Results 91 to 100 of about 41,122 (231)

Proton NMR Revisited: Negative Time Reconstruction Transforms Pure Shift and 2D J‐Spectroscopy

Chemistry–Methods, Volume 6, Issue 11, November 2026.
Negative time signal reconstruction of NMR data acquired in a modified spin echo distills complex spectra into enhanced resolution multiplets and a pure shift spectrum. Experiments typically take only 2 min, with sensitivity an order of magnitude better than current methods, making routine acquisition of pure shift NMR spectra practical. Proton nuclear
Gareth A. Morris, Ellie Davies, Ralph W. Adams, Mathias Nilsson, Soumya S. Roy   +4 more
wiley   +1 more source

Fluorescence in situ hybridization vs. epsilometer test for detection of clarithromycin‐susceptible and clarithromycin‐resistant Helicobacter pylori strains in gastric biopsies from children

, 2002
Aim: To compare the results of culture and epsilometer test with fluorescence in situ hybridization for the detection of Helicobacter pylori and the presence of clarithromycin-susceptible and clarithromycin-resistant strains in antral biopsies from ...
H. Rüssmann, Antoni, I., D. Störk, I. Antoni, Rüssmann, H., Koletzko, S., S. Koletzko, N. Lehn, A. Fischer, Fischer, A., Lehn, N., Störk, D., A. Feydt‐Schmidt, Feydt‐Schmidt, A.   +13 more
core   +1 more source

Efficacy and safety of nitazoxanide based quadruple regimen as first line therapy for treating Helicobacter pylori infected naïve patients

Journal of Infection in Developing Countries
Background: Eradication of H. pylori is a challenging issue in many parts of the world including Egypt. Aim: To evaluate the safety and efficacy of adding nitazoxanide as an adjuvant drug to the standard clarithromycin-based regimen, a single-center ...
Amro M Hassan, Muhammad Abdel-Gawad, Maie M Mahmoud, Emad Abdelrazzak, Safwat S Sawy, Mohamed A Sayed, Rasha Maree O Ali, Waleed S EL-Nasser, Mohamed Ahmad Younes Hussein, Mohamed Ramadan Izzaldin, Mohammed F Mohammed   +10 more
doaj   +1 more source

Two approaches to the use of benzo[c][1,2]oxaboroles as active fragments for synthetic transformation of clarithromycin

Journal of Enzyme Inhibition and Medicinal Chemistry, 2017
Clarithromycin (active against Gram positive infections) and 1-hydroxy-1,3-dihydrobenzo[c][1,2]oxaborole derivatives (effective for Gram negative microbes) are the ligands of bacterial RNA. The antimicrobial activities of these benzoxaboroles linked with
Gennady B. Lapa, Elena P. Mirchink, Elena B Isakova, Maria N Preobrazhenskaya   +3 more
doaj   +1 more source

Crystal structure of tyrosine‐tRNA synthetase from Helicobacter pylori G27

Acta Crystallographica Section F, Volume 82, Issue 11, Page 369-375, November 2026.
The production, crystallization and 2.2 Å resolution structure of H. pylori tyrosine‐tRNA synthetase are reported.Helicobacter pylori, a major cause of gastric ulcers and cancers, infects nearly half of the world's population. The crystal structure of a potential H.
David Igbalajobi, Jason E. Taylor, Raymond Gao, Jesuferanmi Ayanlade, Rachael Zigweid, Sandhya Subramanian, Hannah Udell, Thomas E. Edwards, Jan Abendroth, Donald Lorimer, Peter J. Myler, Bart Staker, Edmund Moses Ndip, Oluwatoyin A. Asojo   +13 more
wiley   +1 more source

Clarithromycin, ein neues Makrolid-Antibiotikum. Wirksamkeit bei puerperalen Infektionen und Übertritt in die Muttermilch [Clarithromycin, a new macrolide antibiotic. Effectiveness in puerperal infections and pharmacokinetics in breast milk] [PDF]

, 1993
The aims of this study were, to determine the pharmacokinetic parameters of clarithromycin and to study the passage of the drug into breast milk. Twelve patients (age 24 to 38; weight 44 to 83 kg), suffering from puerperal infections, were treated orally
Sedlmayr, T., Raasch, W., Kees, Frieder K., Petersen, F.   +3 more
core   +1 more source

Antibiotic Use for Cystitis and Risk of Treatment Failure in Pregnancy Following Gastric Bypass: A Cohort Study

Basic &Clinical Pharmacology &Toxicology, Volume 139, Issue 5, November 2026.
ABSTRACT Cystitis is common during pregnancy and requires effective antibiotic treatment to prevent complications. Gastric bypass surgery alters gastrointestinal anatomy and may impair oral drug absorption, raising concerns about antibiotic effectiveness.
Mette Østergaard Thunbo, Line Kolding, Samuel Azuz, Terese Matthesen Kamronn, Lene Høimark, Lars Henning Pedersen   +5 more
wiley   +1 more source

Phytochemical-induced reduction of pulmonary inflammation during Klebsiella pneumoniae lung infection in mice

Journal of Infection in Developing Countries, 2014
Introduction: Curcumin, a polyphenol derived from the herb Curcuma longa, has number of antioxidant, anti-inflammatory, antimicrobial, and anti-carcinogenic activities.
Shruti Bansal, Sanjay Chhibber
doaj   +1 more source

Synthesis, Characterization, and In Vitro Evaluation of New Amino‐Alcohol Quinolines as Promising Antimycobacterial Agents

ChemMedChem, Volume 21, Issue 20, 28 October 2026.
Nontuberculous mycobacteria (NTM) mainly Mycobacterium avium complex (MAC), are emerging pathogens responsible for pulmonary infections. The efficacy of the standard treatment is therefore compromised by the emergence of intrinsic and acquired resistance in MAC.
Elise Si Ahmed Charrier, François Peltier, Jean‐François Raimbert, Marie Perret, Claire Andréjak, Alexandra Dassonville‐Klimpt, Pascal Sonnet   +6 more
wiley   +1 more source

Characteristics of Helicobacter pylori antibiotic resistance: data from four different populations

Antimicrobial Resistance and Infection Control, 2019
Aims To describe the characteristics of Helicobacter pylori (H. pylori) antibiotic resistance in clinical isolates from four populations. Methods In total, 1463 H. pylori strains were examined for antibiotic resistance.
Dong-sheng Liu, You-hua Wang, Zhen-hua Zhu, Shuang-hong Zhang, Xuan Zhu, Jian-hua Wan, Nong-hua Lu, Yong Xie   +7 more
doaj   +1 more source