Results 21 to 30 of about 6,088,596 (303)

Gene expression in circulating tumor cells reveals a dynamic role of EMT and PD-L1 during osimertinib treatment in NSCLC patients

open access: yesScientific Reports, 2021
Liquid biopsy is a tool to unveil resistance mechanisms in NSCLC. We studied changes in gene expression in CTC-enriched fractions of EGFR-mutant NSCLC patients under osimertinib.
Aliki Ntzifa   +5 more
doaj   +1 more source

The Role of Liquid Biopsy Analytes in Diagnosis, Treatment and Prognosis of Colorectal Cancer

open access: yesFrontiers in Endocrinology, 2022
Colorectal cancer (CRC) is one of the most common malignant tumors of the digestive tract worldwide and is a serious threat to human life and health. CRC occurs and develops in a multi-step, multi-stage, and multi-gene process, in which abnormal gene ...
JinHua He   +8 more
doaj   +1 more source

Circulating tumor cells in genitourinary tumors [PDF]

open access: yesTherapeutic Advances in Urology, 2017
Management of advanced urogenital malignancies has profoundly changed in recent years due to the development of novel targeted drugs that have significantly improved patient’s clinical outcomes. This process has been made possible mainly thanks to better knowledge of tumor genetic alterations and molecular altered pathways.
Massari, Francesco   +8 more
openaire   +3 more sources

Enrichment of Circulating Tumor Cells of Lung Cancer and Correlation With Serum Leukomonocyte and Tumor Biomarkers: A Retrospective Study

open access: yesTechnology in Cancer Research & Treatment, 2023
Study design Circulating tumor cells is important in the clinical diagnosis of cancer and there are a number of circulating tumor cell detection systems associated with different isolation strategies being validated.
Zhou-Fang Mei MD   +7 more
doaj   +1 more source

The Value of Circulating Tumor Cells in the Prognosis and Treatment of Pancreatic Cancer

open access: yesFrontiers in Oncology, 2022
In the past few decades, tumor diagnosis and treatment theory have developed in a variety of directions. The number of people dying from pancreatic cancer increases while the mortality rate of other common tumors decreases.
Kai Luo   +5 more
doaj   +1 more source

The Value of Circulating Tumor Cells and Tumor Markers Detection in Lung Cancer Diagnosis

open access: yesTechnology in Cancer Research & Treatment, 2023
Objective Circulating tumor cells are complete tumor cells with multi-scale analysis values that present a high potential for lung cancer diagnosis. To enhance the accuracy of lung cancer diagnosis, we detected circulating tumor cells by the innovated ...
Sumin Guo MD   +10 more
doaj   +1 more source

SnapShot: Circulating Tumor Cells [PDF]

open access: yesCell, 2017
Circulating tumor cells in the blood of patients are both signal flares for the existence of a tumor and harbingers of metastasis. With recent technological developments, these cells can be isolated and analyzed to provide insights into the biology of cancer spread and response to therapy and to offer new avenues for blood biomarker development.
Caroline, Dive, Ged, Brady
openaire   +3 more sources

Circulating tumor cell technologies [PDF]

open access: yesMolecular Oncology, 2016
Circulating tumor cells, a component of the “liquid biopsy”, hold great potential to transform the current landscape of cancer therapy. A key challenge to unlocking the clinical utility of CTCs lies in the ability to detect and isolate these rare cells using methods amenable to downstream characterization and other applications. In this review, we will
Meghaan M, Ferreira   +2 more
openaire   +2 more sources

Detection of Tumor Cell-Specific mRNA in the Peripheral Blood of Patients with Breast Cancer-Evaluation of Several Markers with Real-Time Reverse Transcription-PCR [PDF]

open access: yes, 2013
It is widely known that cells from epithelial tumors, e. g., breast cancer, detach from their primary tissue and enter blood circulation. We show that the presence of circulating tumor cells (CTCs) in samples of patients with primary and metastatic ...
Simone Hofmann   +20 more
core   +1 more source

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