Results 251 to 260 of about 233,958 (293)

A Dual‐Phase Exosomal Nanotherapy Enhances Continual Efferocytosis by Coordinating Checkpoint Inhibition and Metabolic Reprogramming in Atherosclerosis

open access: yesAdvanced Science, EarlyView.
Here we developed Am@SExo, a dual‐functional engineered exosome that coordinates CD47–SIRPα checkpoint blockade with Arg1 mRNA–mediated metabolic reprogramming. Surface SIRPα promotes recognition of apoptotic cells and plaque targeting, while Arg1 expression enhances arginine–ornithine metabolism, Rac1 activation, and actin remodeling in macrophages ...
Danwen Zheng   +17 more
wiley   +1 more source

Senolytic Treatment With Fisetin Reverses Age-Related Endothelial Dysfunction Partially Mediated by SASP Factor CXCL12. [PDF]

open access: yesAging Cell
Mahoney SA   +14 more
europepmc   +1 more source

Endothelial Integrin-Linked Kinase (ILK) Deficiency Promotes Endothelial Activation and Cardiovascular Dysfunction via Receptor Interacting Protein Kinase-1 (RIPK1) Enriched-Extracellular Vesicle Signalling. [PDF]

open access: yesJ Extracell Vesicles
Cook-Calvete A   +9 more
europepmc   +1 more source

Immunopathogenesis of antibody-mediated rejection in liver transplantation. [PDF]

open access: yesFront Immunol
Luo B   +5 more
europepmc   +1 more source

Endothelial Cells and the Cerebral Circulation

Comprehensive Physiology, 2022
Abstract Endothelial cells form the innermost layer of all blood vessels and are the only vascular component that remains throughout all vascular segments. The cerebral vasculature has several unique properties not found in the peripheral circulation; this requires that the cerebral endothelium be considered as a ...
Theresa A, Lansdell   +2 more
openaire   +2 more sources

Circulating endothelial cells

Thrombosis and Haemostasis, 2005
SummaryRecent research has recognised new populations of non-hematopoïetic cells in the blood. One of these, circulating endothelial cells (CECs), often defined by the expression of membrane glycoprotein CD146, are rarely found in the blood in health, but raised numbers are present in a wide variety of human conditions, including inflammatory, immune ...
Francesco Bertolini   +2 more
exaly   +3 more sources

Circulating endothelial cells in Kawasaki disease

open access: yesClinical and Experimental Immunology, 2003
summary Recent reports have demonstrated that circulating endothelial cells (CECs) are observed in several diseases with vascular injury. Because Kawasaki disease (KD) is one type of systemic vasculitis, we hypothesized that an increased number of CECs may be associated with the appearance of complicated coronary artery lesions (CAL). In
I Sekine
exaly   +4 more sources

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