Results 71 to 80 of about 19,804 (171)

Inverse‐Intensity‐Weighted Generalized Estimating Equations With Irregularly Measured Longitudinal Data and Informative Dropout

Statistics in Medicine, Volume 45, Issue 18-19, August 2026.
ABSTRACT Longitudinal data are commonly encountered in biomedical research, including randomized trials and retrospective cohort studies. Subjects are typically followed over a period of time and may be scheduled for follow‐up at predetermined time points.
George Stefan, Eleanor Pullenayegum
wiley   +1 more source

Selective Serotonin Reuptake Inhibitor Treatment in Adolescence and Subsequent Risk of Nonaffective Psychosis: A Quasi‐Experimental Study

Acta Psychiatrica Scandinavica, Volume 154, Issue 2, Page 153-162, August 2026.
ABSTRACT Objective Psychotic disorders are frequently preceded by common mental disorders (CMDs), like depression and anxiety. It remains unclear whether treating CMDs in adolescence can reduce subsequent psychosis risk. We applied quasi‐experimental methods to national register data to assess whether a causal relationship exists between selective ...
Ioanna Kougianou, Animesh Talukder, Kirstie O′ Hare, Colm Healy, Ian Kelleher   +4 more
wiley   +1 more source

Combination of Citalopram and Nortriptyline in Treatment of Moderate to Severe Major Depression: A Double-blind, Placebo- controlled Trial [PDF]

Iranian Journal of Psychiatry, 2006
Objective: Depression is a major health problem, which is not only underrecognized and undertreated, but is also associated with significant morbidity and mortality.
Mohammad Reza Mohammadi, Abbas Ali Nasehi, Nastaran Habibi, Firoozeh Raisi   +3 more
doaj   +1 more source

Lithium Dispensing Patterns in Dutch Youth: Prevalence, Incidence Dosages, and Duration of Use From 2011 to 2022

Bipolar Disorders, Volume 28, Issue 5, August 2026.
ABSTRACT Objective Bipolar disorder (BD) often emerges during mid‐adolescence and young adulthood, and leads to functional and social impairment, with a prevalence of 0.87% among Dutch youth. Lithium, the first‐line BD maintenance treatment, stabilizes mood, prevents suicide, and is well tolerated, yet its use has declined as long‐term second ...
Ravish N. Gangapersad, Lisa T. Ringeling, Jens H. J. Bos, Birgit C. P. Koch, Manon H. J. Hillegers, Pilar Garcia‐Gomez, Catharina C. M. Schuiling‐Veninga, Eelko Hak, Bram Dierckx   +8 more
wiley   +1 more source

CYP2C19 c.681G>A Is not in Complete Linkage Disequilibrium With c.332‐23A>G: Implications for Pharmacogenetic Testing

Clinical and Translational Science, Volume 19, Issue 8, August 2026.
ABSTRACT CYP2C19 plays an important role in the metabolism of many medications, including the antiplatelet agent clopidogrel, the antifungal agent voriconazole, selective serotonin reuptake inhibitors, select tricyclic antidepressants, and proton pump inhibitors.
Amy J. Turner, Erin C. Boone, Cyrine E. Haidar, Wenjian Yang, Ashley D. Derezinski, Andrew Haddad, Philip E. Empey, Ulrich Broeckel, Andrea Gaedigk   +8 more
wiley   +1 more source

Risk of Psychiatric Worsening With GLP‐1 Receptor Agonist Use in Patients With Type 2 Diabetes and Treated Depression

Diabetes, Obesity and Metabolism, Volume 28, Issue 8, Page 7048-7057, August 2026.
ABSTRACT Aims To compare 1‐year psychiatric outcomes after GLP‐1 receptor agonist (GLP‐1 RA) versus sodium‐glucose cotransporter‐2 inhibitor (SGLT2i) initiation in patients with type 2 diabetes and treated depression. Materials and Methods We conducted a retrospective active‐comparator, new‐user cohort study using electronic health records from the ...
Yu Chang, Ming‐Hong Hsieh, Po‐Chung Ju, Cheng‐Chen Chang   +3 more
wiley   +1 more source

Prescribing Practice of Citalopram and Escitalopram in Older Adults Following the 2014 MHRA Guidance of Associated QTc Prolongation: A Clinical Audit

BJPsych Open
Aims Citalopram and escitalopram are commonly used serotonin-specific reuptake inhibitors (SSRIs) for the treatment of depression and anxiety. These medications are known to cause corrected QT interval (QTc) prolongation, with risks of further ...
Shreyan Kar, Aparna Prasanna
doaj   +1 more source

Chemie und Pharmazie in die Nachhaltigkeit einbetten

Angewandte Chemie, Volume 138, Issue 29, 13 July 2026.
Chemie und Pharmazie sind mit ihren Produkten und Prozessen grundlegend für unseren hohen Lebensstandard. Es ist wesentlich, ihre Verbindung mit der Nachhaltigkeit zu verstehen, damit sie auf nachhaltige Weise nachhaltig zur Nachhaltigkeit beitragen können.
Klaus Kümmerer
wiley   +1 more source

Embedding Chemistry and Pharmacy Into Sustainability

Angewandte Chemie International Edition, Volume 65, Issue 29, 13 July 2026.
Chemistry and pharmacy provide products and processes that are indispensable for our high living standard. To understand their relationship with sustainability is important to allow them to contribute to sustainability in a sustainable manner. An integrated overview of green, circular, and sustainable chemistry and pharmacy is given and how they have t
Klaus Kümmerer
wiley   +1 more source

Sertraline, citalopram and paroxetine in lactation: passage into breastmilk and infant exposure

Frontiers in Pharmacology
ObjectivesThis study aimed to investigate the plasma and breastmilk concentrations for sertraline, citalopram and paroxetine for assessment of the Milk/Plasma (M/P) ratio and Absolute Infant Dose (AID), and to determine actual infant drug exposure ...
Daphne Den Besten-Bertholee, Daan J. Touw, Daan J. Touw, Elvera A. Damer, Paola Mian, Paola Mian, Peter G. J. Ter Horst   +6 more
doaj   +1 more source