Results 191 to 200 of about 105,372 (282)

Drought and Fruit and Vegetables Production in California

open access: yesAgricultural Economics, Volume 57, Issue 3, May 2026.
ABSTRACT California's increasingly frequent and intense droughts are a pressing problem for the state's agriculture and the US food supply. California supplies more than half of all fruit and vegetables produced in the United States. This paper quantifies the severity of the problem by estimating the impacts of the drought on California's fresh fruit ...
Qingyin Cai   +2 more
wiley   +1 more source

Cytochrome P450 1A1 influences obesity‐induced pulmonary hypertension

open access: yesBritish Journal of Pharmacology, Volume 183, Issue 9, Page 1824-1844, May 2026.
Background and Purpose The contribution of obesity to pulmonary arterial hypertension (PAH) pathophysiology remains poorly understood. Adipose tissue synthesises estrogens via cytochrome P450 (CYP) 19A1 (aromatase), whereas circulating estrogens are metabolised in the lung by CYP1A1.
Joshua P. Dignam   +12 more
wiley   +1 more source

Analysis of the Surface Morphology of Dental Enamel Exposed to Ready-to-Drink Alcoholic Beverages. [PDF]

open access: yesInt J Dent
de Paiva MAA   +5 more
europepmc   +1 more source

Targeting the noradrenergic‐metabolic axis: A new strategy for sugar‐induced depression subtypes

open access: yesBritish Journal of Pharmacology, Volume 183, Issue 9, Page 2099-2122, May 2026.
Abstract Background and Purpose Lifestyle is closely related to major depressive disorder (MDD). Given the growing focus on the impact of diet on mental health, this study examined how dietary habits affect the pathophysiology of MDD. Experimental Approach Health check‐up data were analysed. Mice received sucrose under chronic unpredictable mild stress
Takatoshi Sakata   +13 more
wiley   +1 more source

Cascade Valorisation of Lemon-Processing Residues (Part I): Current Trends in Green Extraction Technologies and High-Value Bioactive Recovery. [PDF]

open access: yesFoods
Núñez-Pérez J   +6 more
europepmc   +1 more source

Enzymatic synthesis of bioactive quinolones and (thio)coumarins by fungal type III polyketide synthases

open access: yesThe FEBS Journal, Volume 293, Issue 9, Page 2673-2691, May 2026.
Quinolones are valuable scaffolds for drug discovery but are rare in nature. Here, we show that two fungal enzymes, AthePKS and FerePKS, can generate 2‐quinolones and two additional heteroaromatic scaffolds. Using AthePKS, we designed an artificial enzymatic cascade towards an antimicrobial quinolone from a simple precursor and implemented it in E ...
Nika Sokolova   +5 more
wiley   +1 more source

A Hanks‐type bacterial kinase, PknS, directly phosphorylates the alternative sigma factor EcfK to promote resistance to protist predation

open access: yesThe FEBS Journal, Volume 293, Issue 9, Page 2772-2793, May 2026.
The Xanthomonas citri Hanks‐type kinase PknS autophosphorylates and directly phosphorylates the alternative sigma factor EcfK at five residues. Besides the conserved residue T51 in the σ2 domain, phosphorylation of a residue in the linker between σ2 and σ4 is critical for EcfK activation by promoting its interaction with a positively charged pocket in ...
Lídia dos Passos Lima   +12 more
wiley   +1 more source

Waste citrus pseudolimon peels derived biochar assisted magnetic Zn + Al (LDH) nanocomposites for As (III) adsorption. [PDF]

open access: yesSci Rep
Sharma S   +10 more
europepmc   +1 more source

Novel Ligands for the Orphan Receptor GPR151 Modulate Morphine Action

open access: yesGenes to Cells, Volume 31, Issue 3, May 2026.
The new GPR151 ligands altered the analgesic effects of morphine. ABSTRACT GPR151 is an orphan G‐protein‐coupled receptor expressed on specific neurons. Its expression has been reported to be upregulated in the dorsal root ganglia in mouse nerve injury models, suggesting a role in pain transmission.
Hijiri Yoshida   +7 more
wiley   +1 more source

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