Results 31 to 40 of about 277,934 (283)

The role of salivary and intestinal complement system inhibitors in the midgut protection of triatomines and mosquitoes. [PDF]

PLoS ONE, 2009
Saliva of haematophagous arthropods contain biomolecules involved directly or indirectly with the haematophagy process, and among them are encountered some complement system inhibitors.
Veruska Cavalcanti Barros, Jéssica Góes Assumpção, André Miranda Cadete, Vânia Cristina Santos, Reginaldo Roris Cavalcante, Ricardo Nascimento Araújo, Marcos Horácio Pereira, Nelder Figueiredo Gontijo   +7 more
doaj   +1 more source

Complement-coagulation cross-talk: a potential mediator of the physiological activation of complement by low pH

Frontiers in Immunology, 2015
The complement system is a major constituent of the innate immune system. It not only bridges innate and adaptive arms of the immune system but also links the immune system with the coagulation system.
Hany Ibrahim Kenawy, Ismet eBoral, Alan eBevington   +2 more
doaj   +1 more source

Different Complement Activation Pathways Underly Cognitive Impairment and Type 2 Diabetes Mellitus Combined With Cognitive Impairment

Frontiers in Aging Neuroscience, 2022
BackgroundThe immune response and the complement system are associated with cognitive impairment and diabetes mellitus, respectively. Activation of the complement system in these diseases occurs mainly through either the classical pathway or the ...
Zhenxing Li, Weiwei Zhang, Feng Gao, Feng Gao, Qiqiang Tang, Dongmei Kang, Yong Shen, Yong Shen   +7 more
doaj   +1 more source

The Functional Amyloid Curli Protects Escherichia coli against Complement-Mediated Bactericidal Activity

Biomolecules, 2018
Escherichia coli strains may be beneficial or pathogenic. Many E. coli strains that cause human disease, especially those responsible for bacteremia and sepsis, express virulence factors that impart resistance to the complement system.
Steven G. Biesecker, Lauren K. Nicastro, R. Paul Wilson, Çağla Tükel   +3 more
doaj   +1 more source

Peptide Inhibitor of Complement C1 (PIC1) Rapidly Inhibits Complement Activation after Intravascular Injection in Rats. [PDF]

PLoS ONE, 2015
The complement system has been increasingly recognized to play a pivotal role in a variety of inflammatory and autoimmune diseases. Consequently, therapeutic modulators of the classical, lectin and alternative pathways of the complement system are ...
Julia A Sharp, Pamela S Hair, Haree K Pallera, Parvathi S Kumar, Clifford T Mauriello, Julius O Nyalwidhe, Cody A Phelps, Dalnam Park, Nicole M Thielens, Stephen M Pascal, Waldon Chen, Diane M Duffy, Frank A Lattanzio, Kenji M Cunnion, Neel K Krishna   +14 more
doaj   +1 more source

Human pentraxin 3 binds to the complement regulator c4b-binding protein. [PDF]

PLoS ONE, 2011
The long pentraxin 3 (PTX3) is a soluble recognition molecule with multiple functions including innate immune defense against certain microbes and the clearance of apoptotic cells.
Anne Braunschweig, Mihály Józsi
doaj   +1 more source

Classical and alternate complement factor overexpression in non-obese weight matched women with polycystic ovary syndrome does not correlate with vitamin D

Frontiers in Endocrinology, 2022
IntroductionWomen with polycystic ovary syndrome (PCOS) exhibit complement factor expression changes that may be obesity-driven rather than an intrinsic facet of PCOS; furthermore, complement changes have been associated with vitamin D deficiency, a ...
Abu Saleh Md Moin, Thozhukat Sathyapalan, Alexandra E. Butler, Stephen L. Atkin   +3 more
doaj   +1 more source

Nonadiabatic transition paths from quantum jump trajectories [PDF]

, 2022
We present a means of studying rare reactive pathways in open quantum systems using Transition Path Theory and ensembles of quantum jump trajectories. This approach allows for elucidation of reactive paths for dissipative, nonadiabatic dynamics when the system is embedded in a Markovian environment.
arxiv   +1 more source

Pathways connecting two opposed bilayers with a fusion pore: A molecularly-informed phase field approach [PDF]

Soft Matter, 2020, 16, 366, 2019
A phase field model with two phase fields, representing the concentration and the head-tail separation of amphiphilic molecules, respectively, has been constructed using an extension of the Ohta-Kawasaki model (Macromolecules 19, 2621-2632 (1986)).
arxiv   +1 more source

Measuring Total Classical Pathway and Activities of Individual Components of the Mouse Complement Pathway

Bio-Protocol, 2021
The complement system is a central component of innate immunity, responsible for recognition and killing of bacteria by tagging invaders through opsonisation, thereby promoting phagocytosis, and by direct lysis.
Wioleta Zelek
doaj   +1 more source