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Citrullination and autoimmunity

Autoimmunity Reviews, 2015
Autoimmune diseases are characterized by the body's own immune system attack to the self-tissues, a condition enabled, in predisposed subjects, by the reduction of self-tolerance. A central role has been recently recognized to post-translational modifications, since they can promote generation of neo-(auto)antigens and in turn an autoimmune response ...
Guido Valesini, Cristina Iannuccelli
exaly   +4 more sources

Citrulline and the gut

Current Opinion in Clinical Nutrition and Metabolic Care, 2007
Citrulline, a nonprotein amino acid, is an important source of endogenous arginine. The gut is the main source of citrulline in humans. Hence, citrulline is a potential biomarker of short bowel function. Conversely, citrulline uptake by the gut is important for an oral supply of this amino acid as an alternative to arginine. This review discusses these
Emmanuel, Curis   +2 more
openaire   +2 more sources

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