Results 61 to 70 of about 19,804 (171)

CYP2C19 Genotype is Associated with Citalopram Treatment Outcomes in a Real‐World Setting

Clinical Pharmacology &Therapeutics, Volume 120, Issue 2, Page 412-419, August 2026.
CYP2C19 metabolizes various selective serotonin reuptake inhibitors (SSRIs) and genetic CYP2C19 variants are associated with SSRI tolerability and response. Yet, whether CYP2C19 variability also impacts citalopram response remained unclear. We here evaluated associations between CYP2C19 genotypes and citalopram prescription data of 11,079 patients from
Yoomi Park, Yitian Zhou, Volker M. Lauschke   +2 more
wiley   +1 more source

The additive effect between citalopram and muscimol upon induction of antinociceptive effect in male mice

IBRO Neuroscience Reports
Previous investigations have revealed the role of GABAergic and serotonergic systems in the modulation of pain behavior. This research aimed to examine the effects of intracerebroventricular (i.c.v.) infusion of GABAA receptor agonist and antagonist as ...
Taha Shokrnejad-namin, Elnaz Amini, Fatemeh Khakpai, Mohammad-Reza Zarrindast   +3 more
doaj   +1 more source

Investigation of the In Vitro and In Vivo Metabolism and μ‐Opioid Receptor Affinity of the Nitazene N‐Pyrrolidino Fluetonitazene

Drug Testing and Analysis, Volume 18, Issue 8, Page 1097-1113, August 2026.
Eight metabolites for N‐pyrrolidino fluetonitazene were identified in vitro, three of which (M2, M6 and M8) were present in an authentic urine sample. M2 was the most abundant in vivo metabolite and is a common marker metabolite of nitazepyne‐type substances.
Severin Zemp, Gaia Alluisetti, Wolfgang Weinmann, Bettina Schrag, Frank Sporkert, Maurine Leclerc, Katharina Elisabeth Grafinger   +6 more
wiley   +1 more source

The effectiveness and limitations of regulatory warnings for the safe prescribing of citalopram

Drug, Healthcare and Patient Safety, 2015
Kevin J Friesen, Shawn C BugdenFaculty of Health Sciences, College of Pharmacy, University of Manitoba, Winnipeg, MB, CanadaBackground: Citalopram is the most commonly prescribed antidepressant in Canada.
Friesen KJ, Bugden SC
doaj  

Neurotoxicity and PRES after severe citalopram intoxication in a 12-months-old baby

Emergency Care Journal
Citalopram intoxications can lead to Serotonin Syndrome (SS) development, characterized by altered mental status, seizures, autonomic instability, hyperthermia and extrapyramidal signs.
Sara Minghetti, Alessandra Lazzerotti, Debora Sala, Chiara Vimercati , Sofia Giudici, Santa Florio, Francesca Formica, Stefania Zambrano, Nivedita Agarwal, Cinzia Peruzzi   +9 more
doaj   +1 more source

Changes in electrical activity of heart during ischemic–reperfusion injury modified by the administration of antidepressants

European Pharmaceutical Journal, 2016
The aim of our work was to investigate the effect of amitriptyline, citalopram and venlafaxine on the heart during ischemic- reperfusion (l-R) injury.
Vicen M., Gulač P., Stankovičová T.
doaj   +1 more source

Exploring Cerumen as an Alternative Matrix for Drug Detection and Quantification: Method Development and Application in Clinical Samples

Drug Testing and Analysis, Volume 18, Issue 8, Page 1065-1075, August 2026.
An LC–MS/MS method was developed for the detection of 33 psychoactive medications in cerumen (earwax) and applied to the samples of 60 psychiatric inpatient volunteers. The findings highlighted the utility of cerumen as an innovative biospecimen in clinical toxicological analysis.
Dimitrios Phaedon Kevrekidis, Helen G. Gika, Georgios Panagiotoglou, Eleni Parlapani, Pavlos Pavlidis, Nikolaos Raikos   +5 more
wiley   +1 more source

Diplopia; an Adverse Effect of Citalopram

Pharmaceutical and Biomedical Research, 2019
Citalopram, a selective serotonin reuptake inhibitor (SSRI), was approved by the Food and Drug Administration in 1998 as a safe and well-tolerated antidepressant; the use of it may result in rare and sometimes dangerous side effects.
Seyed Hamzeh Hosseini, Amirhossein Ahmadi   +1 more
doaj  

Relationship Between Sexual Attitude and Sexual Function Among Iranian Women and Men During Pregnancy: A Cross‐Sectional Study

Health Science Reports, Volume 9, Issue 8, August 2026.
ABSTRACT Background and Aims Sexual function is considered an essential criterion for enhancing the quality of life, encompassing not only the genital component but also mental and physical factors. The present study was conducted to determine the relationship between sexual attitude and sexual function among Iranian women and men during pregnancy ...
Sepideh Mashayekh‐Amiri, Mobina Ahmadi, Elnaz Hemati, Mojgan Mirghafourvand   +3 more
wiley   +1 more source

Patterns in (es)citalopram prescriptions to Medicaid and Medicare patients in the United States: the potential effects of evergreening

Frontiers in Psychiatry
IntroductionCitalopram and escitalopram are among the most used medications and are key treatments for many psychiatric disorders. Previous findings suggest citalopram and escitalopram prescription rates are changing because of the patent for citalopram ...
Luke R. Cavanah, Parita K. Ray, Jessica L. Goldhirsh, Leighton Y. Huey, Leighton Y. Huey, Brian J. Piper, Brian J. Piper   +6 more
doaj   +1 more source