Results 121 to 130 of about 2,068,901 (353)

Circulating tumor cell isolation for cancer diagnosis and prognosis

EBioMedicine, 2022
Zicheng Deng, Shengming Wu, Yilong Wang, Donglu Shi   +3 more
semanticscholar   +1 more source

The Landscape of Actionable Genomic Alterations in Cell-Free Circulating Tumor DNA from 21,807 Advanced Cancer Patients

Clinical Cancer Research, 2017
Purpose: Cell-free DNA (cfDNA) sequencing provides a noninvasive method for obtaining actionable genomic information to guide personalized cancer treatment, but the presence of multiple alterations in circulation related to treatment and tumor ...
Oliver A. Zill, K. Banks, Stephen R. Fairclough, S. Mortimer, James V. Vowles, R. Mokhtari, D. Gandara, P. Mack, J. Odegaard, R. Nagy, A. Baca, H. Eltoukhy, Darya I. Chudova, R. Lanman, Amirali Talasaz   +14 more
semanticscholar   +1 more source

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

Molecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He, Chiara Testini, Neda Hekmati, Altea Bonello, Aglaia Schiza, Emmanuel Nwadozi, Mia Phillipson, Carina Strell, Michael Welsh   +8 more
wiley   +1 more source

Circulating tumor cell-blood cell crosstalk: Biology and clinical relevance.

Cell Reports, 2022
Thais Pereira-Veiga, Svenja Schneegans, K. Pantel, H. Wikman   +3 more
semanticscholar   +1 more source

Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA

Molecular Oncology, EarlyView.
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson, Anders Lade Nielsen, Boe Sandahl Sorensen   +2 more
wiley   +1 more source

Current status of liquid biopsies for the detection and management of prostate cancer

Cancer Management and Research, 2019
Yi-Tsung Lu, Kevin Delijani, Andrew Mecum, Amir GoldkornDivision of Medical Oncology, Department of Medicine, Keck School of Medicine and Translational and Clinical Science Program, USC Norris Comprehensive Cancer Center, University of Southern ...
Lu YT, Delijani K, Mecum A, Goldkorn A
doaj  

Detection of circulating tumor cells by cell block technique in malignant tumors

Journal of Cytology
Introduction: Cancer is a leading cause of death worldwide and is a major cause of morbidity. To deal with this magnitude of cancers and their diagnostic and prognostics, a multitude of prognostic biomarkers for various cancers have been explored over ...
Jahnvi Vijay, B Deepak Kumar, V Srinivasa Murthy   +2 more
doaj   +1 more source

Single-cell analyses of circulating tumor cells

Cancer Biology & Medicine, 2015
Circulating tumor cells (CTCs) are a population of tumor cells mediating metastasis, which results in most of the cancer related deaths. The number of CTCs in the peripheral blood of patients is rare, and many platforms have been launched for detection ...
Xi-Xi Chen, Fan Bai
doaj   +1 more source

Kinetics of Circulating Plasma Cell-Free DNA in Paediatric Classical Hodgkin Lymphoma [PDF]

, 2016
Levels of plasma cell-free DNA (cfDNA) of a large series of children with classical Hodgkin lymphoma (cHL) were evaluated and analyzed at diagnosis and during chemotherapy treatment in relation with clinical characteristics.
Basso, Giuseppe, Buffardi, Salvatore, Burnelli, Roberta, Carraro, Elisa, Elia, Caterina, Farruggia, Piero, Mascarin, Maurizio, Mussolin, Lara, Pillon, Marta, Primerano, Simona, Sala, Alessandra, Vinti, Luciana   +11 more
core   +2 more sources

Whole-exome sequencing of cell-free DNA and circulating tumor cells in multiple myeloma

Nature Communications, 2018
Liquid biopsies including circulating tumor cells (CTCs) and cell-free DNA (cfDNA) have enabled minimally invasive characterization of many cancers, but are rarely analyzed together.
S. Manier, S. Manier, S. Manier, Joel Park, Joel Park, M. Capelletti, M. Bustoros, S. Freeman, Gavin Ha, J. Rhoades, Chia-Jen Liu, D. Huynh, S. Reed, G. Gydush, K. Salem, D. Rotem, C. Freymond, A. Yosef, A. Perilla-Glen, L. Garderet, E. V. Allen, E. V. Allen, Shaji Kumar, J. C. Love, G. Getz, V. Adalsteinsson, I. M. Ghobrial, I. M. Ghobrial, I. M. Ghobrial   +28 more
semanticscholar   +1 more source