The structure of TTHA0988 from Thermus thermophilus, a KipI-KipA homologue incorrectly annotated as allophanate hydrolase [PDF]
The Thermus thermophilus protein TTHA0988 is a protein of unknown function which represents a fusion of two proteins found almost ubiquitously across the bacterial kingdom.
Guss, J. Mitchell +5 more
core +2 more sources
Mapping molluscan endocrinology: a systematic and critical appraisal
ABSTRACT Historically, a vertebrate‐centric paradigm has framed our interpretation of molluscan endocrinology, with considerable research focusing on vertebrate‐type steroid hormones (e.g. oestrogens, testosterone). However, contradictory evidence on the occurrence of vertebrate‐type steroid hormones in molluscan tissues, and a lack of the specific ...
Konstantinos Panagiotidis +3 more
wiley +1 more source
Solution structural analysis of the single-domain parvulin TbPin1. [PDF]
Pin1-type parvulins are phosphorylation-dependent peptidyl-prolyl cis-trans isomerases. Their functions have been widely reported to be involved in a variety of cellular responses or processes, such as cell division, transcription, and apoptosis, as well
Lifang Sun +6 more
doaj +1 more source
Investigating ‘rhomboid’ membrane proteases’ roles in development and signalling in Dictyostelium [PDF]
The rhomboid family of intramembrane serine proteases is almost ubiquitous across all kingdoms of life. The enzymes are poorly conserved at sequence level but are similar in their structures and active-site motifs.
Rafiq, Mehak +2 more
core
ABSTRACT Background Triple‐negative breast cancer (TNBC) is known for its more aggressive clinical behavior, poor prognosis, and distinctive patterns of metastasis. Neoadjuvant chemotherapy (NAC) can influence both tumor cells and the tumor microenvironment.
Moazzam Ali Shahid +5 more
wiley +1 more source
Molecular Mechanisms Underlying Root Nodule Formation and Activity
Symbiotic interactions between legumes and a group of soil bacteria, known as rhizobia, lead to the formation of a specialized organs called root nodules.
Katarzyna Nuc, Przemysław Olejnik
doaj +1 more source
Cj0596 is a periplasmic peptidyl prolyl cis-trans isomerase involved in Campylobacter jejuni motility, invasion, and colonization [PDF]
Background Campylobacter jejuni is a gastrointestinal pathogen of humans, but part of the normal flora of poultry, and therefore grows well at the respective body temperatures of 37°C and 42°C. Proteomic studies on temperature regulation in C.
Kimberly M Rathbun +2 more
core +1 more source
ABSTRACT Alzheimer's disease (AD) is a neurodegenerative disorder characterized by cognitive decline and pathological protein aggregation. Comprehensive quantitative proteomics of brain tissues from AD patients is critical for pursuing a better understanding of the molecular mechanisms that drive AD progression.
Mehrdad Falamarzi Askarani +3 more
wiley +1 more source
Analysis of barley leaf epidermis and extrahaustorial proteomes during powdery mildew infection reveals that the PR5 thaumatin-like protein TLP5 is required for susceptibility towards Blumeria graminis f. sp. hordei [PDF]
Powdery mildews are biotrophic pathogens causing fungal diseases in many economically important crops, including cereals, which are affected by Blumeria graminis.
Aguilar +83 more
core +1 more source
Abstract The isoproterenol‐induced myocardial infarction model is a well‐established experimental approach for studying cardiac injury and testing potential protective treatments. By overstimulating beta‐adrenergic receptors, this model closely reproduces key features of human heart attacks, including oxidative damage, calcium imbalance, inflammatory ...
Bushra Imran +5 more
wiley +1 more source

