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Research Progress of Noninvasive Evaluation of Portal Hypertension by Blood‐Based Tests
Portal Hypertension & CirrhosisPortal hypertension (PH) is a collection of clinical conditions that occur due to an enduring elevation of pressure within the portal venous system, and it is closely linked to the prognosis of liver disease patients. The hepatic venous pressure gradient
Wei Chen +10 more
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The incidence of portal vein thrombosis at liver transplantation [PDF]
, 1992 The incidence of portal vein thrombosis was examined in 885 patients who received orthotopic liver transplantations for various end‐stage liver diseases between 1989 and 1990. The thrombosis was classified into four grades.
Iwatsuki, S +3 more
core +1 more source
Advanced Science, EarlyView.Within the hepatitis E virus (HEV) ORF1 polyprotein, the X domain interacts with viral RNA‐dependent RNA polymerase (RdRp), forming a functional “pocket‐like” cavity (PC) that is crucial for viral replication. Structure‐based screening, surface plasmon resonance (SPR) assays, and HEV model validation collectively identify saikosaponin D and ...
Xiaohui Ding +15 more
wiley +1 more source
Stem Cells International, 2016 Profibrogenesis cytokine, transforming growth factor- (TGF-) β1, induces hepatic progenitors experiencing epithelial to mesenchymal transition (EMT) to matrix synthesis cells, even tumor initiating cells.
Ping Wang +11 more
doaj +1 more source
An Analysis of Immunoreactive Signatures in Early Stage Hepatocellular Carcinoma
EBioMedicine, 2015 Background: Hepatocellular carcinoma (HCC) is prevalent worldwide and early diagnosis of HCC is critical for effective treatment and optimal prognosis.
Yu Hong +26 more
doaj +1 more source
Non cell autonomous upregulation of CDKN2 transcription linked to progression of chronic hepatitis C disease [PDF]
, 2013 Chronic hepatitis C virus infection (C-HC) is associated with higher mortality arising from hepatic and extrahepatic disease. This may be due to accelerated biological aging; however, studies in C-HC have thus far been based solely on telomere length as ...
Barclay, Stephen +7 more
core +2 more sources
Effect of alcohol on clinical complications of hepatitis virus-induced liver cirrhosis: a consecutive ten-year study [PDF]
, 2022 Kodjo-Kunale Abassa +5 more
openalex +1 more source
Navigating Transition Metal‐Dependent Cell Death: Mechanisms, Crosstalk, and Future Directions
Advanced Science, EarlyView.Transition metals trigger distinct regulated cell death pathways beyond traditional apoptosis. This review examines ferroptosis (iron‐catalyzed lipid peroxidation) and cuproptosis (copper‐induced mitochondrial proteotoxicity), while exploring hypothetical “cobaltosis” as a novel pathway.
Qinghang Song, Yuxuan Yang, Lina Yang
wiley +1 more source
International Journal of Infectious Diseases, 2018 Background: The numbers of articles reporting randomized controlled trials (RCTs) on viral hepatitis in China have been increasing, but there have been few systematic studies evaluating the reporting quality of RCTs in this field.
Na Zeng +7 more
doaj +1 more source
Value of Ascitic Lipids in the Differentiation between Cirrhotic and Malignant Ascites [PDF]
, 1986 Ascitic fluid concentrations of cholesterol, triglycerides and phospholipids, were compared with ascitic fluid total protein in 40 patients with chronic liver disease, 51patients with various neoplasms and 1 patient with cardiac failure.
Alexander L. Gerbes +22 more
core +1 more source