Results 91 to 100 of about 1,461,687 (263)
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
This study aims to determine the effect of the Project Based Learning (PjBL) model with the STEAM (Science, Technology, Engineering, Arts, and Mathematics) approach on students’ learning interest and mathematics learning outcomes in Grade VII at SMP ...
Kevin Marito Sihombing +1 more
doaj +1 more source
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
EFEKTIVITAS PENGGUNAAN MEDIA FILM UNTUK MENINGKATKAN MINAT DAN HASIL BELAJAR EKONOMI SISWA KELAS X
Penelitian ini dilakukan dengan tujuan untuk mengatahui: 1) efektivitas media film dalam meningkatkan minat dan hasil belajar Ekonomi siswa, 2) perbedaan peningkatan minat belajar siswa yang menggunakan media film dengan siswa yang tidak menggunakan ...
Hayyun Lathifaty Yasri, Endang Mulyani
doaj
This research aims to determine the effect of using interactive PowerPoint learning media on students' interest in learning mathematics. The population of this study was class VII students of Madrasah Tsanawiyah. Of the 3 existing classes, 2 classes were
Toto Hermawan +4 more
doaj +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
On an Interesting Class of Variable Exponents
10 ...
Karlovich, Alexei Yu. +1 more
openaire +2 more sources
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
This research is a type of development research or Research and Development (R&D) with the ADDIE development model. Data collection techniques in this study were through questionnaires, interviews, and documentation. Data obtained from the questionnaire
Faizah Nurrahma +2 more
doaj +1 more source
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source

