Results 71 to 80 of about 13,855 (204)

Human Pancreatic Cancer Organoids

Cell Proliferation, EarlyView.
This guideline establishes a comprehensive framework for the application of patient‐derived pancreatic cancer organoids. It outlines the stringent technical requirements and testing methods necessary to ensure high fidelity to the original tumor tissue, including morphological assessment, pathological biomarker expression (e.g., CK19, CK7), and genetic
Aina He, Xiaolin Lin, Xiaozhe Qian, Jiasheng Mu, Zhonghua Tao, Jin Gu, Yonggang Wang, Ting Han, Hongling Zhao, Yalong Wang, Jian Zhang, Zunqiang Zhou, Ligang Xing, Changchun Zhou, Dongyuan Zhu, Zengjun Liu, Gang Chen, Qinghe Zhou, Xiaoguang Wang, Shasha Zhao, Xiao Liu, Dongyan Cao, Bin Yu, Zebing Liu, Jiabei Wang, Gengming Niu, Guiying Wei, Maorong Chen, Weiping Wang, Xiaonan Kang, Junmei Zhou, Shuai Gong, Ying Xie, Jianming Zhang, Xianming Kong, Chunyan Dong, Yanmei Zou, Lina Tang, Aijin Ma, Hua Xiong, Xuemei Liu, Tongbiao Zhao, Jie Hao, Xiuying Xiao, Dongxi Xiang   +44 more
wiley   +1 more source

Clinical and Prognostic Significances of Cytokeratin 19 and KIT Expression in Surgically Resectable Pancreatic Neuroendocrine Tumors [PDF]

Journal of Pathology and Translational Medicine, 2015
Background: Pancreatic neuroendocrine tumors (PanNETs) are malignant endocrine neoplasms that present diverse clinical behaviors. Therefore, identification of biomarkers of PanNETs is important for stratification of the prognosis of PanNET patients ...
Eun-Mi Son, Joo Young Kim, Soyeon An, Ki-Byung Song, Song Cheol Kim, Eunsil Yu, Seung-Mo Hong   +6 more
doaj   +1 more source

Human Gallbladder Cancer Organoids

Cell Proliferation, EarlyView.
This guideline provides standardized requirements and quality control measures for human gallbladder cancer organoids, supporting their reliable application in research and precision medicine. It aims to promote methodological consistency, facilitate international collaboration, and accelerate translational research and clinical implementation.
Dongxi Xiang, Ting Gong, Yinjie Zhu, Bin Jia, Chen Zhang, Ning Tang, Weiping Wang, Yalong Wang, Laiping Zhong, Yanmei Zou, Jian Zhang, Zunqiang Zhou, Ligang Xing, Changchun Zhou, Dongyuan Zhu, Zengjun Liu, Gang Chen, Xiaoguang Wang, Zhan Wang, Aina He, Yonggang Wang, Zebing Liu, Jiabei Wang, Feng Xu, Ganglong Gao, Xiaonan Kang, Shuai Gong, Xianming Kong, Chunyan Dong, Aijin Ma, Gengming Niu, Guiying Wei, Hongling Zhao, Xiongxiong Lu, Jie Cao, Tongbiao Zhao, Zizhen Zhang, Yingbin Liu   +37 more
wiley   +1 more source

Soft‐Tissue Keratocyst: A Report of Two New Cases

Oral Surgery, EarlyView.
ABSTRACT Background Soft‐tissue keratocyst (STKC) is an extremely rare lesion whose histogenesis, nomenclature, and biological characterization remain uncertain, largely due to its close morphological similarity to intraosseous odontogenic keratocyst and its completely extragnathic location.
Lucas Fabian Polti, Nayara Conceição Marcos Santana, María Cassia Ferreira Aguiar, Júlio César Tanos Lacerda, Renata Resende, Wagner Henriques Castro, Silvia Ferreira de Sousa, Felipe Paiva Fonseca, Ricardo Alves Mesquita   +8 more
wiley   +1 more source

One-step nucleic acid amplification (OSNA) for intraoperative evaluation of sentinel lymph node status in breast cancer: a comparative study between CK19 protein expression and CK19 mRNA level in primary tumors and lymph node metastasis.

