Results 41 to 50 of about 6,088,596 (303)
Detection of Circulating Tumor Cells [PDF]
The increasing number of treatment options for patients with metastatic carcinomas has created an accompanying need for methods to determine if the tumor will be responsive to the intended therapy and to monitor its effectiveness. Ideally, these methods would be noninvasive and provide quantitative real-time analysis of tumor activity in a variety of ...
Sanne de Wit +2 more
openaire +3 more sources
Cyclophosphamide chemotherapy sensitizes tumor cells to TRAIL-dependent CD8 T cell-mediated immune attack resulting in suppression of tumor growth [PDF]
Background: Anti-cancer chemotherapy can be simultaneously lymphodepleting and immunostimulatory. Pre-clinical models clearly demonstrate that chemotherapy can synergize with immunotherapy, raising the question how the immune system can be mobilized to ...
Amy Prosser +51 more
core +2 more sources
Algorithm to identify circulating tumor cell clusters using in vivo flow cytometer [PDF]
Recent studies in oncology have addressed the importance of detecting circulating tumor cell clusters because circulating tumor cell clusters might survive and metastasize more easily than single circulating tumor cells.
Kai Pang +5 more
doaj +1 more source
The biology of circulating tumor cells [PDF]
Metastasis is a biologically complex process consisting of numerous stochastic events which may tremendously differ across various cancer types. Circulating tumor cells (CTCs) are cells that are shed from primary tumors and metastatic deposits into the blood stream.
K Pantel, M R Speicher
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While patients with resectable pancreatic ductal adenocarcinoma (PDAC) show improved survival compared to their non-resectable counterparts, survival remains low owing to occult metastatic disease and treatment resistance.
Pablo J. Dopico +7 more
doaj +1 more source
Circulating Tumor Cells and PET [PDF]
Understanding the distinct molecular features of solid tumors provides the opportunity to develop more targeted and effective therapies. The evaluation and monitoring of these therapies require sophisticated laboratory and imaging technologies to detect potential benefit not necessarily translating into significant changes in tumor size.
Jian Q, Yu, Massimo, Cristofanilli
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Specific antigen of tumor cell transformed by DNA extracted from SV-40 virus [PDF]
In the immunofluorescent study it has been revealed that rabbit sera immunized with transformed cells induced by SV-40 DNA, produce circulating antibody capable of re:lcting with intranuclear antigens synthesized by SV-40 complyte virus transforming ...
Okada, Shigeru +5 more
core +1 more source
Circulating cell-free DNA and circulating tumor cells, the “liquid biopsies” in ovarian cancer
Limited understanding of ovarian cancer (OC) genome portrait has hindered the therapeutic advances. The serial monitoring of tumor genotypes is becoming increasingly attainable with circulating cell-free DNA (cf-DNA) and circulating tumor cells (CTCs ...
Xianliang Cheng +3 more
doaj +1 more source
Tumor-induced myeloid cell plasticity toward lymphatic endothelium [PDF]
Tumor-associated lymphangiogenesis contributes to tumor progression by regulating interstitial fluid pressure, transporting immune cells to the tumor site and providing a route for metastatic dissemination.
Baeriswyl, Vanessa
core +1 more source
Circulating Tumor Cell and Cell-free Circulating Tumor DNA in Lung Cancer [PDF]
Circulating tumor cells (CTCs) are tumor cells that are separated from the primary site or metastatic lesion and disseminate in blood circulation. CTCs are considered to be part of the long process of cancer metastasis. As a 'liquid biopsy', CTC molecular examination and investigation of single cancer cells create an important opportunity for providing
Nurwidya, Fariz +6 more
openaire +2 more sources

