Results 41 to 50 of about 4,985,545 (281)

Caspases and p38 MAPK regulate endothelial cell adhesiveness for mesenchymal stem cells. [PDF]

PLoS ONE, 2013
Mesenchymal stem cells natively circulating or delivered into the blood stream home to sites of injury. The mechanism of mesenchymal stem cell homing to sites of injury is poorly understood.
Irina A Potapova, Ira S Cohen, Sergey V Doronin   +2 more
doaj   +1 more source

Circulating progenitor cell count for cardiovascular risk stratification: a pooled analysis [PDF]

, 2010
Background: Circulating progenitor cells (CPC) contribute to the homeostasis of the vessel wall, and a reduced CPC count predicts cardiovascular morbidity and mortality.
Zeiher Andreas M., ZEIHER AM, Saula de Kreutzenberg, Ozaki Takenori, MARUYAMA S, Schmidt-Lucke, Caroline, Andreas M. Zeiher, Takenori Ozaki, Schmidt-Lucke Caroline, Avogaro, Angelo, WERNER N., Meigs, James, Nikos Werner, Meigs James, SCHMIDT LUCKE C, VIGILI DE KREUTZENBERG, SAULA, Shoichi Maruyama, Werner, Nikos, Fadini, Gian Paolo, Nickenig, Georg, OZAKI T, Taguchi Akihiko, DIMMELER S, Caroline Schmidt-Lucke, Werner Nikos, Taguchi, Akihiko, Andreas M Zeiher, MEIGS J, NICKENIG G, Maruyama Shoichi, Angelo Avogaro, Ozaki, Takenori, Gian Paolo Fadini, Fadini Gian Paolo, TAGUCHI A, Dimmeler Stefanie, Stefanie Dimmeler, Dimmeler, Stefanie, De Kreutzenberg, Saula, Maruyama, Shoichi, Akihiko Taguchi, Zeiher, Andreas M., James Meigs, Nickenig Georg, Avogaro Angelo, Georg Nickenig, de Kreutzenberg Saula   +46 more
core   +2 more sources

In vitro Flow Adhesion Assay for Analyzing Shear-resistant Adhesion of Metastatic Cancer Cells to Endothelial Cells

Bio-Protocol, 2016
Hematogenous metastasis is a primary cause of mortality from metastatic cancer. The shear-resistant adhesion of circulating tumor cells to the vascular endothelial cell surface under blood flow is an essential step in cell extravasation and further ...
Shin-Ae Kang, Sandra Bajana, Takemi Tanaka   +2 more
doaj   +1 more source

SDF1 Gene Variation Is Associated with Circulating SDF1 alpha Level and Endothelial Progenitor Cell Number-The Bruneck Study [PDF]

, 2008
BACKGROUND: Stromal cell-derived factor-1 (SDF1) and its receptor CXC chemokine receptor 4 (CXCR4) play a critical role in progenitor cell homing, mobilization and differentiation.
Marjan Jahangiri, Kiechl, Stefan, Mayr, A, Willeit, J, Qingzhong Xiao, Friedrich Oberhollenzer, Xu Qingbo, Jahangiri, M, Ye Shu, Oberhollenzer Friedrich, Jahangiri, Marjan, Willeit Johann, Mayr, Agnes, Oberhollenzer, F, Mayr Agnes, Willeit, Johann, Ye, Shu, Xiao, Q, Ye, S, Kiechl, S, Kiechl Stefan, Xu, Q, Jahangiri Marjan, Stefan Kiechl, Qingbo Xu, Xiao Qingzhong, Johann Willeit, Oberhollenzer, Friedrich, Xu, Qingbo, Shu Ye, Agnes Mayr, Xiao, Qingzhong   +31 more
core   +2 more sources

Circulating endothelial cells demonstrate an attenuation of endothelial damage by minimizing the extracorporeal circulation [PDF]

The Journal of Thoracic and Cardiovascular Surgery, 2006
Detachment of endothelial cells may represent serious injury of the endothelium after cardiopulmonary bypass. We investigated whether the extent of endothelial injury is related to the type of cardiopulmonary bypass system used (conventional or minimized) and determined circulating endothelial cells as well as von Willebrand factor and soluble ...
Skrabal, Christian A., Choi, Yeong H., Kaminski, Alexander, Steiner, Michael, Kundt, Guenther, Steinhoff, Gustav, Liebold, Andreas   +6 more
openaire   +2 more sources

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Maximal Exercise Improves the Levels of Endothelial Progenitor Cells in Heart Failure Patients

Current Issues in Molecular Biology, 2023
The impact of exercise on the levels of endothelial progenitor cells (EPCs), a marker of endothelial repair and angiogenesis, and circulating endothelial cells (CECs), an indicator of endothelial damage, in heart failure patients is largely unknown. This
Suiane Cavalcante, Sofia Viamonte, Rui S. Cadilha, Ilda P. Ribeiro, Ana Cristina Gonçalves, João Sousa-Venâncio, Marisol Gouveia, Manuel Teixeira, Mário Santos, José Oliveira, Fernando Ribeiro   +10 more
doaj   +1 more source

Circulating Endothelial Cells in Vasculitis and Transplantation [PDF]

Pathophysiology of Haemostasis and Thrombosis, 2003
Damage to microvascular endothelial cells is the hallmark of small-vessel vasculitis. Based on the histology, however, an intriguing question has long been unanswered: Given that cells undergo detachment from the basement, what happens to these cells and can we detect them in peripheral blood? Moreover, it seemed reasonable to assume that the number of
openaire   +2 more sources

Decoding the dynamic extracellular matrix in cancer—3D models and bioscaffolds rewire the rules of tumor progression

FEBS Letters, EarlyView.
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani, Konstantinos Spanopoulos, Zoi Piperigkou, Nikos K. Karamanos   +3 more
wiley   +1 more source

Relevance of monocytic features for neovascularization capacity of circulating endothelial progenitor cells [PDF]

, 2003
Background— Transplantation of ex vivo expanded circulating endothelial progenitor cells (EPCs) from peripheral blood mononuclear cells improves the neovascularization after critical ischemia. However, the origin of the endothelial progenitor lineage and
Dimmeler, S, Heeschen, C, Aicher, A, Urbich, C, Zeiher, AM, Dernbach, E   +5 more
core