Advanced Healthcare Materials, EarlyView.Bone fracture healing is a complex, timely orchestrated scenario involving multiple cell types and a plethora of cytokines and regulatory factors. To gain further insight, an in vitro model to a) study macrophage polarization under mechanical load in a fibrin hydrogel and b) subsequently assess the effect of conditioned media derived from macrophages ...
Anne Géraldine Guex +4 more
wiley +1 more source
The role of circulating tumor cells in shaping the future of early-stage lung cancer treatment: a clinical point of view. [PDF]
J Liq BiopsyLococo F +10 more
europepmc +1 more source
Multifunctional Biomedical Devices with Closed‐Loop Systems for Precision Therapy
Advanced Healthcare Materials, EarlyView.This review explores two major types of closed‐loop therapeutic systems: self‐sustained and externally triggered. It highlights recent advances in stimuli‐responsive materials, integrated bioelectronics, and data‐driven control strategies, offering insight into emerging strategies for personalized, responsive drug delivery.
Yixuan Leng, Rujie Sun
wiley +1 more source
Rolling Ultrasharp Microneedle Spheres Enable Topical Delivery of Biologics Through the Skin
Advanced Healthcare Materials, EarlyView.Rolling ultraminiaturized microneedle spheres (RUMS), created via two‐photon polymerization, unlock effective and painless topical delivery of messenger RNA (mRNA) and drugs through the skin. By gently forming thousands of microscopic pores, RUMS boost skin permeability by up to 100‐fold.
Theocharis Nikiforos Iordanidis +6 more
wiley +1 more source
Circulating Tumor Cells and Cancer Stem Cells: Clinical Implications in Nonmetastatic Breast Cancer
Breast Cancer: Basic and Clinical Research, 2016 M. Sayed +3 more
doaj
Simultaneous expression of epithelial and immune cell markers in circulating tumor cells identified in patients with stage 4 breast cancer. [PDF]
Commun Med (Lond)Higa N +13 more
europepmc +1 more source
Advanced Healthcare Materials, EarlyView.A new perspective for treatment of gastric cancer is proposed utilizing 4D printing to develop shape morphing, deployable, and magnetically guided local drug releasing patches. The deployed patches are envisioned to adhere at the tumor site to locally deliver high drug amounts.
Dina B. Mahmoud +3 more
wiley +1 more source
Identification of circulating tumor cells marker genes as prognostic signature in triple-negative breast cancer. [PDF]
Discov OncolHu J, Zhang KM, Wang X.
europepmc +1 more source
Cell Calcification Models and Their Implications for Medicine and Biomaterial Research
Advanced Healthcare Materials, EarlyView.Calcification, is the process by which the tissues containing minerals are formed, occurring during normal physiological processes, or in pathological conditions. Here, it is aimed to give a comprehensive overview of the range of cell models available, and the approaches taken by these models, highlighting when and how methodological divergences arise,
Luke Hunter +5 more
wiley +1 more source