Double-Stranded RNA Attenuates the Barrier Function of Human Pulmonary Artery Endothelial Cells [PDF]
Circulating RNA may result from excessive cell damage or acute viral infection and can interact with vascular endothelial cells. Despite the obvious clinical implications associated with the presence of circulating RNA, its pathological effects on ...
Heinemann, Akos +46 more
core +1 more source
Profoundly reduced neovascularization capacity of bone marrow mononuclear cells derived from patients with chronic ischemic heart disease [PDF]
Background— Cell therapy with bone marrow–derived stem/progenitor cells is a novel option for improving neovascularization and cardiac function in ischemic heart disease.
Dimmeler, S +8 more
core +1 more source
Circulating endothelial cells are increased in chronic myeloid leukemia blast crisis [PDF]
We measured circulating endothelial precursor cells (EPCs), activated circulating endothelial cells (aCECs), and mature circulating endothelial cells (mCECs) using four-color multiparametric flow cytometry in the peripheral blood of 84 chronic myeloid ...
C.R.T. Godoy +5 more
doaj +4 more sources
Circulating progenitor cell count for cardiovascular risk stratification: a pooled analysis [PDF]
Background: Circulating progenitor cells (CPC) contribute to the homeostasis of the vessel wall, and a reduced CPC count predicts cardiovascular morbidity and mortality.
Zeiher Andreas M. +46 more
core +1 more source
Hematogenous metastasis is a primary cause of mortality from metastatic cancer. The shear-resistant adhesion of circulating tumor cells to the vascular endothelial cell surface under blood flow is an essential step in cell extravasation and further ...
Shin-Ae Kang +2 more
doaj +1 more source
Caspases and p38 MAPK regulate endothelial cell adhesiveness for mesenchymal stem cells. [PDF]
Mesenchymal stem cells natively circulating or delivered into the blood stream home to sites of injury. The mechanism of mesenchymal stem cell homing to sites of injury is poorly understood.
Irina A Potapova +2 more
doaj +1 more source
Prostaglandin E Positively Modulates Endothelial Progenitor Cell Homeostasis: An Advanced Treatment Modality for Autologous Cell Therapy [PDF]
Aims: The mobilization of endothelial progenitor cells (EPC) and their functioning in postnatal neovascularization are tightly regulated. To identify new modulators of EPC homeostasis, we screened biologically active prostaglandin E compounds for their ...
Hermann, Patrick C. +6 more
core +1 more source
Circulating endothelial cells demonstrate an attenuation of endothelial damage by minimizing the extracorporeal circulation [PDF]
Detachment of endothelial cells may represent serious injury of the endothelium after cardiopulmonary bypass. We investigated whether the extent of endothelial injury is related to the type of cardiopulmonary bypass system used (conventional or minimized) and determined circulating endothelial cells as well as von Willebrand factor and soluble ...
Skrabal, Christian A. +6 more
openaire +2 more sources
SDF1 Gene Variation Is Associated with Circulating SDF1 alpha Level and Endothelial Progenitor Cell Number-The Bruneck Study [PDF]
BACKGROUND: Stromal cell-derived factor-1 (SDF1) and its receptor CXC chemokine receptor 4 (CXCR4) play a critical role in progenitor cell homing, mobilization and differentiation.
Marjan Jahangiri +31 more
core +1 more source
Circulating Endothelial Cells in Vasculitis and Transplantation [PDF]
Damage to microvascular endothelial cells is the hallmark of small-vessel vasculitis. Based on the histology, however, an intriguing question has long been unanswered: Given that cells undergo detachment from the basement, what happens to these cells and can we detect them in peripheral blood? Moreover, it seemed reasonable to assume that the number of
openaire +2 more sources

