Results 61 to 70 of about 4,985,545 (281)

Prostaglandin E Positively Modulates Endothelial Progenitor Cell Homeostasis: An Advanced Treatment Modality for Autologous Cell Therapy [PDF]

, 2009
Aims: The mobilization of endothelial progenitor cells (EPC) and their functioning in postnatal neovascularization are tightly regulated. To identify new modulators of EPC homeostasis, we screened biologically active prostaglandin E compounds for their ...
Hermann, Patrick C., Schwarz, Theresa M., Kopp, Reinhard, Huber, Stephan, Heeschen, Christopher, Herrler, Tanja, Leicht, Simon F.   +6 more
core   +1 more source

CXCR4pos circulating progenitor cells coexpressing monocytic and endothelial markers correlating with fibrotic clinical features are present in the peripheral blood of patients affected by systemic sclerosis

Haematologica, 2008
There is still controversy regarding the role of circulating endothelial and progenitor cells (CECs/CEPs) in the pathogenesis of systemic sclerosis (SSc).
Diana Campioni, Andrea Lo Monaco, Francesco Lanza, Sabrina Moretti, Luisa Ferrari, Maria Fotinidi, Renato La Corte, Antonio Cuneo, Francesco Trotta   +8 more
doaj   +1 more source

Circulating Endothelial Cells as Marker of Endothelial Damage in Male Hypogonadism [PDF]

Journal of Andrology, 2012
Abstract: Testosterone deficiency has become a frequently diagnosed condition in today's society affected by epidemic obesity, and is associated with cardiovascular risk. Recent studies have established the importance of altered vascular endothelium function in cardiovascular disease.
Milardi, Domenico, Grande, Giuseppe, Giampietro, Antonella, Vendittelli, Francesca, Palumbo, Sara, Tartaglione, Linda, Marana, Riccardo, Pontecorvi, Alfredo, De Marinis, Laura, Zuppi, Cecilia, Capoluongo, Ettore Domenico   +10 more
openaire   +3 more sources

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source

Shedding light on the elusive role of endothelial cells in cytomegalovirus dissemination. [PDF]

, 2011
Cytomegalovirus (CMV) is frequently transmitted by solid organ transplantation and is associated with graft failure. By forming the boundary between circulation and organ parenchyma, endothelial cells (EC) are suited for bidirectional virus spread from ...
Jauch, Karl-Walter, Sacher, Torsten, Lars Dölken, Aivars Kalnins, Matthias J Reddehase, Ulrich H Koszinowski, Koszinowski, Ulrich H., Zsolt Ruzsics, Podlech, Jürgen, Karl-Walter Jauch, Ruzsics, Zsolt, Andrassy, Joachim, Dölken, Lars, Joachim Andrassy, Matthias J. Reddehase, Jordan, Stefan, Ulrich H. Koszinowski, Reddehase, Matthias J., Stefan Jordan, Kalnins, Aivars, Torsten Sacher, Jürgen Podlech   +21 more
core   +2 more sources

Progenitor cell mobilisation and recruitment in pulmonary arteries in chronic obstructive pulmonary disease

Respiratory Research, 2019
Background Pulmonary vascular abnormalities are a characteristic feature of chronic obstructive pulmonary disease (COPD). Cigarette smoking is the most important risk factor for COPD.
Olga Tura-Ceide, Sandra Pizarro, Jéssica García-Lucio, Josep Ramírez, Laureano Molins, Isabel Blanco, Yolanda Torralba, Marta Sitges, Cristina Bonjoch, Victor I. Peinado, Joan Albert Barberà   +10 more
doaj   +1 more source

Pregnancy-Induced Hypertension is Accompanied by Decreased Number of Circulating Endothelial Cells and Circulating Endothelial Progenitor Cells [PDF]

Archivum Immunologiae et Therapiae Experimentalis, 2014
Maternal endothelial dysfunction is one of the main features of pregnancy-induced hypertension (PIH). It is generally accepted that circulating endothelial cells (CECs) and endothelial progenitor cells (EPCs) reflect the state of the endothelium, its injury and/or repair possibilities.
Heimrath, Jerzy, Paprocka, Maria, Andrzej Czekański, Ledwożyw, Agata, Kantor, Aneta, Duś, Danuta   +5 more
openaire   +3 more sources

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Beneficial influence of low-density lipoprotein cholesterol on the endothelium in relation to endothelial repair

Environmental Health and Preventive Medicine
Background: Low-density lipoprotein cholesterol (LDLc) is regarded as a risk factor for endothelial dysfunction. However, LDLc stimulates the proliferation of hematopoietic stem cells (CD34-positive cells), which contribute to endothelial repair ...
Yuji Shimizu, Shin-Ya Kawashiri, Hirotomo Yamanashi, Seiko Nakamichi, Naomi Hayashida, Yasuhiro Nagata, Takahiro Maeda   +6 more
doaj   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source