Results 21 to 30 of about 115,123 (247)

Insulin-like growth factor-1 is a negative modulator of glucagon secretion [PDF]

open access: yes, 2017
Glucagon secretion involves a combination of paracrine, autocrine, hormonal, and autonomic neural mechanisms. Type 2 diabetes often presents impaired glucagon suppression by insulin and glucose.
Andreozzi, F   +6 more
core   +1 more source

Circulating HFMD-associated coxsackievirus A16 is genetically and phenotypically distinct from the prototype CV-A16. [PDF]

open access: yesPLoS ONE, 2014
Human enteroviruses (HEV) have been linked to hand, foot, and mouth disease (HFMD) in the Pacific and Southeast Asia for decades. Many cases of HFMD have been attributed to coxsackievirus A16 (CV-A16, CA16), based on only partial viral genome ...
Wei Wei   +12 more
doaj   +1 more source

Inter- and intracontinental migrations and local differentiation have shaped the contemporary epidemiological landscape of canine parvovirus in South America [PDF]

open access: yes, 2018
Canine parvovirus (CPV) is a fast-evolving single-stranded DNA virus that causes one of the most significant infectious diseasesof dogs. Although the virus dispersed over long distances in the past, current populations are considered to be ...
Aldaz, Jaime   +11 more
core   +1 more source

THE PREVALENCE OF HIV RECOMBINANT FORMS IN RUSSIA AND COUNTRIES OF THE CIS: SYSTEMATIC REVIEW AND METAANALYSIS

open access: yesИнфекция и иммунитет, 2018
This review was to aimed to access the prevalence of HIV recombinant forms in Russia and countries of the CIS, which have  close social and economic ties. We conducted a search in Russian  Science Citation Index and PubMed for a depth of 8 years.
O. A. Pasechnik, A. I. Blokh
doaj   +1 more source

Molecular Epidemiology of HIV-1 in African Countries: A Comprehensive Overview

open access: yesPathogens, 2020
The human immunodeficiency virus type 1 (HIV-1) originated in non-human primates in West-central Africa and continues to be a major global public health issue, having claimed almost 33 million lives so far.
Marta Giovanetti   +3 more
doaj   +1 more source

Neuregulin-1 attenuates experimental cerebral malaria (ECM) pathogenesis by regulating ErbB4/AKT/STAT3 signaling. [PDF]

open access: yes, 2018
BACKGROUND:Human cerebral malaria (HCM) is a severe form of malaria characterized by sequestration of infected erythrocytes (IRBCs) in brain microvessels, increased levels of circulating free heme and pro-inflammatory cytokines and chemokines, brain ...
Cespedes, Juan Carlos   +5 more
core   +1 more source

Erythrocytes as Carriers of Therapeutic Enzymes. [PDF]

open access: yes, 2020
Therapeutic enzymes are administered for the treatment of a wide variety of diseases. They exert their effects through binding with a high affinity and specificity to disease-causing substrates to catalyze their conversion to a non-noxious product, to ...
Bax, BE
core   +1 more source

HIV-1 subtype diversity and transmission strain source among men who have sex with men in Guangxi, China

open access: yesScientific Reports, 2021
With the rapid increase in HIV prevalence of men who have sex with men (MSM) in recent years and common human migration and travelling across different provinces in China, MSM are now finding it easier to meet each other, which might contribute to local ...
Yi Chen   +13 more
doaj   +1 more source

Comprehensive Characterization of the Transmitted/Founder env Genes From a Single MSM Cohort in China [PDF]

open access: yes, 2015
Background: The men having sex with men (MSM) population has become one of the major risk groups for HIV-1 infection in China. However, the epidemiological patterns, function of the env genes, and autologous and heterologous neutralization activity in ...
Cai, F   +13 more
core   +1 more source

Higher transactivation activity associated with LTR and Tat elements from HIV-1 BF intersubtype recombinant variants

open access: yesRetrovirology, 2006
Background HIV-1 is characterized by its rapid genetic evolution and high diversity as a consequence of its error-prone reverse transcriptase and genetic recombination.
Gómez-Carrillo Manuel   +5 more
doaj   +1 more source

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