Results 31 to 40 of about 2,355 (182)

Antibodies to Highly Pathogenic A/H5Nx (Clade 2.3.4.4) Influenza Viruses in the Sera of Vietnamese Residents. [PDF]

Pathogens, 2021
To cause a pandemic, an influenza virus has to overcome two main barriers. First, the virus has to be antigenically new to humans. Second, the virus has to be directly transmitted from humans to humans. Thus, if the avian influenza virus is able to pass the second barrier, it could cause a pandemic, since there is no immunity to avian influenza in the ...
Ilyicheva T, Marchenko V, Pyankova O, Moiseeva A, Nhai TT, Lan Anh BT, Sau TK, Kuznetsov A, Ryzhikov A, Maksyutov R.   +9 more
europepmc   +5 more sources

Clade 2.3.4.4 H5 chimeric cold-adapted attenuated influenza vaccines induced cross-reactive protection in mice and ferrets. [PDF]

J Virol, 2023
ABSTRACT Clade 2.3.4.4 H5Nx subtype avian influenza viruses (AIVs) have circulated in poultry and wild birds worldwide. Recently, an increasing number of H5Nx human infection cases have been reported occurred. Live attenuated influenza vaccines demonstrate more advantages than other types of vaccines, such as ease of administration ...
Sun W, Xu J, Wang Z, Li D, Sun Y, Zhu M, Liu X, Li Y, Li F, Wang T, Feng N, Guo Z, Xia X, Gao Y.   +13 more
europepmc   +3 more sources

Pathology of A(H5N8) (Clade 2.3.4.4) Virus in Experimentally Infected Chickens and Mice. [PDF]

Interdiscip Perspect Infect Dis, 2019
The emergence of novel highly pathogenic avian influenza viruses (HPAIVs) in migratory birds raises serious concerns as these viruses have the potential to spread during fall migration. We report the identification of novel HPAIV A(H5N8) clade 2.3.4.4 virus that was isolated from sick domestic duck at commercial farm during the second wave of spread ...
Prokopyeva EA, Zinserling VA, Bae YC, Kwon Y, Kurskaya OG, Sobolev IA, Kozhin PM, Komissarov A, Fadeev A, Petrov V, Shestopalov AM, Sharshov KA.   +11 more
europepmc   +4 more sources

Intercontinental Movement of Highly Pathogenic Avian Influenza A(H5N1) Clade 2.3.4.4 Virus to the United States, 2021. [PDF]

Emerg Infect Dis, 2022
We detected Eurasian-origin highly pathogenic avian influenza A(H5N1) virus belonging to the Gs/GD lineage, clade 2.3.4.4b, in wild waterfowl in 2 Atlantic coastal states in the United States. Bird banding data showed widespread movement of waterfowl within the Atlantic Flyway and between neighboring flyways and northern breeding grounds.
Bevins SN, Shriner SA, Cumbee JC, Dilione KE, Douglass KE, Ellis JW, Killian ML, Torchetti MK, Lenoch JB.   +8 more
europepmc   +4 more sources

A highly pathogenic avian influenza virus H5N1 clade 2.3.4.4 detected in Samara Oblast, Russian Federation. [PDF]

Front Vet Sci
Avian influenza (AI) is a global problem impacting birds and mammals, causing economic losses in commercial poultry farms and backyard settings. In 2022, over 8,500 AI cases were reported worldwide, with the H5 subtype being responsible for many outbreaks in wild and domestic birds.
Glazunova A, Krasnova E, Bespalova T, Sevskikh T, Lunina D, Titov I, Sindryakova I, Blokhin A.   +7 more
europepmc   +4 more sources

Different Outcomes of Chicken Infection with UK-Origin H5N1-2020 and H5N8-2020 High-Pathogenicity Avian Influenza Viruses (Clade 2.3.4.4b)

Viruses, 2023
Clade 2.3.4.4 H5Nx highly pathogenic avian influenza viruses (HPAIVs) of the “goose/Guangdong” lineage have caused a series of European epizootics since 2014.
Amanda H. Seekings, Caroline J. Warren, Saumya S. Thomas, Fabian Z. X. Lean, David Selden, Benjamin C. Mollett, Pauline M. van Diemen, Ashley C. Banyard, Marek J. Slomka   +8 more
doaj   +1 more source

Marked neurotropism and potential adaptation of H5N1 clade 2.3.4.4.b virus in naturally infected domestic cats. [PDF]

Emerg Microbes Infect
In April 2024, ten cats died in a rural South Dakota (SD) residence, showing respiratory and neurological symptoms. Necropsy and laboratory testing of two cats confirmed H5N1 clade 2.3.4.4b infection. The viral genome sequences are closely related to recent SD cattle H5N1 sequences.
Chothe SK, Srinivas S, Misra S, Nallipogu NC, Gilbride E, LaBella L, Mukherjee S, Gauthier CH, Pecoraro HL, Webb BT, Pipas JM, Ramasamy S, Kuchipudi SV.   +12 more
europepmc   +4 more sources

Evolution, global spread, and pathogenicity of highly pathogenic avian influenza H5Nx clade 2.3.4.4. [PDF]

J Vet Sci, 2017
Novel subtypes of Asian-origin (Goose/Guangdong lineage) H5 highly pathogenic avian influenza (HPAI) viruses belonging to clade 2.3.4, such as H5N2, H5N5, H5N6, and H5N8, have been identified in China since 2008 and have since evolved into four genetically distinct clade 2.3.4.4 groups (A-D).
Lee DH, Bertran K, Kwon JH, Swayne DE.
europepmc   +3 more sources

Assessing potential pathogenicity of novel highly pathogenic avian influenza (H5N6) viruses isolated from Mongolian wild duck feces using a mouse model

Emerging Microbes and Infections, 2022
Several novel highly pathogenic avian influenza (HPAIVs) A(H5N6) viruses were reported in Mongolia in 2020, some of which included host-specific markers associated with mammalian infection. However, their pathogenicity has not yet been investigated. Here,
Bao Tuan Duong, Duc Duong Than, Ulaankhuu Ankhanbaatar, Delgerzul Gombo-Ochir, Gansukh Shura, Amartuvshin Tsolmon, Chris Ka Pun Mok, Ganzorig Basan, Seon Ju Yeo, Hyun Park   +9 more
doaj   +1 more source

Phylogenetic analysis reveals that the H5N1 avian influenza A outbreak in poultry in Ecuador in November 2022 is associated with the highly pathogenic clade 2.3.4.4b

International Journal of Infectious Diseases, 2023
The ongoing H5N1 outbreak in the Americas caused by clade 2.3.4.4 is causing unprecedented impact in poultry and wild birds. In November 2022, a highly pathogenic avian influenza A outbreak was declared in poultry in Ecuador, affecting more than 1.1 ...
Alfredo Bruno, Alonzo Alfaro-Núñez, Doménica de Mora, Rubén Armas, Maritza Olmedo, Jimmy Garcés, María Sol Vaca, Euclides De la Torre, David Jarrin, Lidia Burbano, Johanna Salas, Cristian Imbacuan, José Chanatasig, Margoth Barrionuevo, María Cristina Galante, Veronica Salas, Natalia Goñi, Juan Cristina, Christian Steffe Domingues, Lucas Oliveira Montesino, Fernanda Gomes Cardoso, Dilmara Reischak, Miguel Angel Garcia-Bereguiain   +22 more
doaj   +1 more source