Results 71 to 80 of about 981,735 (367)

Nanopatterned acellular valve conduits drive the commitment of blood-derived multipotent cells [PDF]

, 2016
Considerable progress has been made in recent years toward elucidating the correlation among nanoscale topography, mechanical properties, and biological behavior of cardiac valve substitutes.
Aguiari, Paola, Barbon, Silvia, Bertalot, Thomas, Conconi, MARIA TERESA, DI LIDDO, Rosa, Gandaglia, Alessandro, Gerosa, Gino, Iop, Laura, Mandoli, Amit, Parnigotto, PIER PAOLO, Schrenk, Sandra, Tasso, Alessia   +11 more
core   +2 more sources

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Physalis minima Leaves Extract Induces Re-Endothelialization in Deoxycorticosterone Acetate-Salt-Induced Endothelial Dysfunction in Rats

Research Journal of Life Science, 2018
The administration of deoxy-corticosterone acetate (DOCA)-salt can induce oxidative stress leading to decrease the bioavailability of nitric oxide (NO), increase senescence of circulating endothelial progenitor cells (EPCs), thus contributing to ...
Dian Nugrahenny, Nur Permatasari, Mohammad Saifur Rohman   +2 more
doaj   +1 more source

Maximal Exercise Improves the Levels of Endothelial Progenitor Cells in Heart Failure Patients

Current Issues in Molecular Biology, 2023
The impact of exercise on the levels of endothelial progenitor cells (EPCs), a marker of endothelial repair and angiogenesis, and circulating endothelial cells (CECs), an indicator of endothelial damage, in heart failure patients is largely unknown. This
Suiane Cavalcante, Sofia Viamonte, Rui S. Cadilha, Ilda P. Ribeiro, Ana Cristina Gonçalves, João Sousa-Venâncio, Marisol Gouveia, Manuel Teixeira, Mário Santos, José Oliveira, Fernando Ribeiro   +10 more
doaj   +1 more source

Estrogen stimulates dimethylarginine dimethylaminohydrolase activity and the metabolism of asymmetric dimethylarginine. [PDF]

, 2003
Background— Experimental evidence suggests that estrogens stimulate the production of nitric oxide (NO) by vascular endothelial cells. This effect has been attributed to increased expression and enzymatic activity of both the constitutive and inducible ...
Cartwright, JE, Holden, DP, Nussey, SS, Whitley, GS   +3 more
core   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Endothelial CD276 (B7-H3) expression is increased in human malignancies and distinguishes between normal and tumour-derived circulating endothelial cells

British Journal of Cancer, 2014
Background:Mature circulating endothelial cells (CEC) are surrogate markers of endothelial damage. CEC measured in patients with advanced cancer are thought not only to derive from damaged normal vasculature (n-CEC), but also from damaged (t-CEC ...
J. Kraan, P. V. D. Broek, C. Verhoef, D. Grünhagen, W. Taal, J. Gratama, S. Sleijfer   +6 more
semanticscholar   +1 more source

RIPK4 function interferes with melanoma cell adhesion and metastasis

Molecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski, Sławomir Lasota, Ewelina Madej, Anna A. Brożyna, Małgorzata Szczygieł, Agnieszka Harazin‐Lechowska, Jan Czerbniak, Janusz Rys, Jaroslaw Czyz, Agnieszka Wolnicka‐Glubisz   +9 more
wiley   +1 more source

Innovative Flow Cytometry Allows Accurate Identification of Rare Circulating Cells Involved in Endothelial Dysfunction. [PDF]

PLoS ONE, 2016
INTRODUCTION:Although rare, circulating endothelial and progenitor cells could be considered as markers of endothelial damage and repair potential, possibly predicting the severity of cardiovascular manifestations.
Federica Boraldi, Angelica Bartolomeo, Sara De Biasi, Stefania Orlando, Sonia Costa, Andrea Cossarizza, Daniela Quaglino   +6 more
doaj   +1 more source

Circulating Endothelial Progenitor Cells Exhibit Diurnal Variation [PDF]

Arteriosclerosis, Thrombosis, and Vascular Biology, 2008
Endothelial progenitor cells (EPCs) are circulating bone marrow–derived mononuclear cells that have the potential to promote postnatal neovascularization and endothelial repair.1 Reduced numbers of EPCs have been demonstrated in patients with coronary artery disease (CAD) and those with cardiac risk factors including smoking, hyperlipidemia ...
Thomas HE, Redgrave R, Cunnington MS, Avery P, Keavney BD, Arthur HM   +5 more
openaire   +4 more sources