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DNA as a Pollutant: the Clinical Class 1 Integron
Current Pollution Reports, 2018When humans first tried to control bacterial growth with antimicrobials, DNA elements called integrons began to accumulate genes for resistance. The clinical class 1 integron accumulated diverse antibiotic resistance genes, spread into multiple bacterial species, colonized a wide range of animal and plant hosts, and spread to every continent.
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Diversity of class 1 integrons in an aquatic ecosystem
2020The emergence and rapid dissemination of antibiotic resistance is a most striking example of evolution in action, driven by lateral gene transfer. Lateral movement of genetic information is largely mediated by mobile genetic elements such as plasmids, transposons, integrons and genomic islands. These elements are able to move within or between genomes,
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Emergence of class 1 to 3 integrons among members of Enterobacteriaceae in Egypt
Microbial Pathogenesis, 2017In spite of the role of integrons as the main contributor to multidrug resistance worldwide, their prevalence in Egypt is still underestimated. In this work, we announce the emergence of class 2 and 3 integrons among Enterobacteriacae isolates from Mansoura University Hospitals.
Dina E. Rizk, Areej M. El-Mahdy
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The Contribution of Class 1 Integron to Antimicrobial Resistance in Stenotrophomonas maltophilia
Microbial Drug Resistance, 2014Two hundred clinical isolates of Stenotrophomonas maltophilia were examined for the presence of class 1 integron and for the susceptibility to 12 different antimicrobials and detergents. The prevalence of class 1 integron in S.
Yi-Wei, Huang +4 more
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Occurrence of a novel class 1 integron harboring qnrVC4 in Salmonella Rissen
Diagnostic Microbiology and Infectious Disease, 2017We described qnrVC4 in S. Rissen 166ANSS50, a swine isolate, which was detected in the study on quinolone resistance mechanisms of nontyphoidal Salmonella in Thailand. The isolate was found to harbor a ̴17-kb non-conjugative plasmid carrying qnrVC4 within 8.91kb of a novel In4-like class 1 integron (In805).
Sirirat, Luk-In +4 more
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Study on the excision and integration mediated by class 1 integron in Streptococcus pneumoniae
Microbial Pathogenesis, 2017As a novel antibiotic resistance mobile element, integron was recognized as a primary source of antibiotic genes among Gram-positive organisms for its excision and integration of exogenous genes. In this study, Streptococcus pneumoniae was subjected to investigate the excision and integration of class 1 integron with eight different plasmids.
Qun, Lin +5 more
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Class 1 Integrons and Virulence Genes in Salmonella enterica Isolates From Pork and Humans
International Journal of Antimicrobial Agents, 2011Rungtip Chuanchuen +2 more
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