Results 81 to 90 of about 13,855 (204)

The correlation between poor prognosis and increased yes-associated protein 1 expression in keratin 19 expressing hepatocellular carcinomas and cholangiocarcinomas

BMC Cancer, 2017
Background The Hippo pathway plays a vital role in liver regeneration and development by determining cellular lineage and regulating cell proliferation and apoptosis.
KyuHo Lee, Kyoung-Bun Lee, Hae Yoen Jung, Nam-Joon Yi, Kwang-Woong Lee, Kyung-Suk Suh, Ja-June Jang   +6 more
doaj   +1 more source

Intra-operative rapid diagnostic method based on CK19 mRNA expression for the detection of lymph node metastases in breast cancer

, 2008
Staging by sentinel node (SN) biopsy is the standard procedure for clinically node-negative breast cancer patients. Intra-operative analysis of the SN allows immediate axillary lymph node (ALN) dissection in SN positive patients, but a quick, reliable ...
van Diest, Paul, Meijer, Chris J. L. M., Horstman, A., Snijders, Peter J. F., Brink, Antoinette A. T. P., Brink, A.A.T.P., Jiwa, Mehdi, Horstman, Anja, Meijer, C.J.L.M., Visser, M., Pol, Rene P., van Diest, P.J., Snijders, P.J.F., Visser, Mike, Jiwa, M., Pol, R.P.   +15 more
core   +1 more source

A Case of False-Negative Results in the One-Step Nucleic Acid Amplification Assay for Sentinel Lymph Node Metastasis in Breast Cancer with Low Cytokeratin 19 Expression

Case Reports in Oncology
Introduction: One-step nucleic acid amplification (OSNA) for the analysis of sentinel lymph nodes is now widely used as a reliable tool for the intraoperative diagnosis of breast cancer metastasis based on the quantification of CK19 mRNA ...
Ai Koyanagi, Akinari Kakumoto, Hajime Kuroda, Shogo Baba, Mami Koketsu, Oi Harada, Yasutaka Kato, Hiroshi Nishihara, Hiroyuki Kawami   +8 more
doaj   +1 more source

CCL16 inhibits tumor proliferation and metastasis in HCC by impacting CK19 phenotype

iLIVER
Cytokeratin 19-positive (CK19+) hepatocellular carcinoma (HCC) is an aggressive subtype with poor outcomes. The initiation and development of CK19+ HCC in the background of liver cirrhosis remains unclear. This study investigated the role of the cirrhosis-related gene C-C motif chemokine ligand 16 (CCL16) in the development of CK19+ HCC.Datasets from ...
Huigang Li, Jianyong Zhuo, Peiru Zhang, Jinyan Chen, Zuyuan Lin, Xudong Yang, Ruijie Zhao, Chenghao Cao, Wei Shen, Chiyu He, Hao Chen, Ting Lv, Xuyong Wei, Shusen Zheng, Xiao Xu, Di Lu   +15 more
openaire   +2 more sources

Utility of Immunohistochemistry Markers CK19, Gal-3, HBME-1 and Their Combinations for Differential Diagnosis of Thyroid Diseases

, 2023
Differential diagnosis is important for clinical management of cases with thyroid diseases. We aimed to find the most useful diagnostic panel including immunohistochemistry markers and BRAF 600E mutation for papillary thyroid carcinoma.
Tülin Öztürk, ÖZTÜRK, TÜLİN, ADAY, Aynur, Demir, Hale, Aynur Dağlar Aday, Hale Demir   +5 more
core   +1 more source

Breast Skin Lesions in a 79‐Year‐Old Woman

JEADV Clinical Practice, EarlyView.
Javier Lorenz‐Dolz, Fátima Mayo‐Martínez, Andrea Díez Santandreu, Onofre Sanmartín Jiménez, Ruggero Moro   +4 more
wiley   +1 more source

CK19 and CD99 immunoexpression profile in goblet cell (mucin-producing neuroendocrine tumors) and classical carcinoids of the vermiform appendix.

, 2007
The immunoexpression of CK19 recently has been identified as a marker of poor prognosis in pancreatic endocrine tumors and hepatocellular carcinoma. Conversely, the loss of expression of CD99 has been suggested to play a role in the tumorigenesis and ...
Alsaad, KO;Serra, S;Perren, A;Hsieh, E;Chetty, R
core   +2 more sources

Expression of Cytokeratin 19 (CK19) and Vascular Endothelial Growth Factor (VEGF) Genes in Peripheral Blood of Patients with Oral Squamous Cell Carcinoma (OSCC)

مجله دانشکده پزشکی اصفهان, 2019
Background: Oral squamous cell carcinoma (OSCC) is one of the 10 most common malignant tumors. This study aimed to evaluate the relevance of vascular endothelial growth factor (VEGF) and cytokeratin 19 (CK19) genes as biomarkers for diagnosis of OSCC ...
Parisa Nabavi, Abdolreza Mohamadnia, Maryam Naseroleslami, Naghmeh Bahrami   +3 more
doaj   +1 more source

The intermediate filament protein CK19 stabilizes CFTR at the plasma membrane

, 2008
The protein interactions that govern apical membrane CFTR stability and density are not entirely elucidated. We used CFTR immunoprecipitation from cell lysates of human airway epithelial cell lines (LBE-AA, expressing wt-CFTR, and LBE-KK, expressing ...
Sun, Fei, 22nd annual North American cystic Fibrosis Conference, Noël, Sabrina, Frizzell, Raymond, Peters, Kathi, Zhang , Ruilin   +5 more
core  

Clinical meaning of age-related expression of fecal cytokeratin 19 in colorectal malignancy

BMC Cancer, 2009
Background Colorectal cancer (CRC) is one of the leading causes of malignant death worldwide. Because young age of onset is often considered a poor prognostic factor for CRC, it is important to identify the poor outcomes of CRC in a younger population ...
Sun Hsiao-Lun, Lin Chih-Ming, Lee Chia-Long, Pan Shiann, Chen Shu-Hung, Chien Chih-Cheng, Yang Shung-Haur, Chang Chun-Chao, Huang Chi-Cheng, Wu Yih-Yiing, Yang Ruey-Neng, Huang Chi-Jung   +11 more
doaj   +1 more source