Results 251 to 260 of about 39,675 (281)
Some of the next articles are maybe not open access.
Cluster circulating tumor cells in surgical cases of lung cancer
General Thoracic and Cardiovascular Surgery, 2020A cancer lesion sheds tumor cells into the circulating blood as circulating tumor cells (CTCs). Since cluster CTCs have been considered as precursor lesions of metastasis, their clinical implication was investigated in this study according to the preoperative status of cluster CTC detection in surgical cases of clinically early-stage lung cancer.Among ...
Noriyoshi Sawabata +5 more
openaire +2 more sources
Circulating Tumor Cell Cluster Sorting by Size and Asymmetry
2023Circulating tumor cell (CTC) clusters are rare yet potent initiators of metastasis and may be useful as clinical biomarkers. Numerous techniques have been developed to isolate individual circulating tumor cells from the blood, but these techniques are often ineffective at capturing CTC clusters and may cause cluster damage or dissociation during ...
openaire +2 more sources
Breast Cancer Research and Treatment, 2021
Cancer-associated fibroblasts (CAFs) are recruited to the tumor microenvironment (TME) and are critical drivers of breast cancer (BC) malignancy. Circulating tumor cells (CTCs) travel through hematogenous routes to establish metastases. CTCs circulate both individually and, more rarely, in clusters with other cell types.
Utsav Sharma +9 more
openaire +2 more sources
Cancer-associated fibroblasts (CAFs) are recruited to the tumor microenvironment (TME) and are critical drivers of breast cancer (BC) malignancy. Circulating tumor cells (CTCs) travel through hematogenous routes to establish metastases. CTCs circulate both individually and, more rarely, in clusters with other cell types.
Utsav Sharma +9 more
openaire +2 more sources
Circulating tumor cell clusters-associated gene plakoglobin and breast cancer survival
Breast Cancer Research and Treatment, 2015Breast cancer recurrence is a major cause of the disease-specific death. Circulating tumor cells (CTCs) are negatively associated with breast cancer survival. Plakoglobin, a cell adhesion protein, was recently reported as a determinant of CTCs types, single or clustered ones.
Lingeng, Lu +3 more
openaire +2 more sources
Circulating tumor cell clusters exhibit enhanced immune evasion from natural killer cells
The Journal of Immunology, 2020Abstract During cancer metastasis, the ability to evade immunosurveillance is key to the survival of circulating tumor cells (CTCs). Recent studies have found that in addition to single CTCs, multicellular clusters of CTCs can be detected in patient blood.
Hin Ching Lo +11 more
openaire +1 more source
Abstract IA009: Biology and vulnerabilities of circulating tumor cell clusters
Cancer Research, 2023Abstract The metastatic spread of cancer occurs through the generation and hematogenous dissemination of circulating tumor cells (CTCs). Among these, CTC clusters have recently emerged as key players in the metastatic process. With a combination of microfluidic technologies and single cell-resolution molecular analysis applied to cancer ...
openaire +1 more source
Advanced Healthcare Materials
AbstractDuring metastasis, circulating tumor cells (CTCs) can travel in the bloodstream as individual cells or clusters, associated with fibrin and platelets. Clusters have a higher metastatic potential due to their increased ability to withstand shear stress and arrest in small vessels.
Brian Schnoor +5 more
openaire +2 more sources
AbstractDuring metastasis, circulating tumor cells (CTCs) can travel in the bloodstream as individual cells or clusters, associated with fibrin and platelets. Clusters have a higher metastatic potential due to their increased ability to withstand shear stress and arrest in small vessels.
Brian Schnoor +5 more
openaire +2 more sources
Modeling the dynamics of circulating tumor cell clusters inside a microfluidic channel
BiomicrofluidicsCirculating tumor cells are central to metastasis, a particularly malign spread of cancer beyond its original location. While rare, there is growing evidence that the clusters of circulating tumor cells are significantly more harmful than individual cells.
Emmanuel I. Ezeobidi +1 more
openaire +2 more sources