Results 91 to 100 of about 57,560 (274)

Punctual mutations in 23S rRNA gene of clarithromycin-resistant Helicobacter pylori in Colombian populations

World Journal of Gastroenterology, 2018
AIM To characterize punctual mutations in 23S rRNA gene of clarithromycin-resistant Helicobacter pylori (H. pylori) and determine their association with therapeutic failure. METHODS PCR products of 23S rRNA gene V domain of 74 H.
A. J. Matta, D. C. Zambrano, A. Pazos
semanticscholar   +1 more source

Development of a physiologically‐based pharmacokinetic model for Ritonavir characterizing exposure and drug interaction potential at both acute and steady‐state conditions

CPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 523-539, March 2025.
Abstract Ritonavir (RTV) is a potent CYP3A inhibitor that is widely used as a pharmacokinetic (PK) enhancer to increase exposure to select protease inhibitors. However, as a strong and complex perpetrator of CYP3A interactions, RTV can also enhance the exposure of other co‐administered CYP3A substrates, potentially causing toxicity.
Lien Thi Ngo, Woojin Jung, Tham Thi Bui, Hwi‐yeol Yun, Jung‐woo Chae, Jeremiah D. Momper   +5 more
wiley   +1 more source

Efficacy and safety of nitazoxanide based quadruple regimen as first line therapy for treating Helicobacter pylori infected naïve patients

Journal of Infection in Developing Countries
Background: Eradication of H. pylori is a challenging issue in many parts of the world including Egypt. Aim: To evaluate the safety and efficacy of adding nitazoxanide as an adjuvant drug to the standard clarithromycin-based regimen, a single-center ...
Amro M Hassan, Muhammad Abdel-Gawad, Maie M Mahmoud, Emad Abdelrazzak, Safwat S Sawy, Mohamed A Sayed, Rasha Maree O Ali, Waleed S EL-Nasser, Mohamed Ahmad Younes Hussein, Mohamed Ramadan Izzaldin, Mohammed F Mohammed   +10 more
doaj   +1 more source

Antimicrobial resistance of Helicobacter pylori strains to five antibiotics, including levofloxacin, in Northwestern Turkey

Revista da Sociedade Brasileira de Medicina Tropical, 2015
INTRODUCTION: Antibiotic resistance is the main factor that affects the efficacy of current therapeutic regimens against Helicobacter pylori. This study aimed to determine the rates of resistance to efficacy clarithromycin, amoxicillin, tetracycline ...
Reyhan Caliskan, Hrisi Bahar Tokman, Yusuf Erzin, Suat Saribas, Pelin Yuksel, Bora Kazim Bolek, Ecehan Ozge Sevuk, Mehmet Demirci, Ozge Yılmazli, Ozer Akgul, Fatma Kalayci, Huseyin Cakan, Barik Salih, Kadir Bal, Bekir Kocazeybek   +14 more
doaj   +1 more source

Presentation1_Omadacycline Potentiates Clarithromycin Activity Against Mycobacterium abscessus.pptx

, 2021
Mycobacterium abscessus is a difficult respiratory pathogen to treat, when compared to other nontuberculus mycobacteria (NTM), due to its drug resistance.
Seunghyeon Jeon (11809076), June-Woo Park (1741036), Jichan Jang (125488), Nguyen Thanh Quang (11809070), Bo Eun Heo (11809073), Bui Thi Bich Hanh (9284097), Yujin Park (3061362)   +6 more
core   +1 more source

Resistance to clarithromycin and gastroenterologist's persistence roles in nomination for Helicobacter pylori as high priority pathogen by World Health Organization.

World Journal of Gastroenterology, 2017
Due to the increasing prevalence of clarithromycin resistance, future of management of Helicobacter pylori (H. pylori) infections need to be recognized.
A. Abadi
semanticscholar   +1 more source

Cystitis in guinea pigs (Cavia porcellus): Clinical findings and treatment outcomes

Veterinary Record, EarlyView.
Abstract Background This retrospective study examined the incidence, diagnostic methods, bacterial isolates, treatments and outcomes associated with cystitis in guinea pigs presented at a single clinic between 2009 and 2022. Methods The clinic's medical records database was reviewed using easyvet software to identify cases eligible for inclusion in the
Anika Mische, Kerstin Müller
wiley   +1 more source

High prevalence of H. pylori clarithromycin resistance mutations among Seattle patients measured by droplet digital PCR

Helicobacter, 2018
Treatment of Helicobacter pylori infection is often empiric; however, current guidelines for management of Helicobacter pylori infection advise against the use of standard triple therapy (clarithromycin, amoxicillin, and proton‐pump inhibitor) when ...
Sarah Talarico, Andrew S. Korson, Christina K. Leverich, Stephanie Park, F. Jalikis, M. Upton, E. Broussard, N. Salama   +7 more
semanticscholar   +1 more source

The study of mutation in 23S rRNA resistance gene of Helicobacter pylori to clarithromycin in patients with gastrointestinal disorders in Isfahan - Iran

Advanced Biomedical Research, 2014
Background: Helicobacter pylori antimicrobial resistance is an important factor responsible for treatment failure. The purpose of this study was evaluating the prevalence of point mutations in clarithromycin-resistant clinical isolates of H.
Farzad Khademi, Jamshid Faghri, Sharareh Moghim, Bahram Nasr Esfahani, Hossein Fazeli, Farkhondeh Poursina, Peyman Adibi, Masoumeh Madhi, Hajieh Ghasemian Safaei   +8 more
doaj   +1 more source

Concurrent clarithromycin and cyclosporin A treatment [PDF]

, 1998
Although macrolides have been associated with significant pharmacokinetic interactions, clarithromycin is considered to have a low interaction capacity. In this study, six transplant recipients treated with cyclosporin A also received
Azanza, J.R. (José Ramón), Lopez-de-Ocariz, A. (A.), Álvarez-Cienfuegos, J. (Javier), Sadaba, B. (Belén), Quiroga, J. (Jorge)   +4 more
core