Modification of substrate specificity of l-arginine oxidase for detection of l-citrulline [PDF]
Enzymatic detection of citrulline, a potential biomarker for various diseases, is beneficial. However, determining citrulline levels requires expensive instrumental analyses and complicated colorimetric assays. Although l-amino acid oxidase/dehydrogenase
Kei Yamamoto +4 more
doaj +5 more sources
Impact of dietary supplementation of L-citrulline to meat goats during gestation on reproductive performance [PDF]
Background Meat goat production is a worldwide industry with products such as meat, milk, soap, and fiber being produced. There are approximately 2.6Â million meat goats in the United States.
Makenzie G. Newton +9 more
doaj +3 more sources
L-Citrulline Improves Recovery of Enterocytes While Not Affecting Gut Microbiota in an In Vitro Model of Chemotherapy-Induced Gastrointestinal Mucositis [PDF]
Background/Objectives: Despite significant advancements in cancer treatment outcomes, side effects, such as gastrointestinal mucositis (GIM), continue to impair patients’ quality of life.
Wally van der Laan +4 more
doaj +2 more sources
Citrulline is one of the major precursors of ethyl carbamate in soy sauce, and the accumulation of citrulline is attributed to the metabolism of arginine by bacteria with the arginine deiminase (ADI) pathway.
Yuan-Ming Sun +2 more
exaly +3 more sources
The effects of L-Citrulline and Glutathione on Endurance performance in young adult trained males [PDF]
Background Citrulline may amplify the effects of L-arginine and nitric oxide concentration, which may augment vasodilation and blood flow, thereby enhancing aerobic exercise performance.
Hannah E. Cabre +3 more
doaj +2 more sources
Assessment of Registered Clinical Trial Designs: Comparison of L-Arginine and/or L-Citrulline Interventions for Hypertension [PDF]
Background: L-Arginine (Arg) is an essential amino acid and a precursor for the synthesis of vascular nitric oxide, while L-Citrulline is a non-essential amino acid substrate for increasing L-arginine.
Ashley Brett Hillsley +1 more
doaj +2 more sources
Dose-response effect of L-citrulline on skeletal muscle damage after acute eccentric exercise: an in vivo study in mice [PDF]
Background Eccentric exercise may trigger mechanical stress, resulting in muscle damage that may decrease athletic performance. L-citrulline potentially prevents skeletal muscle damage after acute eccentric exercise.
Dhoni Akbar Ghozali +4 more
doaj +3 more sources
The Effects of L-Citrulline on the Apparent Digestion and Metabolism of Nutrients, Blood Hormone Levels, Amino Acid Metabolism and the Diversity of Faecal Microbiota in Mares in the Later Stage of Pregnancy [PDF]
This study aimed to investigate the impact of dietary L-citrulline supplementation on the health of mares during late gestation. Thirty-two healthy mares in late pregnancy were randomly assigned to four groups: a control group (CON, 0 g/d) and three ...
Pengshun Liu +5 more
doaj +2 more sources
Palmitic acid-induced cell death: impact of endoplasmic reticulum and oxidative stress, mitigated by L-citrulline [PDF]
Objective Palmitic acid (PA), the most abundant saturated free fatty acids, induces apoptosis in bovine mammary epithelial cells (MECs). It is suggested that oxidative stress and endoplasmic reticulum (ER) stress are key mechanisms underlying PA-induced ...
Md. Rezwanul Habib +2 more
doaj +2 more sources
Vascular endothelial function deteriorates with age and disease, and the production of vasodilator factors like nitric oxide (NO) decreases. The free amino acid l-citrulline increases vasodilation and blood flow through increased NO production.
Sho Miyatake +3 more
doaj +1 more source

