Results 281 to 290 of about 660,625 (335)
Decoding monocyte heterogeneity in sepsis: a single-cell apoptotic signature for immune stratification and guiding precision therapy. [PDF]
Front PharmacolDuan W +5 more
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CADASIL or <i>NOTCH3</i> mutaion spectrum diseases? Interpretation of <i>NOTCH3</i> mutations and clinical heterogeneity in CADASIL. [PDF]
Front NeurolWang Y +5 more
europepmc +1 more source
The complement system in human pregnancy and preeclampsia. [PDF]
Front ImmunolKumar V, Stewart JH.
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Classical pathway complement activity in schizophrenia
Neuroscience Letters, 2005There is considerable evidence to suggest a role for complement in the pathogenesis of schizophrenia, but the data related to the classical pathway complement activity in patients with schizophrenia are conflicting. In the present study, the total hemolytic activity of the complement and the activities of individual complement components, C1, C2, C3 ...
Robert B. Sim +2 more
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Classical pathways of gene regulation by retinoids
2020Retinoic acid receptors were discovered during early studies of the actions and mechanisms of essential vitamins. Vitamin A is metabolized in the body to retinoic acid (RA) which is a key compound in the control of many developmental processes in chordates.
Ehmke Pohl, Charles W E Tomlinson
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The classic pathways of thyroid hormone metabolism
Molecular and Cellular Endocrinology, 2017Thyroid hormones (TH) are crucial for growth and development and play an important role in energy homeostasis. Although serum TH levels are relatively constant in the physiological state, TH bioavailability at the tissue and cellular level is dependent on local TH metabolism.
Anne H. van der Spek +2 more
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Effect of Concanavalin A on the Classical Complement Pathway
The Journal of Immunology, 1977Abstract Lysis of sheep erythrocytes (E) sensitized with anti-Forssman antiserum (EA) is inhibited by the action of concanavalin A (Con A) on whole guinea pig complement (GPC). The degree of inhibition observed for a given quantity of GPC was dependent on the Con A concentration.
J J, Langone, M D, Boyle, T, Borsos
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Current Protocols in Immunology, 1994
AbstractThis unit describes several assay methods that can be used to determine the functional status of the classical pathway of complement and to quantitate its component proteins. The classical pathway includes C1qrs, C2, C4, C3, C5, C6, C7, C8, and C9, listed in the order in which they interact.
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AbstractThis unit describes several assay methods that can be used to determine the functional status of the classical pathway of complement and to quantitate its component proteins. The classical pathway includes C1qrs, C2, C4, C3, C5, C6, C7, C8, and C9, listed in the order in which they interact.
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The Classical Pathway of Complement [PDF]
, 2016 Complement evolved in parallel with coagulation as part of the primordial explosion of life in the Cambrian era. Remnants of this connection still exist in vertebrate animals as well as invertebrates. A classic example is the horseshoe crab, Limulus polyphemus, still sought after by scientists today to test substances for traces of bacterial ...
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Control of the classical and the MBL pathway of complement activation
Molecular Immunology, 2000The activation of complement via the mannan-binding lectin (MBL) pathway is initiated by the MBL complex consisting of the carbohydrate binding molecule, MBL, two associated serine proteases, MASP-1 and MASP-2, and a third protein, MAp19. In the present report we used an assay of complement activation specifically reflecting the physiological activity ...
Petersen, Steen Vang +5 more
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