Results 21 to 30 of about 5,426,120 (248)

Personalized Selumetinib Dosing in Pediatric Neurofibromatosis Type 1: Insights From a Pilot Therapeutic Drug Monitoring Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate selumetinib exposure using therapeutic drug monitoring (TDM) in pediatric patients with neurofibromatosis type 1 (NF1) and plexiform neurofibromas (PN), assess interpatient pharmacokinetic variability, and explore the relationship between drug exposure, clinical response, and adverse effects.
Janka Kovács, Zoltán Köllő, Balázs Gellért Karvaly, Mahmoud Obeidat, Rita Nagy, Péter Hegyi, Brigitta Teutsch, Eszter Tuboly, Miklós Garami   +8 more
wiley   +1 more source

Working-Class Power, Capitalist-Class Interests, and Class Compromise [PDF]

American Journal of Sociology, 2000
This article proposes a general theoretical framework for understanding the concept of "class compromise" in terms of a "reverse-J" model of the relationship between the associational power of workers and the interests of capitalists: increases in working-class power adversely affect capitalist-class interests until such power crosses some intermediate
openaire   +1 more source

INTEREST OF ENTRANCE TO HIGHER EDUCATION FOR CLASS XII STUDENTS OF AUTOMOTIVE AND ELECTRONIC SKILLS PROGRAM AT STATE VOCATIONAL HIGH SCHOOL 1 SEYEGAN [PDF]

, 2011
This study aims to find out the interest of entrance to higher education for Class XII Students of Automotive and Electronic Skills Program at State Vocational High School 1 Seyegan and find out the factors that interest influencing of entrance to higher
Suhirno, Suhirno
core  

Adherence to Protocol Recommendations for Children With Wilms Tumour in Two Consecutive Studies in the United Kingdom and Ireland—Does Variation Matter?

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background and Aims Wilms tumour (WT) has excellent event‐free and overall survival (OS). However, small differences exist between countries participating in the same international study. This led us to examine variation in adherence to protocol recommendations as a potential contributing factor.
Suzanne Tugnait, R. Al‐Saadi, A. Lopez‐Cortes, K. Dzhuma, M. Oostveen, J. Brok, S. Irtan, M. Weeks, J. Bate, S. Baker, R. Williams, M. Powis, D. Saunders, O. Olsen, T. Watson, S. Shelmerdine, S. Vaidya, L. Howell, C. Duncan, G. M. Vujanic, C. Stiller, G. P. Balchin, T. Chowdhury, K. Pritchard‐Jones   +23 more
wiley   +1 more source

EFFECT OF INDUSTRY EXPERIENCE WORKING PRACTICES AND RESULTS OF ENTREPRENEURIAL LEARNING INTEREST IN ENTREPRENEURSHIP ONLINE CLASS XII NETWORK COMPUTER ENGINEERING ENTIRE SMK NEGERI REGENCY KULON PROGO ACADEMIC YEAR 2012/2013 [PDF]

, 2013
This study aimed to determine the effect of industry experience working practices and learning outcomes of entrepreneurship either individually or jointly to the online student interest in entrepreneurship class XII network computer engineering entire ...
Cahyo, Ariwibowo
core  

Box Drawings for Learning with Imbalanced Data [PDF]

, 2014
The vast majority of real world classification problems are imbalanced, meaning there are far fewer data from the class of interest (the positive class) than from other classes.
Abe N., Chawla N. V., Qi Y., Sniadecki J., Wu G.   +4 more
core   +3 more sources

Sirolimus for Extracranial Arteriovenous Malformations: A Scoping Review of the Evidence in Syndromic and Non‐Syndromic Cases

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Arteriovenous malformations (AVMs) are rare, high‐flow, vascular anomalies that can occur either sporadically or as part of a genetic syndrome. AVMs can progress with serious morbidity and even mortality if left unchecked. Sirolimus is an mTOR inhibitor that is effective in low‐flow vascular malformations; however, its role in AVMs is unclear.
Will Swansson, Ingrid Winship, Gary Hammerschlag, Laura Scardamaglia   +3 more
wiley   +1 more source

Admissibility of the usual confidence interval in linear regression

, 2010
Consider a linear regression model with independent and identically normally distributed random errors. Suppose that the parameter of interest is a specified linear combination of the regression parameters. We prove that the usual confidence interval for
Giri, Khageswor, Kabaila, Paul, Leeb, Hannes   +2 more
core   +1 more source

Evaluating the Utility of Paired Tumor and Germline Targeted DNA Sequencing for Pediatric Oncology Patients: A Single Institution Report

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate the diagnostic yield and utility of universal paired tumor–normal multigene panel sequencing in newly diagnosed pediatric solid and central nervous system (CNS) tumor patients and to compare the detection of germline pathogenic/likely pathogenic variants (PV/LPVs) against established clinical referral criteria for cancer ...
Natalie Waligorski, Rebecca Ronsley, Shannon M. Stasi, Jeffrey Stevens, Erin R. Rudzinski, Christina M. Lockwood, Sarah E. S. Leary, Bonnie L. Cole, Michelle A. Ting, Vera Paulson   +9 more
wiley   +1 more source

Preventing the Subversion of \u3ci\u3eDevlin v. Scardelletti\u3c/i\u3e [PDF]

, 2005
In 2002, the U.S. Supreme Court ruled in Devlin v. Scardelletti that objecting class members could appeal a federal district court’s approval of a class settlement without first intervening in the litigation. Public interest lawyer Brian Wolfman says the
Wolfman, Brian
core   +1 more source