Circulating tumor cell technologies [PDF]
Molecular Oncology, 2016 Circulating tumor cells, a component of the “liquid biopsy”, hold great potential to transform the current landscape of cancer therapy. A key challenge to unlocking the clinical utility of CTCs lies in the ability to detect and isolate these rare cells using methods amenable to downstream characterization and other applications. In this review, we will
Meghaan M, Ferreira +2 more
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Specific antigen of tumor cell transformed by DNA extracted from SV-40 virus [PDF]
, 1967 In the immunofluorescent study it has been revealed that rabbit sera immunized with transformed cells induced by SV-40 DNA, produce circulating antibody capable of re:lcting with intranuclear antigens synthesized by SV-40 complyte virus transforming ...
Okada, Shigeru +5 more
core +1 more source
Isolation of circulating tumor cells
iScience, 2022 Circulating tumor cells (CTCs) enter the vasculature from solid tumors and disseminate widely to initiate metastases. Mining the metastatic-enriched molecular signatures of CTCs before, during, and after treatment holds unique potential in personalized oncology.
Jon F. Edd +6 more
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Zwitterionic microgel preservation platform for circulating tumor cells in whole blood specimen
Nature Communications, 2023 The immediate processing of whole blood specimen is required in circulating tumor cell-based liquid biopsy. Reliable blood specimen stabilization towards preserving circulating tumor cells can enable more extensive geographic sharing for precise rare ...
Yiming Ma +7 more
doaj +1 more source
Detection of Tumor Cell-Specific mRNA in the Peripheral Blood of Patients with Breast Cancer-Evaluation of Several Markers with Real-Time Reverse Transcription-PCR [PDF]
, 2013 It is widely known that cells from epithelial tumors, e. g., breast cancer, detach from their primary tissue and enter blood circulation. We show that the presence of circulating tumor cells (CTCs) in samples of patients with primary and metastatic ...
Simone Hofmann +20 more
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Current Status of Circulating Tumor Cells in Head and Neck Squamous Cell Carcinoma: A Review
, 2023 Objective Circulating tumor cells (CTCs) are found in the blood of patients with cancer, including head and neck squamous cell carcinomas (HNSCCs). The aim is to review the most up-to-date status of CTCs for applications in patients with HNSCC.
Gopalan, Vinod +9 more
core +1 more source
Using single-cell sequencing technology to detect circulating tumor cells in solid tumors
Molecular Cancer, 2021 Circulating tumor cells are tumor cells with high vitality and high metastatic potential that invade and shed into the peripheral blood from primary solid tumors or metastatic foci.
Jiasheng Xu +5 more
doaj +1 more source
Circulating circRNA: a social butterfly in tumors
Frontiers in Oncology, 2023 Circular RNAs (circRNAs) are a class of single-stranded non-coding RNAs that form circular structures through irregular splicing or post-splicing events.
Shuo Miao, Shuo Miao, Qingsong Zhang
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Circulating Tumor Cells and Fibronectin 1 in the Prognosis of Nasopharyngeal Carcinoma
Technology in Cancer Research & Treatment, 2020 Objective: Nasopharyngeal carcinoma is highly endemic in Southeast China. Circulating tumor cell is an important biomarker in the prognosis of variety kinds of cancers. Overexpression of fibronectin 1 was observed in variety kinds of malignancies and may
Ying Yu BM +11 more
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Liquid-based biomarkers in breast cancer: looking beyond the blood
Journal of Translational Medicine, 2023 In recent decades, using circulating tumor cell (CTC), circulating tumor DNA (ctDNA), circulating tumor RNA (ctRNA), exosomes and etc. as liquid biomarkers has received enormous attention in various tumors, including breast cancer (BC).
You Shuai +9 more
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