Results 161 to 170 of about 5,140,030 (336)

β‐Mangostin Attenuates TET2‐Mediated DNA Demethylation of Prkcg in the Prevention of Intervertebral Disc Degeneration

open access: yesAdvanced Science, EarlyView.
β‐Mangostin alleviates intervertebral disc degeneration through dual modulation of macrophage polarization and the TET2‐Prkcg axis in nucleus pulposus cells. Abstract Intervertebral disc degeneration (IDD) induced lower back pain is a main cause of disability, resulting in a substantial workforce loss worldwide and placing a substantial burden on the ...
Xiangzhen Kong   +15 more
wiley   +1 more source

Dynamic interaction of sweet and sour taste perceptions based on sucrose and citric acid. [PDF]

open access: yesNPJ Sci Food
Mao Y   +9 more
europepmc   +1 more source

Engineering Decavalent, Sperm‐Binding Laminin‐IgG Hybrid Antibodies for Potent Non‐Hormonal Contraception

open access: yesAdvanced Science, EarlyView.
This study investigates a highly multivalent mAb platform fusing Laminin‐511 heterotrimerization domains with Fabs and IgG1‐Fc as a non‐hormonal contraceptive. The most potent molecule ‘LamH10’, possessing 10 Fabs, rapidly achieved >99% reduction in progressively motile sperm at just 33µg per dose in sheep, making the laminin‐IgG hybrid platform the ...
Alison Schaefer   +8 more
wiley   +1 more source

Potent antimicrobial and antibiofilm activity of citric acid coated magnetite nanoparticles for leather preservation. [PDF]

open access: yesSci Rep
Hayat A   +7 more
europepmc   +1 more source

Spatiotemporal Adaptations‐Driven Dynamic Thra Activation Simulates a Skin Wound Healing Response

open access: yesAdvanced Science, EarlyView.
This study uncovers the thyroid hormone receptor Thra as a pivotal regulator that spatiotemporally orchestrates dual‐phase skin repair. Epidermal Thra accelerates barrier restoration via glutathione‐driven keratin assembly, while dermal Thra establishes angiogenic niches through SAA3‐FN1‐mediated matrix remodeling.
Zeming Li   +15 more
wiley   +1 more source

Structure‐Function Relationships of Biomass‐Derived Materials for Zinc Metal Protection

open access: yesAdvanced Science, EarlyView.
This review analyses the mechanism of zinc anode degradation, focuses on the protective roles of the four major functional groups of carboxyl, amino, hydroxyl, and sulfonic acid groups in biomass materials, reveals the structure‐function relationship and synergistic effects of functional groups, and looks forward to the challenges and directions of ...
Qiwei Gao   +4 more
wiley   +1 more source

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