Results 41 to 50 of about 13,339,760 (194)

Impact of supplementation with L-citrulline/arginine after liver transplantation in individuals with Urea Cycle Disorders. [PDF]

Mol Genet Metab, 2023
Objective: Liver transplantation (LTx) is an intervention when medical management is not sufficiently preventing individuals with urea cycle disorders (UCDs) from the occurrence of hyperammonemic events.
Posset R, Garbade SF, Gleich F, Nagamani SCS, Gropman AL, Epp F, Ramdhouni N, Druck AC, Hoffmann GF, Kölker S, Zielonka M, Urea Cycle Disorders Consortium (UCDC) and the European registry and network for Intoxication type Metabolic Diseases (E-IMD) consortia study group.   +11 more
europepmc   +3 more sources

Arginine and Citrulline for the Treatment of MELAS Syndrome

Journal of Inborn Errors of Metabolism and Screening, 2017
Mitochondrial encephalomyopathy, lactic acidosis, and stroke-like episodes (MELAS) syndrome is a maternally inherited mitochondrial disease with a broad spectrum of manifestations.
Ayman W. El-Hattab MD, FACMG, Mohammed Almannai MD, Fernando Scaglia MD, FACMG   +2 more
doaj   +1 more source

Folic acid, either solely or combined with L‐citrulline, improves NO signaling and ameliorates chronic hypoxia‐induced pulmonary hypertension in newborn pigs

Physiological Reports, 2021
Concomitant with developing pulmonary hypertension (PH), newborn piglets exposed to chronic hypoxia develop pulmonary vascular NO signaling impairments.
Matthew Douglass, Anna Dikalova, Mark R. Kaplowitz, Yongmei Zhang, Gary Cunningham, Marshall Summar, Candice D. Fike   +6 more
doaj   +1 more source

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

FEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise, Tiziano Mazza, Raffaella Scanga, Lara Console, Michele Galluccio, Cesare Indiveri   +5 more
wiley   +1 more source

Desenvolvimento de metodologia analítica por cromatografia líquida de alta eficiência e eletroforese capilar para análise de citrulina em matrizes biológicas: Ana Claudia Vieira; orientador, Flavio Henrique Reginatto. [PDF]

, 2014
A intensa busca por novos biomarcadores de doenças com intuito de melhorar o diagnóstico e acompanhar a evolução da doença tem feito os pesquisadores reavaliar compostos antes ignorados, como a citrulina.
Vieira, Ana Claudia
core  

Regulation of L-arginine synthesis from L-citrulline by L-glutamine in endothelial cells

, 1993
L-Arginine synthesis from L-citrulline was studied in cultured bovine venular, bovine aortic, human microvascular, and cloned human microvascular endothelial cells (EC).
C. J. Meininger, G. Wu
core   +1 more source

Arginine methylation as a regulatory ratchet in cancer: From substrate selection to malignant‐state stabilization

Molecular Oncology, EarlyView.
Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley   +1 more source

L-Citrulline ameliorates pathophysiology in a rat model of superimposed preeclampsia [PDF]

, 2022
Background and Purpose Preeclampsia, characterized by hypertension, proteinuria and restriction of fetal growth, is one of the leading causes of maternal and perinatal mortality.
Münzel, Thomas, Closs, Ellen I., Zhou, Yawen, Xia, Ning, Man, Andy W. C., Reifenberg, Gisela, Werner, Anke, Daiber, Andreas, Lam, Uyen D. P., Habermeier, Alice, Li, Huige   +10 more
core   +1 more source

Citrulline Improves Early Post-Ischemic Recovery or Rat Hearts In Vitro by Shifting Arginine Metabolism From Polyamine to Nitric Oxide Formation

Clinical Medicine Insights: Cardiology, 2018
Background: Reperfusion or reopening of occluded vessels is the gold standard to terminate ischemia. However, early functional recovery after reperfusion is often low requiring inotropic intervention.
Marc Heidorn, Tim Frodermann, Andreas Böning, Rolf Schreckenberg, Klaus-Dieter Schlüter   +4 more
doaj   +1 more source

L-Arginine and L-Citrulline for Prevention and Treatment of Pre-Eclampsia: A Systematic Review and Meta-Analysis. [PDF]

BJOG
BackgroundEvidence suggests L‐arginine may be effective at reducing pre‐eclampsia and related outcomes. However, whether L‐arginine can prevent or only treat pre‐eclampsia, and thus the target population and timing of initiation, remains unknown ...
Makama M, McDougall ARA, Cao J, Mills K, Nguyen PY, Hastie R, Ammerdorffer A, Gülmezoglu AM, Vogel JP.   +8 more
europepmc   +2 more sources