Results 181 to 190 of about 37,088 (271)

Protective and Pathogenic Antibodies to Citrullinated Antigens

Immunological Reviews, Volume 342, Issue 1, September 2026.
ABSTRACT Autoimmune diseases start years before clinical onset. In rheumatoid arthritis (RA), autoantibodies to citrullinated proteins (ACPA) and to modified IgG (rheumatoid factors, RF) can be detected many years before the inflammatory attack on cartilaginous joints. It has been assumed that these antibodies are pathogenic.
Outi Sareila, Yibo He, Zhongwei Xu, Changrong Ge, Erik Lönnblom, Rikard Holmdahl   +5 more
wiley   +1 more source

Citrulline Measurement [PDF]

, 2020
openaire   +1 more source

Effects of Oral Care Intervention on Gingivitis-Mediated Induction of Nitric Oxide Synthesis and Oxidative Stress. [PDF]

Int J Mol Sci
Klukowska M, Xie S, Li L, Huggins T, Ashe J, Tan C, Circello B, Wei X, Ramji N, White DJ, Biesbrock AR.   +10 more
europepmc   +1 more source

Complement Activation by Post‐Translationally Modified Proteins: Links to Chronic Inflammation and Autoimmunity

Immunological Reviews, Volume 342, Issue 1, September 2026.
ABSTRACT Post‐translational modifications (PTMs) of proteins are essential to maintain homeostasis as many cellular processes rely on reversible PTMs. However, several PTMs, particularly irreversible PTMs in the extracellular space, can contribute to tissue dysfunction, inflammation, and may even trigger the development of autoimmunity against PTM ...
Marleen M. J. van Greevenbroek, Leendert A. Trouw   +1 more
wiley   +1 more source

Serum metabolomics signatures after an acute bout of combined traditional or high‐intensity tactical training in young adults

Physiological Reports, Volume 14, Issue 18, September 2026.
Abstract Alternative exercise prescriptions and doses would be expected to result in distinct signatures due to differences in duration and intensity. We tested two novel combined endurance and resistance exercise regimens to understand how differing prescriptions alter the timecourse of metabolomics response.
Zachary A. Graham, Khyatiben V. Pathak, Krystine Garcia‐Mansfield, Kaleen M. Lavin, Anakaren R. Torres, Jeremy S. McAdam, Timothy Broderick, Patrick Pirrotte, Marcas M. Bamman   +8 more
wiley   +1 more source

Evidence of Hypoxia Signaling and Endothelial Activation in Migraine: Relationships Between HIF-1α, VEGF-A, and Arginine Metabolism. [PDF]

Biomedicines
Dumur S, Bagheri Asl MM, Aygun D, Konukoglu D, Uzun H.   +4 more
europepmc   +1 more source

Assessing the therapeutic potential of PDE‐5 inhibitors in adults: Insights from a multi‐omics study

Physiological Reports, Volume 14, Issue 18, September 2026.
Abstract Phosphodiesterase‐5 inhibitors have beneficial pleiotropic effects and hold promise as adjuvant treatments for cancer, dementia, and other disorders. Sixteen men and women aged 50–60 were administered daily sildenafil/tadalafil for 1 month. We characterized molecular signatures of sildenafil/tadalafil treatment via analyses and multi‐omics ...
Kristen A. McGovern, Traver J. Wright, Erik D. Marchant, Sean P. Kilroe, William J. Durham, E. Lichar Dillon, Marc M. Baum, Michael P. Kinsky, William K. Russell, Christopher S. Fry, Pratik Gongloor, Richard B. Pyles, Randall J. Urban, Blake B. Rasmussen, Melinda Sheffield‐Moore   +14 more
wiley   +1 more source

Effects of Nutritional Supplements on Vascular Function: A Narrative Review. [PDF]

J Clin Med
Katsanaki E, Georgiopoulos G, Thymis J, Pavlidis G, Katogiannis K, Nikolaou PE, Vlastos D, Parissis J, Lambadiari V, Ikonomidis I.   +9 more
europepmc   +1 more source

Safety of S‐acetyl glutathione as an novel food pursuant to Regulation (EU) 2015/2283

EFSA Journal, Volume 24, Issue 9, September 2026.
Abstract Following a request from the European Commission, the EFSA Panel on Nutrition, Novel Foods and Food Allergens (NDA) was asked to deliver an opinion on S‐acetyl glutathione (SAG) as a novel food (NF) pursuant to Regulation (EU) 2015/2283. The NF consists of > 97% (w/w) SAG, which is an acetylated tripeptide (i.e.
EFSA Panel on Nutrition, Novel Foods and Food Allergens (NDA), Dominique Turck, Torsten Bohn, Montaña Cámara, Jacqueline Castenmiller, Stefaan De Henauw, Ángeles Jos, Alexandre Maciuk, Inge Mangelsdorf, Breige McNulty, Androniki Naska, Kristina Pentieva, Alfonso Siani, Frank Thies, Francesco Cubadda, Thomas Frenzel, Ursula Gundert‐Remy, Francesca Marcon, Harry J. McArdle, Peter Moldeus, Monika Neuhäuser‐Berthold, Matthew Wright, Salvatore Multari, Maura Magani, Karen Ildico Hirsch‐Ernst   +25 more
wiley   +1 more source

Effect of L-Citrulline Supplementation on Endothelial Function and Body Composition in Post-COVID-19 Syndrome: A Randomized Clinical Trial. [PDF]

Nutrients
Fernanda SM, Arturo OT, Patricia SM, Dulce GI, Yazmín DG, Gamaliel AO, Susana GA, Samantha HL, Getsemani RS, Gabriela CG, Valeria MV.   +10 more
europepmc   +1 more source