A Unified Taxonomy for the Circulating Tumor Microenvironment (cTME) and Circulating Tumor-Associated Cells (C-TACs): A Conceptual Framework for Precision Oncology. [PDF]
CellsSawabata N.
europepmc +1 more source
A Dissociation-Based Seahorse XF Workflow for Quantifying Averaged Bioenergetics in Anchorage-Independent Cancer Cell Clusters. [PDF]
Bio ProtocLindeque R +3 more
europepmc +1 more source
Clusters of circulating tumor cells traverse capillary-sized vessels [PDF]
Proceedings of the National Academy of Sciences of the United States of America, 2016 Multicellular aggregates of circulating tumor cells (CTC clusters) are potent initiators of distant organ metastasis. However, it is currently assumed that CTC clusters are too large to pass through narrow vessels to reach these organs.
Ryan J Sullivan +2 more
exaly +6 more sources
Circulating tumor cell clusters: Insights into tumour dissemination and metastasis [PDF]
Expert Review of Molecular Diagnostics, 2020 Introduction: Metastasis results in more than 90% of cancer-related deaths globally. The process is thought to be facilitated by metastatic precursor cells, commonly termed circulating tumor cells (CTCs). CTCs can exist as single cells or cell clusters and travel through the lymphovasculature to distant organs where they can form overt metastasis ...
Majid Ebrahimi Warkiani +2 more
exaly +6 more sources
Clusters of circulating tumor cells: A biophysical and technological perspective [PDF]
Current Opinion in Biomedical Engineering, 2017 The vast majority of cancer associated deaths result from metastasis, yet the behaviors of its most potent cellular driver, circulating tumor cell clusters, are only beginning to be revealed. This review highlights recent advances to our understanding of tumor cell clusters with emphasis on enabling technologies.
Shannon L Stott, Jon F Edd, Mehmet Toner
exaly +3 more sources
High-Throughput Label-Free Isolation of Heterogeneous Circulating Tumor Cells and CTC Clusters from Non-Small-Cell Lung Cancer Patients [PDF]
Cancers, 2020 (1) Background: Circulating tumor cell (CTC) clusters are emerging as clinically significant harbingers of metastases in solid organ cancers. Prior to engaging these CTC clusters in animal models of metastases, it is imperative for technology to identify
Eric Lin +2 more
exaly +4 more sources
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Cluster circulating tumor cells in surgical cases of lung cancer
General Thoracic and Cardiovascular Surgery, 2020A cancer lesion sheds tumor cells into the circulating blood as circulating tumor cells (CTCs). Since cluster CTCs have been considered as precursor lesions of metastasis, their clinical implication was investigated in this study according to the preoperative status of cluster CTC detection in surgical cases of clinically early-stage lung cancer.Among ...
Noriyoshi Sawabata +5 more
openaire +2 more sources