Results 41 to 50 of about 387,249 (358)

Classical and alternative complement pathway activation by pneumococci [PDF]

Infection and Immunity, 1977
Sixty-two strains of Streptococcus pneumoniae were studied for their abilities to consume selected components of classical and alternative complement pathways in human sera. The classical pathway was blocked by chelating calcium with ethyleneglycol-bios (beta-aminoethyl ether)-N,N-tetraacetic acid and by removing C4. The alternative pathway was blocked
W P Reed, C G Stephens, Ralph C. Williams   +2 more
openaire   +2 more sources

Complement activation and protein adsorption by carbon nanotubes [PDF]

, 2006
As a first step to validate the use of carbon nanotubes as novel vaccine or drug delivery devices, their interaction with a part of the human immune system, complement, has been explored.
Flahaut, Emmanuel, Green, Malcolm L. H., Salvador-Morales, Carolina, Sim, Edith, Sim, Robert B., Sloan, Jeremy   +5 more
core   +2 more sources

Complementary Roles of the Classical and Lectin Complement Pathways in the Defense against Aspergillus fumigatus

Frontiers in Immunology, 2016
Aspergillus fumigatus infections are associated with a high mortality rate for immunocompromised patients. The complement system is considered to be important in protection against this fungus, yet the course of activation is unclear.
Anne Rosbjerg, Ninette Genster, Katrine Pilely, Mikkel-Ole Skjoedt, Gregory L Stahl, Peter Garred   +5 more
doaj   +1 more source

Early complementopathy predicts the outcomes of patients with trauma

Trauma Surgery & Acute Care Open, 2019
Background Complementopathy (rapid complement activation and consumption after trauma) has been reported in trauma patients, but the underlying mechanism of these phenomena and their clinical significance remain unclear. This study aimed to determine the
Bin Liu, Yansong Li, Qingwei Zhao, Alexander Dixon, Leopoldo Cancio, Michael Dubick, Jurandir Dalle Lucca   +6 more
doaj   +1 more source

Borrelia miyamotoi FbpA and FbpB Are Immunomodulatory Outer Surface Lipoproteins With Distinct Structures and Functions

Frontiers in Immunology, 2022
Pathogens that traffic in the blood of their hosts must employ mechanisms to evade the host innate immune system, including the complement cascade. The Lyme disease spirochete, Borreliella burgdorferi, has evolved numerous outer membrane lipoproteins ...
Charles E. Booth, Alexandra D. Powell-Pierce, Jon T. Skare, Brandon L. Garcia   +3 more
doaj   +1 more source

Nucleation pathway of calcium sulfate hemihydrate (bassanite) from solution: implications for calcium sulfates on Mars [PDF]

J. Phys. Chem. C 2020, 2020
CaSO4 minerals (i.e. gypsum, anhydrite and bassanite) are widespread in natural and industrial environments. During the last several years, a number of studies have revealed that nucleation in the CaSO4-H2O system is non-classical, where the formation of crystalline phases involves several steps.
arxiv   +1 more source

Innate immune humoral factors, C1q and factor H, with differential pattern recognition properties, alter macrophage response to carbon nanotubes [PDF]

, 2015
Interaction between the complement system and carbon nanotubes (CNTs) can modify their intended biomedical applications. Pristine and derivatised CNTs can activate complement primarily via the classical pathway which enhances uptake of CNTs and ...
Ali-Boucetta, Andersen, Andersen, Andersen, Anthony G. Tsolaki, Balavoine, Basudev Paudyal, Bennie ten Haken, Bianco, Boncel, Cardoso, Carroll, Dumortier, Gaboriaud, Gadjeva, Ghai, Gudrun Stenbeck, Hamad, Haseeb A. Khan, Heister, Heister, Hussain, Jain, Ji, Kagan, Kang, Kirsten M. Pondman, Kishore, Kishore, Kishore, Kishore, Kojouharova, Kouser, Kouser, Lee, Li, Li, Lina Pednekar, Ling, Liu, Lubna Kouser, McDevitt, Moghimi, Mohamed H. Shamji, Muller, Pan, Pantarotto, Pondman, Pondman, Pondman, Pulskamp, Robert B. Sim, Roumenina, Russier, Rybak-Smith, Rybak-Smith, Rybak-Smith, Salvador-Morales, Salvador-Morales, Salvador-Morales, Shi, Sim, Singh, Tan, Tan, Uday Kishore, Verdejo, Wick, Xiao, Zhao, Zolnik   +70 more
core   +2 more sources

Complement protein levels in plasma astrocyte-derived exosomes are abnormal in conversion from mild cognitive impairment to Alzheimer's disease dementia. [PDF]

, 2019
IntroductionLevels of complement proteins (CPs) in plasma astrocyte-derived exosomes (ADEs) that are abnormal in Alzheimer's disease (AD) have not been assessed in mild cognitive impairment (MCI).MethodsParticipants (n = 20 per group) had either MCI ...
Elahi, Fanny M, Goetzl, Edward J, Rissman, Robert A, Schwartz, Janice B, Winston, Charisse N   +4 more
core   +2 more sources

Development of a C3c-based ELISA method for the determination of anti-complementary potency of Bupleurum polysaccharides

Acta Pharmaceutica Sinica B, 2015
Traditionally, determination of inhibitory potency of complement inhibitors is performed by the hemolytic assay. However, this assay is not applicable to the lectin pathway, thus impeding the understanding of complement inhibitors against the overall ...
Mulu Wu, Hong Li, Yunyi Zhang, Daofeng Chen   +3 more
doaj   +1 more source

Classical complement pathway activation in membranoproliferative glomerulonephritis

Kidney International, 1976
Levels of components of the classical and alternative complement pathways and the activity of the C3 nephritic factor (C3NeF) were measured in serum specimens from patients with type I (subendothelial deposits) and type II (intramembranous dense deposits) membranoproliferative glomerulonephritis (MPGN) and the results compared with the levels in normal
Clark D. West, Enrique H. Vallota, Yuet M. Ooi   +2 more
openaire   +3 more sources