Results 131 to 140 of about 9,594 (224)

Citrullination-associated transcriptional states identify a non-canonical invasive program in malignant epithelial cells and correlate with SPP1-CD44 immune microenvironment niches in thyroid cancer. [PDF]

Transl Oncol
Tian Z, Zhu P, Zhao X, Yang F.
europepmc   +1 more source

Mass spectrometry -based identification and quantification of posttranslational modification citrullination in rheumatoid arthritis

, 2019
Post-translational modifications (PTMs) of proteins and peptides modulate their behavior and are frequently implicated to physiological functions in a normal state, and to human diseases in aberrant states.
Sharma, Mandvi
core  

Mapping the Substrate Specificity Landscape of PAD2 and PAD4 Enzymes. [PDF]

Chembiochem
Borbély A, Steckel A, Papp D, Pál D, Uray K, Gőz VG, Schlosser G.   +6 more
europepmc   +1 more source

Breaking the glial loop: astrocytic PAD2 and citrullinated vimentin drive microglial dysfunction in Alzheimer's disease. [PDF]

Mol Neurodegener
Lam JYL, Bu G.
europepmc   +1 more source

Role of post-translational modifications in modulating histone reactivity in the extracellular environment. [PDF]

Biochem Soc Trans
Hemmling H, Hawkins CL.
europepmc   +1 more source

Neutrophil Extracellular Trap Formation-Derived Peptidylarginine Deiminases in the Citrullination of Oral Bacteria to Promote Inflammation in Rheumatoid Arthritis. [PDF]

J Rheumatol
Acharya S, Brewer RC, Gomez AM, Younis S, Pandit M, Jahanbani S, Sharpe O, Love ZZ, Howard MC, Orange DE, Robinson WH.   +10 more
europepmc   +1 more source

Alzheimer's disease: erasing the peptidyl-arginine deiminase 2 (PAD2) stamp to restore microglial defense. [PDF]

Signal Transduct Target Ther
Shen X, Wang S, Song W.
europepmc   +1 more source

Peptidylarginine deiminase 4-mediated citrullination in human disease: molecular mechanisms and therapeutic targeting. [PDF]

Front Pharmacol
Zou P, Su XD, Tian W, Xie XY, Yang K.
europepmc   +1 more source

NLRP3 inflammasome promotes PAD2/PAD4 release and protein citrullination in rheumatoid arthritis. [PDF]

Commun Biol
Zaranski KJ, Yang M, Scaletta LR, Darrah E, Ort T, Sims GP, Kuriakose T.   +6 more
europepmc   +1 more source

Molecular basis of post-translational neoantigen generation in rheumatoid arthritis: breaking immunological tolerance and implications for targeted therapy. [PDF]

Front Immunol
Pérez Linaza A, Picallo Díaz S, García IS, Yi W, Guerrero Lores Á, Aragón González JM, Garcia-Cozar F, Fernandez-Ponce C, Fernandez-Cisnal R.   +8 more
europepmc   +1 more source