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Citric Acid: Properties, Microbial Production, and Applications in Industries

Molecules, 2023
Citric acid finds broad applications in various industrial sectors, such as the pharmaceutical, food, chemical, and cosmetic industries. The bioproduction of citric acid uses various microorganisms, but the most commonly employed ones are filamentous ...
Ewelina Książek
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Citric acid promoted melanin synthesis in B16F10 mouse melanoma cells, but inhibited it in human epidermal melanocytes and HMV-II melanoma cells via the GSK3β/β-catenin signaling pathway.

PLoS ONE, 2020
Melanin, a pigment synthesized by melanocytes in the skin, resists the damage caused by ultraviolet rays to cells. Citric acid, a well-known food additive, is commonly used as an antioxidant and is an important part of the tricarboxylic acid (TCA) cycle ...
Siqi Zhou, Kazuichi Sakamoto
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Optimization of Citric Acid Production by Immobilized Cells of Novel Yeast Isolates

Mycobiology, 2020
Citric acid is a commercially valuable organic acid widely used in food, pharmaceutical, and beverage industries. In this study, 260 yeast strains were isolated from soil, bread, juices, and fruits wastes and preliminarily screened using bromocresol ...
Abd El-Latif Hesham, Yasser S. Mostafa, Laila Essa Omar AlSharqi   +2 more
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Systems metabolic engineering for citric acid production by Aspergillus niger in the post-genomic era

Microbial Cell Factories, 2019
Citric acid is the world’s largest consumed organic acid and is widely used in beverage, food and pharmaceutical industries. Aspergillus niger is the main industrial workhorse for citric acid production.
Zhenyu Tong, Xiaomei Zheng, Yi Tong, Yong-Cheng Shi, Jibin Sun   +4 more
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Production of high titer of citric acid from inulin

BMC Biotechnology, 2019
Background Citric acid is considered as the most economically feasible product of microbiological production, therefore studies on cheap and renewable raw materials for its production are highly desirable.
Magdalena Rakicka, Jakub Wolniak, Zbigniew Lazar, Waldemar Rymowicz   +3 more
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Assessment of biocompatibility for citric acid crosslinked starch elastomeric films in cell culture applications. [PDF]

Sci Rep
This study investigates the synthesis of potato starch elastomers reinforced with silicon dioxide (SiO2) and citric acid as a crosslinking agent to enhance their mechanical and barrier properties.
Pooja N, Ahmed NY, Mal SS, Bharath PAS, Zhuo GY, Noothalapati H, Managuli V, Mazumder N.   +7 more
europepmc   +2 more sources

CitGATA7 interact with histone acetyltransferase CitHAG28 to promote citric acid degradation by regulating the glutamine synthetase pathway in citrus. [PDF]

Mol Hortic
Organic acid is a crucial indicator of fruit quality traits. Citric acid, the predominant organic acid in citrus fruit, directly influences its edible quality and economic value.
Lin X, Li S, Shi Y, Ma Y, Li Y, Tan H, Zhang B, Xu C, Chen K.   +8 more
europepmc   +2 more sources

Chemical route for synthesis of citric acid from orange and grape juices [PDF]

Chemical Industry and Chemical Engineering Quarterly, 2022
Citrus fruits contain sufficient citric acid, which is the main tricarboxylic acid. The properties of citric acid make it an important additive in various process industries.
Naveen Prasad B.S., Sivamani Selvaraju, Cuento Azucena, Pachiyappan Senthilkumar   +3 more
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Citric Acid: A Multifunctional Pharmaceutical Excipient

Pharmaceutics, 2022
Citric acid, a tricarboxylic acid, has found wide application in the chemical and pharmaceutical industry due to its biocompatibility, versatility, and green, environmentally friendly chemistry.
M. Lambros, Thac (Henry) Tran, Q. Fei, M. Nicolaou   +3 more
semanticscholar   +1 more source

Citric Acid Influences the Dynamics of the Fermentation Quality, Protease Activity and Microbial Community of Mulberry Leaf Silage

Fermentation, 2021
Mulberry (Morus alba) leaves has performed well as a high-quality protein supplement for livestock and enriches the edible resources of livestock. However, the harvest of mulberry leaves is seasonal and occurs mainly during the rainy season in southeast ...
Dekui Chen, Wei Zhou, Xiang Guo, Mingyang Zheng, Xiaoyang Chen, Qing Zhang   +5 more
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