Results 141 to 150 of about 256,540 (247)

Marked Long‐Term Improvement in Lung Function in Melanoma Differentiation–Associated Protein 5 Antibody–Positive Dermatomyositis Patients: Experience of a Single‐Center Longitudinal Cohort in North America

Arthritis Care &Research, EarlyView.
Objective The objective of this study was to describe the longitudinal disease course and pulmonary outcomes of North American patients with melanoma differentiation–associated protein 5 (MDA5) antibody–associated dermatomyositis (DM). Methods Thirty patients with MDA5 antibody–associated DM were identified in a single‐center longitudinal cohort of 352
Jenice X. Cheah, Sangmee S. Bae, Tiffany De Leon, Yuna Lee, Rong Guo, David Elashoff, Jennifer Wang, Ani Shahbazian, Christina Charles‐Schoeman   +8 more
wiley   +1 more source

Table_2_Two-sample Mendelian randomization analysis of 91 circulating inflammatory protein levels and amyotrophic lateral sclerosis.XLS [PDF]

IntroductionAmyotrophic Lateral Sclerosis (ALS) is a neurodegenerative disease with poorly understood pathophysiology. Recent studies have highlighted systemic inflammation, especially the role of circulating inflammatory proteins, in ALS.MethodsThis ...
Jing Shen (308587), Chenxu Xiao (18260365), Xiaochu Gu (9113764), Yu Feng (445691)   +3 more
core   +1 more source

Building a Framework for Sexual and Reproductive Health Care in the Rheumatology Context: Content and Approaches

Arthritis Care &Research, EarlyView.
People with systemic autoimmune and rheumatic diseases (SARDs) are at higher risk than the general population of experiencing adverse pregnancy and perinatal outcomes such as preeclampsia, intrauterine growth restriction, and maternal and/or fetal death.
Mehret Birru Talabi, Sonya Borrero
wiley   +1 more source

Causal Relationships Between Circulating Inflammatory Proteins and Obstructive Sleep Apnea: A Bidirectional Mendelian Randomization Study

Nature and Science of Sleep
Zhengjie Chen,1,2,* Jinjie Zeng,3,* Xiang Pei,1,2 Jingjing Zhao,1,2 Fang Zhao,1,2 Guoxin Zhang,1,2 Kexin Liang,1,2 Jiarong Li,2 Xiaoyun Zhao1,2,4,5 1Clinical School of Thoracic, Tianjin Medical University, Tianjin, People’s Republic of China ...
Chen Z, Zeng J, Pei X, Zhao J, Zhao F, Zhang G, Liang K, Li J, Zhao X   +8 more
doaj  

Clinical, Histologic, and Serological Predictors of Renal Function Loss in Lupus Nephritis

Arthritis Care &Research, EarlyView.
Objective Kidney survival is the ultimate goal in lupus nephritis (LN) management, but long‐term predictors remain inadequately studied, requiring long‐term follow‐up. This study aimed to identify baseline and early longitudinal predictors of kidney survival in the Accelerating Medicines Partnership LN longitudinal cohort.
Shangzhu Zhang, Laurence Magder, Daniel Goldman, Judith A. James, Joel M. Guthridge, Carla Guthridge, Peter Izmirly, Jill P. Buyon, H. Michael Belmont, Richard A. Furie, Noa Schwartz, Chaim Putterman, Jennifer L. Barnas, Jennifer H. Anolik, Sarah French, Maria Dall'Era, Avi Z. Rosenberg, Jeffrey Hodgin, Dawit S. Demeke, the Accelerating Medicines Partnership Rheumatoid Arthritis and Systemic Lupus Erythematosus (RA/SLE) Network, Michelle Petri, Andrea Fava   +21 more
wiley   +1 more source

The role relationship played by immune cells and circulating inflammatory proteins in NAFLD

Abstract Objective The mechanisms by which immune cells and inflammatory factors influence Non-Alcoholic Fatty Liver Disease (NAFLD) remain unclear. This study employs Mendelian randomization (MR) to investigate the relationship between immune cells, inflammatory factors, and NAFLD, as well as the proportion of their mutual mediation effects ...
Zhenfei Chi, Yanyun Zhang, Xuesong Bai, Baoying Zhao, Zhe Zhang   +4 more
openaire   +1 more source

Rheumatoid Arthritis and Coronary Artery Calcium Progression: A Case Cohort Analysis From ELSA‐Brasil

Arthritis Care &Research, EarlyView.
Objective To investigate the association between rheumatoid arthritis (RA) and coronary artery calcium (CAC) prevalence, incidence, and progression over four years in adults without prior cardiovascular disease. Methods A case‐cohort study within the Brazilian Longitudinal Study of Adult Health (ELSA‐Brasil) included 585 participants (86 patients with ...
Patrícia Fonseca Estrada, Marcos Rafael N. Cavalcante, Itamar de Souza Santos, Márcio S. Bittencourt, Vandrize Meneghini, Paulo A. Lotufo, Alessandra C. Goulart, Isabela M. Bensenor   +7 more
wiley   +1 more source

Genetically predicted the causal association between circulating inflammatory proteins and sepsis

Abstract Background Sepsis is a severe complication originating from an imbalanced host response to infection. Based on previous studies, the protein profile shows crucial participation in sepsis pathology. Observational studies on the relationship of circulating inflammatory proteins with sepsis susceptibility often confront difficulties ...
Zhaoyi Jing, Qingyu Song, Xianghua Qi, Lei Wang   +3 more
openaire   +1 more source

Fusogenic RNA Nanomodules for Fusion‐Mediated and Multiplexed siRNA Delivery

Advanced Functional Materials, EarlyView.
A fusogenic lipid‐layered RNA nanomodules (L‐CRAMs) enable high‐capacity and long‐lasting siRNA delivery through membrane fusion. These nanomodules carry exceptionally large siRNA payloads, avoid conventional endosomal uptake, and release multiple functional siRNAs through Dicer‐mediated processing.
Sunghyun Moon, Iksoo Jang, Taehyeon Kim, Nayoung Yoon, Kyuha Yum, Jong Bum Lee   +5 more
wiley   +1 more source

Causal Effects of Circulating Inflammatory Proteins on Postmenopausal Atrophic Vaginitis in European Populations: A Mendelian Randomization Study with Transcriptomic Validation

International Journal of Women's Health
Xianyang Hu,1,2,* Shuai Ruan,3,* Tianyu Zhong,1,4 Fuju Zhao11Clinical Laboratory, Huadong Hospital, Fudan University, Shanghai, People’s Republic of China; 2Laboratory for Reproductive Immunology, Shanghai Key Laboratory of Female ...
Hu X, Ruan S, Zhong T, Zhao F
doaj