Results 31 to 40 of about 223,621 (247)
Bio-Protocol, 2016 Hematogenous metastasis is a primary cause of mortality from metastatic cancer. The shear-resistant adhesion of circulating tumor cells to the vascular endothelial cell surface under blood flow is an essential step in cell extravasation and further ...
Shin-Ae Kang +2 more
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Caspases and p38 MAPK regulate endothelial cell adhesiveness for mesenchymal stem cells. [PDF]
PLoS ONE, 2013 Mesenchymal stem cells natively circulating or delivered into the blood stream home to sites of injury. The mechanism of mesenchymal stem cell homing to sites of injury is poorly understood.
Irina A Potapova +2 more
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Circulating endothelial cells demonstrate an attenuation of endothelial damage by minimizing the extracorporeal circulation [PDF]
The Journal of Thoracic and Cardiovascular Surgery, 2006 Detachment of endothelial cells may represent serious injury of the endothelium after cardiopulmonary bypass. We investigated whether the extent of endothelial injury is related to the type of cardiopulmonary bypass system used (conventional or minimized) and determined circulating endothelial cells as well as von Willebrand factor and soluble ...
Skrabal, Christian A. +6 more
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Circulating Endothelial Cells in Vasculitis and Transplantation [PDF]
Pathophysiology of Haemostasis and Thrombosis, 2003 Damage to microvascular endothelial cells is the hallmark of small-vessel vasculitis. Based on the histology, however, an intriguing question has long been unanswered: Given that cells undergo detachment from the basement, what happens to these cells and can we detect them in peripheral blood? Moreover, it seemed reasonable to assume that the number of
openaire +2 more sources
Circulating Endothelial Cells and Endothelial Progenitor Cells in Obstructive Sleep Apnea [PDF]
Lung, 2008 Increased circulating endothelial cells (CECs) have been observed in patients with vascular injury associated with acute myocardial infarction, pulmonary hypertension, and congestive heart failure. Decreased circulating endothelial progenitor cells (EPCs) have been observed in patients with risk factors for cardiovascular disease.
Kevin, Martin +4 more
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Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Research Journal of Life Science, 2018 The administration of deoxy-corticosterone acetate (DOCA)-salt can induce oxidative stress leading to decrease the bioavailability of nitric oxide (NO), increase senescence of circulating endothelial progenitor cells (EPCs), thus contributing to ...
Dian Nugrahenny +2 more
doaj +1 more source
Maximal Exercise Improves the Levels of Endothelial Progenitor Cells in Heart Failure Patients
Current Issues in Molecular Biology, 2023 The impact of exercise on the levels of endothelial progenitor cells (EPCs), a marker of endothelial repair and angiogenesis, and circulating endothelial cells (CECs), an indicator of endothelial damage, in heart failure patients is largely unknown. This
Suiane Cavalcante +10 more
doaj +1 more source
Detection of circulating endothelial cells and endothelial progenitor cells by flow cytometry [PDF]
Cytometry Part B: Clinical Cytometry, 2005 The finding of angiogenic and vasculogenic cells in the peripheral circulation may have profound effects on the course of a variety of diseases ranging from cancer to cardiovascular disease. These cells are ascribed to be endothelial in nature and are generally referred to as circulating endothelial cells if mature or as endothelial progenitor cells if
Sameena S, Khan +2 more
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Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source