Results 41 to 50 of about 277,934 (283)
DYSFUNCTION OF COMPLEMENT SYSTEM IN FAMILIAL MEDITERRANEAN FEVER
. During attacks of familial mediterranean fever (FMF), multiple systemic events are triggered, most of which promote autoinflammatory reactions. A molecular pattern of immune abnormalities in FMF is yet unclear.
G. M. Mkrtchyan+4 more
doaj +1 more source
The S1025 peptide is the major antidote to the YrzI toxin, which we renamed here as SpyT (Small Peptide YrzI Toxin) and SpyA (Small Peptide YrzI Antitoxin) (1). Degradation of the toxin–antitoxin spyTA mRNA, either by a translation‐dependent cleavage by the endoribonuclease Rae1 (2) or by direct attack by 3′‐exoribonucleases (3), also contributes to ...
Laetitia Gilet+4 more
wiley +1 more source
The power of microRNA regulation—insights into immunity and metabolism
MicroRNAs are emerging as crucial regulators at the intersection of metabolism and immunity. This review examines how miRNAs coordinate glucose and lipid metabolism while simultaneously modulating T‐cell development and immune responses. Moreover, it highlights how cutting‐edge artificial intelligence applications can identify miRNA biomarkers ...
Stefania Oliveto+2 more
wiley +1 more source
A Comparison of the Pathway Tools Software with the Reactome Software [PDF]
This document compares SRI's Pathway Tools (PTools) software with the Reactome software. Both software systems serve the pathway bioinformatics area, including representation and analysis of metabolic pathways and signaling pathways. The comparison covers pathway bioinformatics capabilities, but does not cover other major facets of Pathway Tools that ...
arxiv
In lymphoid organs, antigen recognition and B cell receptor signaling rely on integrins and the cytoskeleton. Integrins act as mechanoreceptors, couple B cell receptor activation to cytoskeletal remodeling, and support immune synapse formation as well as antigen extraction.
Abhishek Pethe, Tanja Nicole Hartmann
wiley +1 more source
Alterations in the complement cascade in post-traumatic stress disorder
Background In the present study we assessed the functional state of the major mediator of the immune response, the complement system, in post-traumatic stress disorder (PTSD).
Hovhannisyan Lilit P+3 more
doaj +1 more source
Pathway parameter and thermonuclear functions [PDF]
In the theory of thermonuclear reaction rates, analytical evaluation of thermonuclear functions for non-resonant reactions, including cases with cut-off and depletion of the tail of the Maxwell-Boltzmann distribution function were considered in a series of papers by Mathai and Haubold (1988).
arxiv +1 more source
Cell‐free and extracellular vesicle microRNAs with clinical utility for solid tumors
Cell‐free microRNAs (cfmiRs) are small‐RNA circulating molecules detectable in almost all body biofluids. Innovative technologies have improved the application of cfmiRs to oncology, with a focus on clinical needs for different solid tumors, but with emphasis on diagnosis, prognosis, cancer recurrence, as well as treatment monitoring.
Yoshinori Hayashi+6 more
wiley +1 more source
Direct versus Delayed pathways in Strong-Field Non-Sequential Double Ionization [PDF]
We report full-dimensionality quantum and classical calculations for double ionization of laser-driven helium at 390 nm. Good qualitative agreement is observed. We show that the classical double ionization trajectories can be divided into two distinct pathways: direct and delayed.
arxiv +1 more source
Nonclassical assembly pathways of anisotropic particles [PDF]
Advances in synthetic methods have spawned an array of nanoparticles and bio-inspired molecules of diverse shapes and interaction geometries. Recent experiments indicate that such anisotropic particles exhibit a variety of 'nonclassical' self-assembly pathways, forming ordered assemblies via intermediates that do not share the architecture of the bulk ...
arxiv +1 more source