shiqi Jiang, Xiaoguang Pan, Fei Wang, Huanming Yang, Lars Bolund, Chunhua Lin, Peng Han, Yonglun Luo   +11 more
doaj   +1 more source

Conformational effects on the Circular Dichroism of Human Carbonic Anhydrase II: a multilevel computational study

, 2013
Circular Dichroism (CD) spectroscopy is a powerful method for investigating conformational changes in proteins and therefore has numerous applications in structural and molecular biology. Here a computational investigation of the CD spectrum of the Human
Uno Carlsson, Kia Balali-Mood (210078), Karabencheva-Christova, Tatyana G, Balali-Mood Kia, Gary W. Black (382116), Black Gary W., Carlsson, Uno,, Kia Balali-Mood, Christov, Christo Z., Carlsson, Uno, Balali-Mood, Kia,, Christo Z Christov, Christov, Christo, Christov Christo Z., Karabencheva-Christova, Tatyana G,, Tatyana G. Karabencheva-Christova (382114), Uno Carlsson (382115), Black, Gary W., Karabencheva-Christova, Tatyana, Christo Z. Christov (382117), Tatyana G Karabencheva-Christova, Balali-Mood, Kia, Karabencheva-Christova Tatyana G., Carlsson Uno, Black, Gary W.,, Gary W Black, Black, Gary, Christov, Christo Z.,   +27 more
core   +1 more source

PCDDB: the Protein Circular Dichroism Data Bank, a repository for circular dichroism spectral and metadata

, 2010
The Protein Circular Dichroism Data Bank (PCDDB) is a public repository that archives and freely distributes circular dichroism (CD) and synchrotron radiation CD (SRCD) spectral data and their associated experimental metadata.
Klose, D.P., Benjamin Woollett, B. A. Wallace, Woollett, Benjamin, Janes, R.W., Wallace, Bonnie A., Robert W. Janes, Lee Whitmore, Andrew John Miles, Whitmore, Lee, Miles, Andrew J., D. P. Klose   +11 more
core   +1 more source

Latherin: a surfactant protein of horse sweat and saliva [PDF]

, 2009
Horses are unusual in producing protein-rich sweat for thermoregulation, a major component of which is latherin, a highly surface-active, non-glycosylated protein.
Douglas L Bovell, Cooper, Alan, Malcolm W Kennedy, Lu Jian R., Zhao Xiubo, McDonald, R.E., John G Beeley, Fleming, R.I., Lu, J.R., Lu, Jian R., Beeley, John G., Xiubo Zhao, Lu, Jian R.; id_orcid, Flemming, Rachel I., Cooper Alan, Fleming Rachel I., Beeley, J.G., Fleming, Rachel I., Kennedy, M.W., Zhao, Xiubo, Bovell, Douglas L., McDonald Rhona E., Bovell Douglas L., Alan Cooper, Zhao, X., Cooper, A., Rhona E McDonald, Jian R Lu, Beeley John G., Kennedy, Malcolm W., McDonald, Rhona E., Bovell, D.L., Kennedy Malcolm W., Rachel I Fleming   +33 more
core   +1 more source