Results 21 to 30 of about 2,068,901 (353)

Circulating Tumor Cell Clusters: United We Stand Divided We Fall

International Journal of Molecular Sciences, 2020
The presence of circulating tumor cells (CTCs) and CTC clusters, also known as tumor microemboli, in biological fluids has long been described. Intensive research on single CTCs has made a significant contribution in understanding tumor invasion ...
S. Amintas, A. Bedel, F. Moreau-Gaudry, J. Boutin, L. Buscail, J. Merlio, V. Vendrely, S. Dabernat, E. Buscail   +8 more
semanticscholar   +1 more source

Circulating circRNA: a social butterfly in tumors

Frontiers in Oncology, 2023
Circular RNAs (circRNAs) are a class of single-stranded non-coding RNAs that form circular structures through irregular splicing or post-splicing events.
Shuo Miao, Shuo Miao, Qingsong Zhang
doaj   +1 more source

Rapid, ultra low coverage copy number profiling of cell-free DNA as a precision oncology screening strategy. [PDF]

, 2017
Current cell-free DNA (cfDNA) next generation sequencing (NGS) precision oncology workflows are typically limited to targeted and/or disease-specific applications.
Alva, Ajjai S, Brockman, Scott, Chinnaiyan, Arul M, Chugh, Rashmi, Feng, Felix Y, Grasso, Catherine S, Gursky, Amy, Haakenson, Christine, Henderson, James, Herman, Kirk, Hovelson, Daniel H, Husain, Hatim, Hussain, Maha H, Kamberov, Emmanuel, Kandarpa, Malathi, Kang, Qing, Krauss, John C, Langmore, John, Liu, Chia-Jen, Lonigro, Robert J, Mills, Ryan E, Morgan, Todd M, Quist, Michael J, Ramnath, Nithya, Robinson, Dan, Smith, David C, Talpaz, Moshe, Tesmer, Tim, Tewari, Muneesh, Tomlins, Scott A, Tuck, Missy, Wang, Yugang   +31 more
core   +1 more source

Circulating Tumor Cells and Fibronectin 1 in the Prognosis of Nasopharyngeal Carcinoma

Technology in Cancer Research & Treatment, 2020
Objective: Nasopharyngeal carcinoma is highly endemic in Southeast China. Circulating tumor cell is an important biomarker in the prognosis of variety kinds of cancers. Overexpression of fibronectin 1 was observed in variety kinds of malignancies and may
Ying Yu BM, Zhi-Xiu Lin BM, Hai-Wen Li MM, Hai-Qing Luo MD, Dong-Hong Yang MM, He-Chao Zhou MM, Dan-Xian Jiang MD, De-Chao Zhan MM, Liu Yang MM, Xiao-Ye Liang MM, Zhong-Hua Yu MM, Zi-Hong Chen BM   +11 more
doaj   +1 more source

Liquid-based biomarkers in breast cancer: looking beyond the blood

Journal of Translational Medicine, 2023
In recent decades, using circulating tumor cell (CTC), circulating tumor DNA (ctDNA), circulating tumor RNA (ctRNA), exosomes and etc. as liquid biomarkers has received enormous attention in various tumors, including breast cancer (BC).
You Shuai, Zhonghua Ma, Jie Ju, Tong Wei, Songlin Gao, Yikun Kang, Zixuan Yang, Xue Wang, Jian Yue, Peng Yuan   +9 more
doaj   +1 more source

The Role of Proteoglycans in Cancer Metastasis and Circulating Tumor Cell Analysis

Frontiers in Cell and Developmental Biology, 2020
Circulating tumor cells (CTCs) are accessible by liquid biopsies via an easy blood draw. They represent not only the primary tumor site, but also potential metastatic lesions, and could thus be an attractive supplement for cancer diagnostics.
Theresa D. Ahrens, S. Bang-Christensen, Amalie M Jørgensen, Caroline Løppke, Charlotte Spliid, Nicolai T. Sand, T. M. Clausen, A. Salanti, Mette Ø Agerbæk   +8 more
semanticscholar   +1 more source

Plasma next generation sequencing and droplet digital PCR‐based detection of epidermal growth factor receptor (EGFR) mutations in patients with advanced lung cancer treated with subsequent‐line osimertinib

Thoracic Cancer, 2019
Background Gene mutation analysis from plasma circulating tumor DNA (ctDNA) can provide timely information regarding the mechanism of resistance that could translate to personalised treatment.
Pei N. Ding, Therese Becker, Victoria Bray, Wei Chua, Yafeng Ma, Bo Xu, David Lynch, Paul de Souza, Tara Roberts   +8 more
doaj   +1 more source

Prognostic and predictive value of circulating tumor cells and CXCR4 expression as biomarkers for a CXCR4 peptide antagonist in combination with carboplatin-etoposide in small cell lung cancer: exploratory analysis of a phase II study. [PDF]

, 2017
Background Circulating tumor cells (CTCs) and chemokine (C-X-C motif) receptor 4 (CXCR4) expression in CTCs and tumor tissue were evaluated as prognostic or predictive markers of CXCR4 peptide antagonist LY2510924 plus carboplatin-etoposide (CE) versus ...
Baeten, Kurt, Connelly, Mark C, D'Haese, David, Flynt, Amy, Gross, Steve, McCleod, Michael, Morano, Carrie, Peek, Victoria L, Polzer, John, Raddad, Eyas, Repollet, Madeline, Roberson, Stephanie, Salgia, Ravi, Sanders, Renouard, Spigel, David R, Stille, John R, Um, Suzane L, Weaver, R Waide, Wijayawardana, Sameera R, Yan, S Betty   +19 more
core   +1 more source

Circulating Tumor Cell Composition in Renal Cell Carcinoma. [PDF]

PLoS ONE, 2016
PURPOSE:Due to their minimal-invasive yet potentially current character circulating tumor cells (CTC) might be useful as a "liquid biopsy" in solid tumors. However, successful application in metastatic renal cell carcinoma (mRCC) has been very limited so
Ivonne Nel, Thomas C Gauler, Kira Bublitz, Lazaros Lazaridis, André Goergens, Bernd Giebel, Martin Schuler, Andreas-Claudius Hoffmann   +7 more
doaj   +1 more source

The Potential for Circulating Tumor Cells in Pancreatic Cancer Management. [PDF]

, 2017
Pancreatic cancer is one the most lethal malignancies. Only a small proportion of patients with this disease benefit from surgery. Chemotherapy provides only a transient benefit.
Michael Pimienta, Michael Pimienta, Mouad Edderkaoui, Ruoxiang Wang, Stephen Pandol   +4 more
core   +2 more sources