Results 111 to 120 of about 2,068,901 (353)

Current Methods of Circulating Tumor Cell Detection

The Korean Journal of Helicobacter and Upper Gastrointestinal Research, 2018
Liquid biopsy, the analysis of circulating biomarkers from peripheral blood, such as circulating tumor cells (CTCs) and circulating tumor DNA, and exosomes, offers a less invasive, new source of cancer-derived materials that may reflect the status of the
Minji Lim, Yoon-Kyoung Cho
doaj   +1 more source

Distinct immune signatures in directly treated and distant tumors result from TLR adjuvants and focal ablation. [PDF]

, 2018
Both adjuvants and focal ablation can alter the local innate immune system and trigger a highly effective systemic response. Our goal is to determine the impact of these treatments on directly treated and distant disease and the mechanisms for the ...
Borowsky, Alexander D, Chavez, Michael, Davis, Ryan R, Ferrara, Katherine W, Fite, Brett Z, Hubbard, Neil E, Ilovitsh, Asaf, Ingham, Elizabeth S, Mahakian, Lisa M, Monjazeb, Arta M, Murphy, William J, Silvestrini, Matthew T, Tam, Sarah M, Tepper, Clifford G   +13 more
core   +1 more source

Supplementary Figure 6 from Fes Tyrosine Kinase Expression in the Tumor Niche Correlates with Enhanced Tumor Growth, Angiogenesis, Circulating Tumor Cells, Metastasis, and Infiltrating Macrophages [PDF]

, 2023
Shengnan Zhang, Violeta Chiţu, E. Richard Stanley, Bruce E. Elliott, Peter A. Greer   +4 more
openalex   +1 more source

Plasma extrachromosomal circular DNA as a biomarker in EGFR‐targeted therapy of non‐small cell lung cancer

Molecular Oncology, EarlyView.
Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard, Sarmad Mehmood, Eva Boysen Fynboe Ebert, Peter Meldgaard, Anindya Dutta, Boe S. Sorensen   +5 more
wiley   +1 more source

Kras mutation correlating with circulating regulatory T cells predicts the prognosis of advanced pancreatic cancer patients

Cancer Medicine, 2020
Purpose Kras mutation and abnormal immune status are associated with pancreatic cancer development and progression. In this study, we evaluated the Kras mutation status in circulating tumor DNA and circulating T cell subsets in a cohort of advanced ...
He Cheng, Guopei Luo, Kaizhou Jin, Zhiyao Fan, Qiuyi Huang, Yitao Gong, Jin Xu, Xianjun Yu, Chen Liu   +8 more
doaj   +1 more source

Niche inheritance: a cooperative pathway to enhance cancer cell fitness though ecosystem engineering [PDF]

, 2014
Cancer cells can be described as an invasive species that is able to establish itself in a new environment. The concept of niche construction can be utilized to describe the process by which cancer cells terraform their environment, thereby engineering ...
Barar J, Elton CS, Faraji F, Fidler IJ, Folkman J, Gatenby RA, Healy M, Hutchinson GE, Odling‐Smee FJ, Odling‐Smee FJ, Paget S, Pienta KJ, Weiss L, Wey JS   +13 more
core   +2 more sources

Liquid biopsy and therapeutic response: Circulating tumor cell cultures for evaluation of anticancer treatment

Science Advances, 2016
A patient-derived CTC culture assay for anticancer drug evaluation to guide therapy for personalized treatment. The lack of a robust anticancer drug screening system to monitor patients during treatment delays realization of personalized treatment.
B. L. Khoo, G. Grenci, T. Jing, Ying Bena Lim, S. C. Lee, J. Thiery, Jongyoon Han, C. Lim   +7 more
semanticscholar   +1 more source

Glycosylated LGALS3BP is highly secreted by bladder cancer cells and represents a novel urinary disease biomarker

Molecular Oncology, EarlyView.
Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece, Giulio Lovato, Ilaria Cela, Arianna Mercatelli, Benedetta Ferro, Jussi Nikkola, Sara Pagotto, Tommaso Grottola, Vincenzo De Laurenzi, Rossella Cicchetti, Antonio Marchetti, Luigi Schips, Rossano Lattanzio, Stefano Iacobelli, Emily Capone, Peter Black, Mads Daugaard, Michele Marchioni, Gianluca Sala   +18 more
wiley   +1 more source

Circulating tumor cells and clusters as liquid biomarkers for the diagnosis and prognosis of neuroblastoma

BMC Cancer
Background The clinical significance of circulating tumor cell (CTC) clusters in highly metastatic tumors hasn’t yet been revealed. Here, we demonstrated the diagnostic and prognostic value of CTC clusters in neuroblastoma (NB) which is the most ...
Huanli Xu, Nianhua Cao, Wenyan Dai, Caiwei Sima, Meng Yi, Senmin Chen, Xiaowen Chen, Chao Liu, Uet Yu, Huiping Lang, Zhedie Zhou, Nanlin Yang, Chunjing Wang, Xianping Jiang, Yungen Gan, Jianyao Wang, Yuanxiang Wang, Nuaner Yao, Lidan Xiao, Qing Zhang, Junjie Sun, Zhou Lin, Gongwei Zhang, Jiayue Zhang, Hongtao Feng, Jianming Song, Sixi Liu, Zongbin Liu, Feiqiu Wen, Xiuli Yuan   +29 more
doaj   +1 more source

A potential role for Dkk-1 in the pathogenesis of osteosarcoma predicts novel diagnostic and treatment strategies. [PDF]

, 2007
Canonical Wnt signaling is an osteo-inductive signal that promotes bone repair through acceleration of osteogenic differentiation by progenitors. Dkk-1 is a secreted inhibitor of canonical Wnt signaling and thus inhibits osteogenesis.
Angela Smolarz, Carl Gregory, Darwin Prockop, Edwin Horwitz, Jacob Reiser, Najat Daw, Narae Lee, Odile David, Robert Kutner, Scott Olson   +9 more
core   +3 more sources