Results 81 to 90 of about 6,727 (271)

Role of Citicoline in the Management of Traumatic Brain Injury

open access: yesPharmaceuticals, 2021
Head injury is among the most devastating types of injury, specifically called Traumatic Brain Injury (TBI). There is a need to diminish the morbidity related with TBI and to improve the outcome of patients suffering TBI.
Julio J. Secades
doaj   +1 more source

A Hypothesis: Metabolic Contributions to 16p11.2 Deletion Syndrome

open access: yesBioEssays, Volume 47, Issue 3, March 2025.
16p11.2 Deletion syndrome is associated with brain, body, and behavioral symptoms. A majority of 16p11.2 genes relate to metabolism, involving amino acids/proteins, DNA, RNA, catabolism, lipids, and carbohydrates. Additional contributions include changes in cell structure, signaling, development, immune system, nervous system, and localization.
Brandon Kar Meng Choo   +2 more
wiley   +1 more source

Cognitive Sequelae of COVID‐19: Mechanistic Insights and Therapeutic Approaches

open access: yesCNS Neuroscience &Therapeutics, Volume 31, Issue 3, March 2025.
Post‐COVID‐19 neurological syndrome, marked by cognitive dysfunction, stems from mechanisms like neuroinflammation, cerebrovascular injury, and psychological stress. This review highlights pharmacological treatments and cognitive rehabilitation as promising strategies to address cognitive impairment from acute COVID‐19 to long‐COVID phases.
Yu‐Hao Chen   +8 more
wiley   +1 more source

Efficacy of citicoline as a supplement in glaucoma patients: A systematic review.

open access: yesPLoS ONE, 2023
PurposeGlaucoma is a leading cause of irreversible blindness worldwide. Retinal ganglion cells (RGC), the neurons that connect the eyes to the brain, specifically die in glaucoma, leading to blindness.
Julia Prinz   +5 more
doaj   +1 more source

Concurrent Intravenous Drug Administration to the Critically Ill: Compatibility of Ginkgo Biloba Extract With Frequently Used Drugs in the Neurological Intensive Care Unit

open access: yesJournal of Clinical Pharmacy and Therapeutics, Volume 2025, Issue 1, 2025.
Objective Ginkgo biloba extract (EGB), a traditional Chinese medicine extracted from the Ginkgophyta, was used to regulate various neurological disorders (NDs). Limited compatibility data exist on EGB after marketing with other drugs administered simultaneously through the Y‐site.
Haiwen Ding   +7 more
wiley   +1 more source

Relative Efficacy of Piracetam, Modafinil and Citicoline on Cognitive Function in an Animal Model [PDF]

open access: yesJournal of Clinical and Diagnostic Research, 2017
Introduction: Nootropic drugs or cognitive enhancers are pharmacological agents that improve cognitive function and memory by various mechanisms. Drugs like piracetam, modafinil and citicoline have been used as nootropic agents.
Farrukh Ahmad   +5 more
doaj   +1 more source

Cholinergic regulation of mood: from basic and clinical studies to emerging therapeutics. [PDF]

open access: yes, 2019
Mood disorders are highly prevalent and are the leading cause of disability worldwide. The neurobiological mechanisms underlying depression remain poorly understood, although theories regarding dysfunction within various neurotransmitter systems have ...
Dulawa, Stephanie C, Janowsky, David S
core  

Neuroprotection in stroke: past, present, and future. [PDF]

open access: yes, 2014
Stroke is a devastating medical condition, killing millions of people each year and causing serious injury to many more. Despite advances in treatment, there is still little that can be done to prevent stroke-related brain damage.
Majid, A.
core   +3 more sources

Effect of Ripasudil on the Change Rates of the Circumpapillary Retinal Nerve Fiber Layer Thickness in Patients With Primary Open‐Angle Glaucoma

open access: yesJournal of Ophthalmology, Volume 2025, Issue 1, 2025.
Purpose: The effect of the Rho‐kinase inhibitor ripasudil on the retinal optic nerve fiber layer (RNFL) remains unclear. We aimed to determine this effect in patients with primary open‐angle glaucoma (POAG) using optical coherence tomography (OCT) measurements and linear mixed analysis.
Katsumasa Sakurai   +8 more
wiley   +1 more source

Hypoxia/Aglycemia-induced endothelial barrier dysfunction and tight junction protein downregulation can be ameliorated by citicoline. [PDF]

open access: yesPLoS ONE, 2013
This study explores the effect of citicoline on the permeability and expression of tight junction proteins (TJPs) in endothelial cells under hypoxia/aglycemia conditions.
Xiaotang Ma   +6 more
doaj   +1 more source

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