, 2013
The one-step nucleic acid amplification (OSNA) method is an increasingly used procedure for intraoperative analysis of sentinel lymph node (SLN) status in breast cancer patients.
PUGLISI, Fabio, Gerometta A, DI LORETO, Carla, Pegolo E1, Puppin C, DAMANTE, Giuseppe   +5 more
core   +1 more source

Cytological Identification of a Rhabdoid Variant of Pancreatic Neuroendocrine Neoplasm

Cytopathology, Volume 37, Issue 6, Page 641-647, November 2026.
Intracytoplasmic inclusions observed in rhabdoid‐type neuroendocrine tumours are evident on Giemsa staining and show strong cytokeratin (AE1/AE3) positivity on immunocytochemistry. This report describes the cytological features of a rare rhabdoid variant of pancreatic neuroendocrine neoplasm and highlights the diagnostic challenges associated with this
Miyu Okuda, Keishi Mizuguchi, Tatsuya Mori, Urara Okawa, Hiroko Ikeda   +4 more
wiley   +1 more source

CD56, HBME-1 and cytokeratin 19 expressions in papillary thyroid carcinoma and nodular thyroid lesions

Journal of Research in Medical Sciences, 2016
Background: Carcinomas of the thyroid follicular epithelium are the most common cancers of the endocrine system. In the diagnosis of thyroid nodules and tumors, the gold standard is histological evaluation.
Senay Erdogan-Durmus, Deniz Ozcan, Enver Yarikkaya, Ali Kurt, Aynur Arslan   +4 more
doaj   +1 more source

Mixed Neuroendocrine—Non‐Neuroendocrine Neoplasm (MiNEN) of the Gallbladder. A Case Report From a Low‐Resource Setting

Clinical Case Reports, Volume 14, Issue 10, October 2026.
ABSTRACT Mixed neuroendocrine–non‐neuroendocrine neoplasms (MiNENs) of the gallbladder are exceedingly rare entities. We report a case of a 35‐year‐old female with a palpable right hypochondrial mass. Imaging demonstrated a large polypoid gallbladder lesion with periportal lymphadenopathy. The patient underwent open cholecystectomy with lymphadenectomy.
Muhammad Farhan, Muhammad Imran, Beenish Sabir, Khalil Ahmad, Farheen Khan, Shahid Hussain, Zohaib Ahmed, Muhammad Asim, Iqra Mehmood, Rahmat Gul Omarzai   +9 more
wiley   +1 more source

Habitat radiomics and deep learning on gadoxetic acid-enhanced MRI for noninvasive assessment of CK19 expression and recurrence-free survival in hepatocellular carcinoma

Frontiers in Oncology
ObjectivesTo develop a non-invasive model for the preoperative prediction of Cytokeratin 19 (CK19) expression in hepatocellular carcinoma (HCC) based on clinical, radiologic, habitat radiomics, and deep learning features using gadoxetic acid-enhanced MRI,
Weihao Chen, Jingcheng Hu, Mingzhan Du, Tao Zhang, Chunyan Gu, Qian Wu, Yanfen Fan, Ximing Wang, Yixing Yu, Chunhong Hu   +9 more
doaj   +1 more source

CK19 Promotes Ovarian Cancer Development by Impacting on Wnt/β-Catenin Pathway.

OncoTargets and therapy, 2020
Epithelial ovarian cancer (EOC) is the most common type of ovarian cancer and is the most lethal gynecologic malignancy. Cytokeratin 19 (CK19) is a small type I cytokeratin. The aim of this study is to explore the functional role of CK19 and its underlying mechanism in EOC.The expression levels of CK19 in EOC tissues were identified by Western blotting
Lu,Qi, Qu,Hong, Lou,Tong, Liu,Chongdong, Zhang,Zhenyu   +4 more
openaire   +3 more sources