Results 141 to 150 of about 6,850,236 (255)

Role of circulating tumor cell clusters in patients with metastatic hormone-sensitive prostate cancer receiving a gonadotropin-releasing hormone antagonist: A pilot study. [PDF]

Asian J Urol, 2023
Kohada Y, Kusumoto H, Kukimoto T, Mikami J, Ito J, Asano K, Yaegashi T, Nakagawara K, Teishima J, Kaiho Y, Hinata N, Nakamura Y, Sato M.   +12 more
europepmc   +1 more source

Mechanoactive Biomaterials for Cell–Matrix Mechanotransduction

Advanced Materials, EarlyView.
The graphical abstract shows how individual triggers (force, light, or temperature) and combined optothermal or receptor‐targeted actuation induce material responses at the tissue, cellular, and receptor scales. Their spatial (global or focused) and temporal (continuous or cyclic) modulation determines the resulting mechanical output.
Yi‐Tung Lu, Alison E. John, Marc A. Fernández‐Yagüe   +2 more
wiley   +1 more source

Circulating tumor cells clusters and their role in Breast cancer metastasis; a review of literature

Discover Oncology
AbstractBreast cancer is a significant and deadly threat to women globally. Moreover, Breast cancer metastasis is a complicated process involving multiple biological stages, which is considered a substantial cause of death, where cancer cells spread from the original tumor to other organs in the body—representing the primary mortality factor ...
Zeinab S. Sayed, Mohamed G. Khattap, Mostafa A. Madkour, Noha S. Yasen, Hanan A. Elbary, Reem A. Elsayed, Dalia A. Abdelkawy, Al-Hassan Soliman Wadan, Islam Omar, Mohamed H. Nafady   +9 more
openaire   +3 more sources

“Activation‐Resistance Elimination” Regulation by Lanthanide/Transition Metal Ion‐Coordinated Nanostructures Intensifies Cuproptosis and Tumor Immunotherapy

Advanced Materials, EarlyView.
The lanthanide/transition metal ion coordination nanoparticles, La‐Cu@Lap/IWR‐1, with optimized coordination, have been proven to achieve remarkable results in realizing comprehensive tumor cuproptosis through efficient cuproptosis activation and multidimensional resistance elimination, thereby synchronously realizing the synergistic antitumor effects ...
Junrong Wang, Mengqian Xu, Huaping Zhao, Yulin Xie, Guoqing Zhu, Haoze Li, Qianqian Sun, Yong Lei, Chunxia Li   +8 more
wiley   +1 more source

Adhesion of pancreatic tumor cell clusters by desmosomal molecules enhances early liver metastases formation

Scientific Reports
Desmosomes are intercellular adhesion complexes providing mechanical coupling and tissue integrity. Previously, a correlation of desmosomal molecule expression with invasion and metastasis formation in several tumor entities was described together with a
Niclas Dietrich, Ramon Castellanos-Martinez, Julia Kemmling, Arnd Heuser, Michael Schnoor, Camilla Schinner, Volker Spindler   +6 more
doaj   +1 more source

Biomimetic Immuno-Magnetosomes for High-Performance Enrichment of Circulating Tumor Cells

, 2016
A novel biomimetic immuno-magnetosome (IMS) is developed by coating a leukocyte membrane (decorated with anti-epithelial cell-adhesion molecule antibody) on a magnetic nanocluster. In addition to the good stability and magnetic controllability, the IMS
Zhao, Dongxu, Yue, Hua, Wang, Shumin, Jin, Yongjie, Xie, Hai-Yan, Wei, Wei, Wang, Shuang, Gao, Xiaoyong, Qiao, Chenmeng, Ma, Guanghui, Xiong, Ke   +10 more
core   +1 more source

In‐House Manufacturing of 3D ECM Culture Chips via Vacuum Thermoforming for Enhanced Imaging Applications

Advanced Materials Technologies, EarlyView.
Desktop vacuum thermoforming enables rapid, low‐cost fabrication of 96‐channel polystyrene culture chips with very thin imaging interfaces. The resulting platform supports cell lines, primary cells, and patient‐derived organoids, and enables high‐resolution confocal microscopy and single‐cell visualization, providing an accessible approach for advanced
Aleksandra Fomina, Adam Tam, Jennifer Lam, Nila C. Wu, Nancy T. Li, Alison P. McGuigan   +5 more
wiley   +1 more source

Regulating chemoresistance and cancer stemness: the CDH17-YAP pathway in distinct cellular states of lung cancer CTC clusters

Cellular & Molecular Biology Letters
Background Drug resistance in metastatic lung cancer significantly contributes to patient mortality. This study explores the role of circulating tumor cells (CTCs), the precursors to metastasis, in driving this resistance.
Zujun Que, Dan Qi, Yun Yang, Wang Yao, Jiajun Liu, Yan Li, Yuanyuan Yu, Luyao Wang, Fangfei Li, Ge Zhang, Erxi Wu, Jianhui Tian   +11 more
doaj   +1 more source

Recent Advances in Transparent Microelectrode Device Architecture and Fabrication Strategies for Biomedical Applications

Advanced Materials Technologies, EarlyView.
Transparent microelectrode arrays enable simultaneous optical and electrical electrophysiology with high spatiotemporal resolution, allowing multimodal observations of dynamic biological systems. Advances in materials and device architectures improve device performance by addressing key trade‐offs between optical transparency, impedance, and ...
Michael Abraham Listyawan, Tran Bach Dang, Chi Cong Nguyen, Yee Lap Pong, Tianruo Guo, Thanh Nho Do, Hoang‐Phuong Phan   +6 more
wiley   +1 more source

The concomitant tumor suspension cells derived from SKBR-3 exhibit circulating tumor cell features

Metastatic diseases are the major causes of cancer related deaths. Circulating tumor cells are important mediators for distant metastases. However, knowledge about circulating tumor cells is still limited due to their small quantity, lack of explicit ...
Wu, Jun, Li, Daiye, Liu, Feihong, Zhao, Xiaoli, Li, Shanshan, Yeung, Kelvin Wai Kwok, Wong, Tak Man   +6 more
core   +1 more source