Deterministic Separation of Cancer Cells from Blood at 10 mL/min [PDF]
, 2012 Circulating tumor cells (CTCs) and circulating clusters of cancer and stromal cells have been identified in the blood of patients with malignant cancer and can be used as a diagnostic for disease severity, assess the efficacy of different treatment ...
Amy Wu +5 more
core +3 more sources
Frontiers in Oncology, 2018 The isolation of clusters of circulating tumor cells (CTCs) from cancer patients has recently challenged the accepted view that the initiation of secondary tumors during metastasis involves the dissemination of individual cancer cells.
Alexander N. May +2 more
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Circulating Tumor Cells in Cutaneous Melanoma [PDF]
Journal of Investigative Dermatology, 2011 n ...
De Giorgi V. +8 more
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Circulating tumor cell profiling for precision oncology
Molecular Oncology, 2021 Analysis of circulating tumor cells (CTCs) collected from patient's blood offers a broad range of opportunities in the field of precision oncology. With new advances in profiling technology, it is now possible to demonstrate an association between the ...
Mahmoud Labib, Shana O. Kelley
doaj +1 more source
Liquid Biopsy in Rare Cancers: Lessons from Hemangiopericytoma [PDF]
, 2018 Hemangiopericytoma (HPT) is a rare mesenchymal tumor of fibroblastic type and for its rarity is poorly studied. The most common sites of metastatic disease in patients with intracranial HPT are the bone, liver, and lung, suggestive for an hematogenous ...
Carpino, Guido +9 more
core +3 more sources
A pilot study evaluating concordance between blood-based and patient-matched tumor molecular testing within pancreatic cancer patients participating in the Know Your Tumor (KYT) initiative [PDF]
, 2016 Recent improvements in next-generation sequencing (NGS) technology have enabled detection of biomarkers in cell-free DNA in blood and may ultimately replace invasive tissue biopsies.
Aberra, Metasebia +15 more
core +2 more sources
Circulating Tumor Cells, Enumeration and Beyond [PDF]
Cancers, 2010 The detection and enumeration of circulating tumor cells (CTCs) has shown significant clinical utility with respect to prognosis in breast, colorectal and prostate cancers. Emerging studies show that CTCs can provide pharmacodynamic information to aid therapy decision making.
Hou, Jian Mei +6 more
openaire +3 more sources
microRNA. Diagnostic Perspective [PDF]
, 2015 Biomarkers are biological measures of a biological state. An ideal marker should be safe and easy to measure, cost efficient, modifiable with treatment, and consistent across gender and ethnic groups. To date, none of the available biomarkers satisfy all
FARUQ, MD OMAR, VECCHIONE, ANDREA
core +2 more sources
Limited utility of qPCR-based detection of tumor-specific circulating mRNAs in whole blood from clear cell renal cell carcinoma patients [PDF]
, 2020 BACKGROUND: RNA sequencing data is providing abundant information about the levels of dysregulation of genes in various tumors. These data, as well as data based on older microarray technologies have enabled the identification of many genes which are ...
Busch, Jonas +6 more
core +2 more sources
Role of circulating tumor DNA and circulating tumor cells in breast cancer: History and updates
SAGE Open Medicine, 2022 Circulating tumor DNA, cell-free DNA, and circulating tumor cells have been at the epitome of recent research in breast cancer. These forms of liquid biopsies have been used in monitoring disease progression, estimating the risk of relapse, and response ...
Julien Chedid +5 more
doaj +1 more source