Results 101 to 110 of about 168,672 (260)

Improving Frame-based Engagement Classification in E-Learning Using EfficientNet and Normalized Loss Weighting

open access: yesJurnal RESTI (Rekayasa Sistem dan Teknologi Informasi)
Engagement can be defined as how individuals are involved in and interact with a task that requires attention and emotional conditions. Engagement is an affective state positively correlated with learning processes.
Joseph Ananda Sugihdharma   +2 more
doaj   +1 more source

THE CRISIS OF HOMEWORK AND THE RESTRUCTURING OF IN-CLASS ENGAGEMENT

open access: yes
This study examines the emerging crisis surrounding traditional homework, particularly its diminishing pedagogical effectiveness in the context of the rapid integration of artificial intelligence (AI) into contemporary educational environments. It further explores how the “Flipped Classroom” model may serve as a viable alternative for restructuring ...
IBRAHIMOV, Elchin, Shixaliyeva, Fidan
openaire   +1 more source

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

open access: yesFEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani   +6 more
wiley   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

open access: yesFEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young   +7 more
wiley   +1 more source

Acute caffeine treatment protects the developing retina from ischemia‐induced cell death

open access: yesFEBS Open Bio, EarlyView.
Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento   +6 more
wiley   +1 more source

Examining latent trajectories of participant engagement in a 12-month eHealth weight management intervention

open access: yesDigital Health
Objective Engagement with self-monitoring is crucial for success in digital behavior change interventions for weight loss, but little is known about trajectories of engagement, nor valid predictors of these trajectories.
Julianne M Power   +5 more
doaj   +1 more source

Student Engagement in a Large Flipped Class

open access: yes
This paper reports on two criminal law classes in which I instituted a flipped-class methodology. The classes were mandatory and contained large numbers of students (over 120 in each). The asynchronous out-of-class materials were well received but students were reluctant to engage in discussions and other interactive activities in the synchronous ...
openaire   +2 more sources

Small RNA pathways in mammalian oocytes

open access: yesFEBS Open Bio, EarlyView.
Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley   +1 more source

How phagocytic cells kill bacteria: Lessons from a professional killer

open access: yesFEBS Open Bio, EarlyView.
How phagocytic cells ingest and kill bacteria has been studied for more than a century, but many questions remain unanswered. The study of the amoeba Dictyostelium discoideum brings new answers, and new questions. Professional phagocytic cells such as neutrophils and macrophages, as well as free‐living soil amoebae like Dictyostelium discoideum, employ
Otmane Lamrabet, Pierre Cosson
wiley   +1 more source

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